Micromonospora sp. HM134: FJK98_25925
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Entry
FJK98_25925 CDS
T06145
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
mich
Micromonospora sp. HM134
Pathway
mich00790
Folate biosynthesis
mich01100
Metabolic pathways
mich01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mich00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
FJK98_25925
Enzymes [BR:
mich01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
FJK98_25925
6.3.2.17 tetrahydrofolate synthase
FJK98_25925
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF3014
GHMP_kinases_C
Motif
Other DBs
NCBI-ProteinID:
QDY11881
UniProt:
A0A518WRK3
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Position
complement(6001994..6003325)
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AA seq
443 aa
AA seq
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MGRGEFAAVDAELAARGFTRMHFALDRIESLLDLLGSPQRAYPSIHLTGTNGKTSTARMI
DSLLRAFGLHTGRYTSPHLETVRERISLDGEPVDEQRFVATYREVKPLADLVDQRSAEPL
TYFDLTTALAFATFADAPVDVAVVEVGLGGAEDSTNVLQAGVAVLTPIGLDHTEWLGDTL
EDIALHKAGIIHSGATVIAAAQEEEAARPILERCAEVGATVAREGAEFGVLRRAVAVGGQ
VLTLQGLGGVYDEVFLPLHGAHQAQNAAVALAAVEAFLGAGAKRQLDVEAVREGFAATSS
PGRLEKVRNAPTVLLDGAHNPHGMAATVTALQEEFAFSKLVGVLAVLGDKDAAGLLELLE
PVLDSLVVTRNSSPRAMPADELAELAREVFGPDRVQVAAAMPDAIEAAVAEAEYDVPGEL
AGVGVLVTGSVVTVADARRLLKR
NT seq
1332 nt
NT seq
+upstream
nt +downstream
nt
gtgggtcgcggtgagttcgccgccgtcgacgcggagttggcggcgcgcgggttcacccgg
atgcacttcgcgctggaccgcatcgagtcgctgctcgacctgctcggcagcccgcagcgg
gcgtacccgtcgatccacctgaccgggacgaacggcaagacgtccacggcccggatgatc
gactcgctgctgcgggccttcggcctgcacaccggccgctacaccagcccgcacctggag
accgtccgggagcggatcagcctggacggggaaccggtcgacgagcaacgtttcgtcgcc
acctaccgcgaggtgaagccgctggccgacctggtcgaccagcggtcggccgagccgctg
acctacttcgacctgaccaccgcgttggcgttcgccacgttcgccgacgcgccggtcgac
gtggccgtggtggaggtggggctgggcggggccgaggactccaccaacgtgctccaggcc
ggggtggcggtgctcaccccgatcgggctggaccacaccgagtggctcggcgacaccctg
gaggacatcgccctgcacaaggccggcatcatccactccggcgcgacggtgatcgccgcc
gcccaggaggaggaggcggcccggccgatcctggaacggtgcgccgaggtcggcgccacg
gtcgcccgtgagggcgcggaattcggggtgctgcgccgggcggtcgccgtcggcggccag
gtgttgaccctccagggcctcggcggggtgtacgacgaggtgttcctcccgctgcacggt
gcacaccaggcacagaacgcggcggtggcgctggccgccgtcgaggcgttcctcggggcc
ggggccaagcggcagctcgacgtcgaggccgtccgggaggggttcgccgcgaccagctcc
ccgggccggctggagaaggtgcgcaacgccccgacggtgctgctggacggggcgcacaac
ccgcacgggatggccgccacggtcaccgcgctccaggaggagttcgcgttcagcaagctg
gtcggggtgctcgccgtgctcggcgacaaggacgcggccgggctgctggagctgctggag
ccggtgctcgactcgctcgtcgtcacccgcaacagctcgccccgggcgatgcccgccgac
gagttggccgagctggcccgggaggtcttcggcccggaccgggtgcaggtggccgccgcg
atgccggacgccatcgaggcggccgtcgccgaggccgagtacgacgtcccgggggagctg
gccggggtgggggtgctggtcaccggctcggtggtgacggtggccgacgcccgacggctg
ctgaagcgatga
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