Manis javanica (Malayan pangolin): 108388549 Help Entry 108388549         CDS       T06054                                  Symbol ADCY9 Name (RefSeq) adenylate cyclase type 9   KO K08049   adenylate cyclase 9 [EC:4.6.1.1] Organism mjv  Manis javanica (Malayan pangolin) Pathway mjv00230   Purine metabolism mjv01100   Metabolic pathways mjv01522   Endocrine resistance mjv04015   Rap1 signaling pathway mjv04020   Calcium signaling pathway mjv04022   cGMP-PKG signaling pathway mjv04024   cAMP signaling pathway mjv04062   Chemokine signaling pathway mjv04072   Phospholipase D signaling pathway mjv04114   Oocyte meiosis mjv04211   Longevity regulating pathway mjv04213   Longevity regulating pathway - multiple species mjv04261   Adrenergic signaling in cardiomyocytes mjv04270   Vascular smooth muscle contraction mjv04371   Apelin signaling pathway mjv04540   Gap junction mjv04611   Platelet activation mjv04713   Circadian entrainment mjv04714   Thermogenesis mjv04723   Retrograde endocannabinoid signaling mjv04724   Glutamatergic synapse mjv04725   Cholinergic synapse mjv04727   GABAergic synapse mjv04750   Inflammatory mediator regulation of TRP channels mjv04911   Insulin secretion mjv04912   GnRH signaling pathway mjv04913   Ovarian steroidogenesis mjv04914   Progesterone-mediated oocyte maturation mjv04915   Estrogen signaling pathway mjv04916   Melanogenesis mjv04918   Thyroid hormone synthesis mjv04921   Oxytocin signaling pathway mjv04923   Regulation of lipolysis in adipocytes mjv04925   Aldosterone synthesis and secretion mjv04926   Relaxin signaling pathway mjv04927   Cortisol synthesis and secretion mjv04928   Parathyroid hormone synthesis, secretion and action mjv04934   Cushing syndrome mjv04935   Growth hormone synthesis, secretion and action mjv04961   Endocrine and other factor-regulated calcium reabsorption mjv04962   Vasopressin-regulated water reabsorption mjv04970   Salivary secretion mjv04971   Gastric acid secretion mjv04972   Pancreatic secretion mjv04976   Bile secretion mjv05032   Morphine addiction mjv05163   Human cytomegalovirus infection mjv05166   Human T-cell leukemia virus 1 infection mjv05200   Pathways in cancer mjv05207   Chemical carcinogenesis - receptor activation mjv05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mjv00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     108388549 (ADCY9)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     108388549 (ADCY9)    04371 Apelin signaling pathway     108388549 (ADCY9)    04020 Calcium signaling pathway     108388549 (ADCY9)    04072 Phospholipase D signaling pathway     108388549 (ADCY9)    04024 cAMP signaling pathway     108388549 (ADCY9)    04022 cGMP-PKG signaling pathway     108388549 (ADCY9)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     108388549 (ADCY9)   09144 Cellular community - eukaryotes    04540 Gap junction     108388549 (ADCY9)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     108388549 (ADCY9)    04062 Chemokine signaling pathway     108388549 (ADCY9)   09152 Endocrine system    04911 Insulin secretion     108388549 (ADCY9)    04923 Regulation of lipolysis in adipocytes     108388549 (ADCY9)    04912 GnRH signaling pathway     108388549 (ADCY9)    04913 Ovarian steroidogenesis     108388549 (ADCY9)    04915 Estrogen signaling pathway     108388549 (ADCY9)    04914 Progesterone-mediated oocyte maturation     108388549 (ADCY9)    04921 Oxytocin signaling pathway     108388549 (ADCY9)    04926 Relaxin signaling pathway     108388549 (ADCY9)    04935 Growth hormone synthesis, secretion and action     108388549 (ADCY9)    04918 Thyroid hormone synthesis     108388549 (ADCY9)    04928 Parathyroid hormone synthesis, secretion and action     108388549 (ADCY9)    04916 Melanogenesis     108388549 (ADCY9)    04925 Aldosterone synthesis and secretion     108388549 (ADCY9)    04927 Cortisol synthesis and secretion     108388549 (ADCY9)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     108388549 (ADCY9)    04270 Vascular smooth muscle contraction     108388549 (ADCY9)   09154 Digestive system    04970 Salivary secretion     108388549 (ADCY9)    04971 Gastric acid secretion     108388549 (ADCY9)    04972 Pancreatic secretion     108388549 (ADCY9)    04976 Bile secretion     108388549 (ADCY9)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     108388549 (ADCY9)    04961 Endocrine and other factor-regulated calcium reabsorption     108388549 (ADCY9)   09156 Nervous system    04724 Glutamatergic synapse     108388549 (ADCY9)    04727 GABAergic synapse     108388549 (ADCY9)    04725 Cholinergic synapse     108388549 (ADCY9)    04723 Retrograde endocannabinoid signaling     108388549 (ADCY9)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     108388549 (ADCY9)   09149 Aging    04211 Longevity regulating pathway     108388549 (ADCY9)    04213 Longevity regulating pathway - multiple species     108388549 (ADCY9)   09159 Environmental adaptation    04713 Circadian entrainment     108388549 (ADCY9)    04714 Thermogenesis     108388549 (ADCY9)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     108388549 (ADCY9)    05207 Chemical carcinogenesis - receptor activation     108388549 (ADCY9)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     108388549 (ADCY9)    05163 Human cytomegalovirus infection     108388549 (ADCY9)   09165 Substance dependence    05032 Morphine addiction     108388549 (ADCY9)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     108388549 (ADCY9)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     108388549 (ADCY9)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     108388549 (ADCY9) Enzymes [BR:mjv01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      108388549 (ADCY9) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Motif Other DBs NCBI-GeneID:  108388549 NCBI-ProteinID:  XP_036870357 LinkDB All DBs Position Unknown AA seq 1352 aa AA seqDB search MASPPHQQLLRHHSTEASCDSSGDSNSVRVRIHPKPRSSSSHPKLCKYSISSCSSSGDSG ALPRRVGAGGRLRRQKRLPQLFERASSRWWNPRFDSVNLEEACMERCFPQTRRRFRYALF YIGVACLLWSVYFGVHMRAKLIVMAAPALCFLAVCAGFFLFTFTKLYARHYEWTSLVLTL LVFALTLAARFQVLTPLSGRGDSSNHTPSAKPTDACLSQVGSFSMCIEVLFLLYTVMHLP LYLSLFLGVAYSVLFETFGYHFQDKDRFPSPGTGAPHWELLSRALLHVCVHAIGIHLFIM SQVRSRSTFLKVGQSIMHGKDLEVEKALKERMIHSVMPRIIADDLMKQGDEESENSVKKH ATSSPKNRKKKSSMQKAPIAFRPFKMQQMEEVSILFADIVGFTRMSANKSAHALVGLLND LFGRFDRLCEETKCEKISTLGDCYYCVAGCPEPRADHAYCCIEMGLGMIRAIEQFCQEKK EMVNMRVGVHTGTVLCGILGMRRFKFDVWSNDVNLANLMEQLGVAGKVHISEATAKYLDD RYDMEDGKVTERLGQSIVADQLKGLKTYLIAGQRAKESHCSCSEALLSGFEVIDGSRVSS GPRGQGTASPGSVSDLAQTVKTFDNLKTCPSCGITFAPKSEAGAEGGAVQNGCQEEHRNS TKNSGEPNSKTQNGLLSPPQEEKLTNSQTSLCEILQEKGRWAGVSLDQSALLPLRFKNIR EKTDAHFVDVIKEDSLMKDYFFKPPINQFSLNFLAQELERTYRTSYQEEVIRNSPVQTFA SATFSSLLDVFLSTVVFLILSITCFLKYGAATAPPPPAALAVFAAALLLEVLSLVVSVRM VFFLEDVVACTKLLLEWIAGWLPRHFIGAILVSLPAVAVYSHVTSEFETNIHFTVFTGSA VLVAVVHYCNFCQLSSWMRSSLATIVGAGPLLLLYISLCPDSSVVISHTDAVQNFSSGRN PCNSSSPQDSRRPASLIGQEVILVFFLLLLLVWFLNREFEVSYRLHYHGDVEADLHRTKI QSMRDQADWLLRNIIPYHVAEQLKVSQTYSKNHDSGGVIFASIVNFSEFYEENYEGGKEC YRVLNELIGDFDELLGKPDYSSVEKIKTIGATYMAASGLNATQCQDGSHPQEHLQILFEF AKEMMRVVDDFNNNMLWFNFKLRVGFNHGPLTAGVIGTTKLLYDIWGDTVNIASRMDTTG VECRIQVSEESYRALSKMGYDFDYRGTVNVKGKGQMKTYLYPKCMDSGVVPQHQLSISPD IRVQVDGSIGRSPTDEITNLVPSVQNLDKTSLGSDNNSQAKDTHLSSRRPWKEPSKAEER CRFGKAIEKSDCEDMGMEEASELTKLNVSKSV NT seq 4059 nt NT seq  +upstreamnt  +downstreamnt atggcttccccgccccaccagcagctgctgcggcaccacagcaccgaggcgagctgtgac tccagcggggacagcaacagcgtgagggtcaggatccaccccaagccgcggtcctccagc agccaccccaaactctgcaagtacagcatctccagctgcagcagctccggggactcgggg gcgctgccccggagagtgggcgcgggaggccgcctgcgccggcagaagaggctgccccag ctgttcgagagagcctccagccgctggtggaaccccaggttcgactcggtgaacctggag gaggcttgcatggagcgctgcttcccgcagacgcggcgccgcttccggtatgcgctcttc tacatcggcgtcgcctgccttctgtggagcgtctatttcggggtccacatgagagccaaa ctgattgtcatggcagcccccgcactgtgcttcctcgcggtgtgtgcgggcttttttctg tttaccttcaccaagctctatgcccggcactacgagtggacctcgctggttctcaccctc ctggtgttcgccctgaccctggccgcccgcttccaggttttgacgccgctctcaggacgc ggcgacagctccaatcatactccctccgccaaacccacagacgcttgcttatcccaagtg gggagcttttccatgtgcatcgaagtgctctttttgctctacaccgtcatgcacttacct ttgtacttgagcttgtttttgggagtggcctactctgttctctttgagacctttggctat catttccaagacaaagaccgttttccttcgcctggcacaggggcccctcactgggagctg ctgagccgagccctgctccacgtctgcgttcatgccatcgggatccacctgttcatcatg tcccaggtgagatccaggagcaccttcctcaaggtgggacagtcaattatgcatgggaag gatctggaagtggagaaagccctgaaagagaggatgattcattctgtaatgcctagaata atagctgacgacttaatgaagcagggggatgaggagagtgagaattctgtcaaaaagcat gccacctccagccccaagaacaggaagaaaaaatcttccatgcagaaagcgcccatagca ttccgcccatttaagatgcagcagatggaagaagtcagtattttatttgcagatatcgtg ggcttcaccaggatgagtgccaacaaatctgctcatgccctggtgggtctcctcaacgat ctgtttggtcgctttgaccgattgtgcgaagagaccaagtgtgagaagatcagcaccctg ggagattgttactattgtgtggcagggtgtcctgagccccgggccgaccatgcctactgc tgcatcgaaatgggcttgggcatgataagagccattgagcagttctgccaagagaagaaa gagatggtgaacatgcgcgtgggggttcacacggggaccgtcttgtgtggtatcttgggc atgaggagatttaaatttgatgtatggtccaatgatgtgaacttggccaatctcatggag cagctgggagtggctggcaaggttcacatttcagaggccactgcaaaatacctagatgat cggtacgacatggaagatgggaaagttactgaacgcctcggtcagagcattgttgctgac cagttgaaaggtttgaagacatacctgatagcgggtcagagagcgaaggagtctcattgc agctgttcagaggccttgctttctggctttgaggtcattgacggctcacgggtgtcctca ggtcctaggggacaggggacagcatcaccagggagtgtcagtgacttggcgcagactgtc aaaacctttgataacttaaagacctgcccttcatgtggaatcacatttgctcccaaatcg gaagctggtgcagaaggaggagcagttcaaaatggctgtcaagaggagcatagaaacagc accaagaattctggagagcctaattccaaaacccaaaacggactcctgagtcctccccaa gaggagaagctcaccaacagtcagacgtccctgtgtgagatcctacaggaaaagggaagg tgggcaggtgtgagcttggaccagtcagctctccttccactgagattcaagaacatccgg gagaaaacagacgcccattttgtggatgttatcaaagaagacagcctgatgaaagattat ttttttaagccacccattaatcagttcagcctgaacttcctggctcaggagttagagcga acctataggaccagctatcaagaagaggtgataaggaattcccccgtgcagactttcgcc agtgccaccttcagctccctcctggatgtgtttctatcaacagtagtgtttctgattctc tccatcacctgcttcctgaagtatggggctgccaccgcacctcccccgcccgcagccctg gctgtctttgctgcagccctcctgctcgaagtgctgtcccttgtggtctctgtcaggatg gtgtttttcctggaggatgtggtggcttgcaccaagctcctgctggaatggatagctggc tggctcccgcgccacttcatcggcgccatcctcgtgtcactccccgctgtcgccgtctat tcacatgtcacctccgaatttgagacgaacatacatttcaccgtgttcacgggctcagct gtcctggtcgccgttgtgcactactgtaacttctgccagctcagctcctggatgaggtcc tccttagccaccattgttggggctgggcccctgctcctgttgtacatctctttgtgccca gatagttctgtagtaatttcacacactgatgcagtacagaatttcagttcagggaggaac ccgtgcaacagctcctcgccgcaggacagcaggaggccagccagcttgattggccaggag gtgattcttgtcttctttctcctgctcctgttggtctggttcctgaacagagaattcgaa gtcagctaccgcctccactaccatggggatgtggaggcggaccttcaccgcaccaagatc cagagcatgagggaccaagccgactggctgctgagaaacatcatcccctaccatgtggcc gagcagctaaaggtttcccaaacctactccaagaaccacgacagtgggggggtcatcttt gccagcattgtcaacttcagtgagttctacgaggagaactacgagggaggcaaggagtgc taccgggtcctgaacgagctgatcggggacttcgatgagctcctgggcaagccagattac agcagcgtggagaagatcaagaccatcggggccacgtacatggctgcgtcagggctaaat gccacccagtgccaggatggcagccacccgcaggagcacctgcagatcctgtttgaattt gccaaggagatgatgcgtgtggtggatgacttcaacaacaacatgctgtggttcaacttc aagctcagagttggcttcaaccatgggccactcaccgcgggggtcattgggaccaccaag ctgctgtatgacatctggggagacactgtcaacatcgccagcaggatggacactacaggg gtagagtgccgcatccaggtgagtgaagaaagctaccgcgctctgagcaagatgggctat gactttgactaccgtgggacagtaaatgtgaaggggaaaggccagatgaagacctacctt taccccaagtgcatggacagtggggttgtgccccaacaccagctgtccatctctccagac atccgagtccaggtggatggcagcatcggacggtctcccacggatgagatcaccaacctg gtgccttctgtacagaacttggataagacatctctgggttctgacaacaactcacaggcc aaggacactcacctgtcttccaggaggccctggaaagagcccagcaaagctgaagaaagg tgtcgatttggcaaagccatagaaaaaagtgactgtgaagacatggggatggaggaagcc agtgagctcaccaagctcaacgtgtcaaagagcgtgtaa

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