Manis javanica (Malayan pangolin): 108399878
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Entry
108399878 CDS
T06054
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X3
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv00061
Fatty acid biosynthesis
mjv00620
Pyruvate metabolism
mjv00640
Propanoate metabolism
mjv01100
Metabolic pathways
mjv04152
AMPK signaling pathway
mjv04910
Insulin signaling pathway
mjv04920
Adipocytokine signaling pathway
mjv04922
Glucagon signaling pathway
mjv04931
Insulin resistance
mjv04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
108399878 (ACACB)
00640 Propanoate metabolism
108399878 (ACACB)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
108399878 (ACACB)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
108399878 (ACACB)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
108399878 (ACACB)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
108399878 (ACACB)
04922 Glucagon signaling pathway
108399878 (ACACB)
04920 Adipocytokine signaling pathway
108399878 (ACACB)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
108399878 (ACACB)
04931 Insulin resistance
108399878 (ACACB)
Enzymes [BR:
mjv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
108399878 (ACACB)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
108399878 (ACACB)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
108399878 (ACACB)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
NTR2
ATP-grasp_3
Motif
Other DBs
NCBI-GeneID:
108399878
NCBI-ProteinID:
XP_017520382
LinkDB
All DBs
Position
Unknown
AA seq
2455 aa
AA seq
DB search
MILLLFLSSLVFSCLTFSWLKIWGKMTDPKHVAKSNLEASSVPSQEPFPAPDSLEEPLQK
NDSSSLPKTPKQAEPNSYNSSEDACRLRTSEPPLCQDLPPKTLSSDDASPAPQANGMGPE
GMKPPETNGLSSPARSQGQHARPLSKHDKKQEHIKRQLMTNFILGSFDDNSSDEDPGASW
FRESSRKGSRASLGALSLEAALTTSEPETPVPTLRPSMSGLHLQKRGREQKKLDLHRDFT
VASPAEFVTRFGGDRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPED
LKANAEFIKMADQYVPVPGGPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPEL
LCKHEIAFLGPPSKAMWALGDKIASTIVAQTLKIPTLPWSGSGLTVEWTEDSLQQGKRIN
VPEDVYNQGCVKDVEEGLEAAEKIGFPLMIKASEGGGGKGIRKADSAEDFPILFRQVQSE
IPGSTVFLMKLAQHARHLEVQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIATPAV
FEFMEQCAVHLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAA
QLQIAMGVPLHRLKDIRLLYGESPWGVTPISFETSSSPPLARGHVIAARITSENPDEGFK
PSSGTVQELNFRSSKNVWGYFSVAATGGLHEFADSQFGHCFSWGENREEAISNLVVALKE
LSIRGDFRTTVEYLINLLETESFQNNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNVA
DAMFRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGIKYILKVARQSLTMFVLIMNDC
HIEIDAHRLNDGGLLLSYNGNSYTTYMKEEVNSYRITIGNKTCVFEKENDPTVLRSPSAG
KLVQYKVEDGGHVEAGSSYAEIEVMKMVVALSVQESGRVRYIKRPGAMLEAGCLVARLEL
DDPSKVHPAKPFTGELPSQQTLPILGEKLHQVFHGVLENLTNIMSGYCLPEPIFSIKLKE
WVQKLMVTLRHPSLPLLELQDIMTSVSGRIPGPVEKAVRRVMAQYASNITSVLCQFPSQQ
IATILDCHAATLQRKADREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRRYLSVEHH
FQQAHYDKCVINLREQLKPDMSQVLDCIFSHSQVAKKNQLVIMLIDELCGPDPSLSDELT
SILNELTQLSKSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENL
KKLILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRQLPDGTCVVEF
QFMLPSSHPNRMAMPISITNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRRFEDFTRNFD
EVISCFANMPRDIPLFSKAHASLYSEDDSTSLREEPIHILNVAIQCADHLEDEELVPIFR
TFAQSKKNILVDYGLRRITFLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELS
RMRNFDLTAVPCANHKMHLYLGAARVQEGTEVTDHRFFIRAIIRHSDLITKEASFEYLQN
EGERLLLEAMDELEVAFNNTAVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLW
KLRVLQAEVKINIRQTTTGRAFPIRLFITNESGYYLDISLYKEVTDPRSGNILFHSFGNK
QGPQHGMLINTPYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPDKYPKDIL
TYTELVLDPQGQLVEMNRLPGGNEVGMVAFKMRLKTPEYPEGRDIIVISNDITFHIGSFG
LGEDFLYLRASEMARAEGIPKIYIAANSGARIGLAEEIKHMFQVAWVDPADPYKGFKYLY
LTPQDYTKISSLNSVHCKHIEEEGESRYVIMDIIGKDNGLGVENLKGSGMIAGESSLAYD
EIVTISLVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGV
QIMYYNGVSHITVPDDFEGVCAILEWLSYMPKDNHSPVPIITPTDPIDREIEFTPTRTPY
DPRWLLAGRPHPTLKGSWQSGFFDQGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRT
VEVVVPADPANLDSEAKILQQAGQVWLPDSAYKTAQVINDFNREKLPLMIFANWRGFSGG
TKDMYDQVLKFGSYIVDGLRQYKQPILIYIPLCAELRGGSWVVLDASINPLCIEIYADKD
SRQSILEPEGTVEIKFRKKDLIKTMRRIDPIYQKLVQQLGTPELSDKDRKDLEGQLKARE
DLLLPMYHQVAVHFADLHDMPDRLLEKSIISDVLEWKTSRTTLYWRLRRLLLEEQVRQEI
LRASSELSHAHIQSMLRRWFVESEGAVKAYLWDNNQMVVQWLEQHWQAGDSLHSTIRENI
GYLRRDSTRKTIQGLVQENPEVAVDCIVYMSQFLSPTERTQVIHLLSTMDSPAST
NT seq
7368 nt
NT seq
+upstream
nt +downstream
nt
atgatccttcttctttttctgtcttctctggttttctcctgcctgaccttttcctggcta
aaaatctgggggaaaatgacagaccccaagcacgttgccaagagtaatttggaagcaagc
tctgttccaagccaggagccctttccagccccagacagcttagaggagccactgcagaaa
aatgacagcagctctctgccaaagactcctaagcaggctgagccaaactcctacaacagc
tccgaagatgcctgtcggctcagaacctctgagccacccctttgccaggatcttccccca
aaaaccctttcctctgatgatgcctccccagcaccccaagccaatgggatgggacccgaa
ggcatgaagcccccagagaccaacggcctgtcctcaccagccaggtctcagggccagcac
gccagacccctttccaaacacgacaagaagcaggaacacatcaagaggcagctgatgact
aacttcatcctgggctccttcgacgacaactcctccgacgaggaccccggggccagctgg
ttccgagagtcttcgcggaagggcagccgagccagcctgggagccctgtctctggaggct
gctctgaccacaagcgagcctgagacccctgtccccactctaaggcccagcatgtcaggg
ctccacctgcagaagaggggccgcgagcagaagaagctggacttgcacagagactttact
gtagcttccccggctgagtttgtcacacgctttggtggggatcgggtcatcgaaaaggtg
ctcatcgccaacaatggcatcgctgctgtgaagtgcatgcgctccatccgcaggtgggcc
tatgagatgttccgcaatgagcgggccatccggtttgtagtcatggtgactccagaggat
ctgaaggctaatgcagagtttatcaagatggcagatcagtacgttcctgttccaggaggg
cccaataacaacaattacgccaacgtggagctgatcgtagacattgccaagagaatcccc
gtgcaggcggtgtgggccggttggggccatgcttctgaaaaccccaaacttccggagctc
ctgtgcaagcacgagattgctttcttaggccctcccagcaaggccatgtgggccctagga
gataagatcgcctccaccatcgtggcccagacgctgaagatcccaacgctgccctggagt
ggaagcggtctgacggtggagtggacggaagatagtctgcagcaggggaaaagaatcaat
gtcccagaagatgtttacaaccagggttgtgtgaaagatgtagaggaaggcttggaggca
gcagaaaaaattggttttccattgatgatcaaagcttctgaaggtggtggagggaaagga
atacggaaggcggatagtgccgaggacttcccaatccttttcagacaagttcagagtgag
atcccaggctccacggtctttctcatgaagctggcccagcatgcccgccacctggaggtc
cagatcctcgctgatcagtacgggaacgccgtgtctctgtttgggcgtgactgttccatc
cagcggcggcaccagaagatcattgaggaggcgccagccaccatcgccacaccagctgtg
ttcgagttcatggagcagtgtgcagtccacctggccaagactgtgggctacgtgagtgca
gggacggttgaatacctctatagccaggacggcagcttccacttcttggagctgaatccc
cgcctgcaggtggaacacccctgcacggaaatgatcgctgatgtcaacctgccagccgcc
cagctacagatcgccatgggcgtgccgctgcaccggctgaaggatatccggcttctgtat
ggagagtcaccatggggggtgacacctatttcttttgagacctcttccagccctcccctc
gcccgaggccacgtcattgcagccagaatcaccagtgaaaacccagatgaggggtttaag
ccgagctccggaacagtccaggagttgaatttccgcagcagcaagaatgtgtgggggtac
ttcagcgtggctgctactggtggcttacacgaatttgcggattcccagttcggacactgc
ttctcctggggagaaaaccgggaagaggccatttcgaacttggtggtggctttgaaggaa
ctgtccatccggggtgacttcaggaccaccgttgagtatctcattaacctgctggagacg
gagagcttccagaacaatgacatcgacactgggtggttggaccacctcatcgccgagaaa
gtgcaggctgagaagccagatatcatgctcggggtggtgtgcggagccttgaatgtggcc
gatgcaatgttcagaacctgcatgacggatttcctacattccctggaaaggggccaggtc
ctccccgcagattctctgctgaacatagtggacgtggaattaatttatggaggcattaag
tacattctcaaggtggcccggcagtctctgaccatgtttgtcctcatcatgaatgactgt
cacattgagattgatgcccaccggctgaatgacggtggactgctgctgtcctacaacggt
aacagctacaccacctacatgaaagaagaggtcaacagttaccgaattaccatcggcaac
aagacatgtgtgtttgagaaggagaatgatcccacagtcctgagatccccttcggctggg
aagctggtgcagtacaaggtggaggatgggggccatgtcgaggctgggagcagctacgct
gagattgaggtgatgaagatggtcgtggccctgagcgtgcaggaaagtggccgggtgaga
tacatcaagcgccccggggccatgctggaagcaggctgcctggtggccaggctggagctt
gatgatccttctaaagtgcacccggccaagccattcacaggagagctcccttcccagcaa
accctgcccatccttggggagaaactgcaccaggttttccacggggtcctggaaaacctg
accaacattatgagtggctactgtctgccagagcctatttttagcataaagctgaaggag
tgggtgcagaagctcatggtgaccctccggcacccgtcgctgccgctgctggagctgcag
gacatcatgaccagtgtgtcgggccgcatccctggccccgtggagaaggcggtgcgcagg
gtgatggctcagtatgccagtaacatcacctcggtgctgtgccagttccccagccagcag
atagccaccatcctggactgccacgcagccaccctgcagcggaaggctgaccgggaggtc
ttcttcatgaatacccagagcatcgtgcagttggtccagagataccgcagcgggacccgc
ggctacatgaagacagtggtactggatctcctgcgaagatacttaagcgtcgagcaccat
ttccaacaagcccactatgacaagtgtgtgataaacctcagggagcagctgaagccagac
atgtcccaggtgctggactgcatcttttcccattcgcaggtggccaagaagaaccagctg
gtgatcatgttgattgatgaactctgtggcccagacccttccttgtcggacgagctgacg
tccatcctcaacgagctcactcagctgagcaaaagcgagcactgcaaggtggccctcaga
gccagacaggtcctgattgcctcccacctcccctcctacgagctcaggcacaaccaggtg
gagtccattttcctctctgccatcgacatgtatggccaccagttctgcccagaaaacctc
aagaaattaatactctcagaaacgaccatatttgatgtcctgcccactttcttctaccat
gctaacaaagtcgtttgcatggcatccttagaggtttatgtgaggaggggctacatcgcc
tatgagttaaacagcctgcagcaccggcagctcccagacggtacctgcgtggtagaattc
cagttcatgttgccctcctcccacccgaaccggatggccatgcccatcagcatcaccaac
cctgacctgctgaggcacagcactgagctcttcatggacagcggcttctccccactgtgc
cagcggatgggtgccatggtcgccttccggagatttgaggatttcactaggaactttgac
gaagtcatctcctgcttcgccaacatgcccagggacatccccctcttcagcaaggcccac
gcgtccctgtactctgaggacgacagcacaagcctcagagaggagccaatccacatccta
aacgtggctatccagtgcgccgaccacctggaggatgaggagctggtgccgattttccgg
acgtttgcacagtccaagaaaaacatccttgtggattatgggctgcgaagaatcacgttc
ctgattgcccaagagaaagaatttcccaagtttttcacattcagagcaagagacgagttt
gccgaagatcgcatttaccgtcatttggagcccgccctggccttccagctggagctcagc
cggatgcgcaactttgatctcactgccgtgccctgtgccaaccacaagatgcacctttac
ctgggcgctgccagagtccaagaaggcacagaagtgacagatcacaggttcttcatccgt
gccatcatcaggcactcggacctgatcactaaggaagcctcctttgagtacctacagaac
gagggtgagcgtctgctcctggaggccatggacgagctggaggtggcgttcaacaacacg
gctgtgcgcacggactgcaaccacatcttcctcaacttcgtgcccaccgtcatcatggac
ccctccaagatcgaggagtctgtgcgctccatggttatgcgctacggcagccggctgtgg
aaactccgtgtgctacaggctgaggtcaagatcaacatccgacagaccaccaccggcagg
gcttttcccatccgcctgttcatcaccaacgagtcaggctactacctggacatcagcctc
tacaaggaagtcactgaccccagatctggaaacatcctgtttcactcctttggcaacaaa
cagggaccccagcacgggatgctgatcaacactccgtatgtcaccaaggatctgcttcag
gccaagcgcttccaggcccagtccctgggaaccacctacgtgtatgacttcccagagatg
ttcaggcaggctctctttaaactatggggctctccggacaagtaccccaaagacatcctg
acatacactgaactggtgctggaccctcagggccagctggtggagatgaatcgacttcct
ggaggaaacgaggtgggcatggtggccttcaaaatgagacttaagaccccagagtatcca
gaagggcgggacataattgtcatcagcaatgacatcaccttccacattggatccttcggc
ctgggagaagactttctgtacctgcgggcgtctgagatggcccgggcggagggtatcccc
aaaatctacattgcagccaacagtggggcccgtattggccttgcggaggaaatcaaacac
atgttccaggtggcttgggtggacccagcagacccctacaagggatttaaatatttgtac
ctgaccccccaagactacaccaaaatcagctccctgaactctgtccactgtaaacacatc
gaggaggagggagaatccaggtacgtcatcatggatatcattgggaaggacaatggcctg
ggcgtggagaacctgaaaggctcgggcatgatcgctggggagtcctcgctggcgtacgac
gagattgtcaccatcagcttggtgacctgccgagccctcgggatcggggcctacttggtg
aggctgggccagcgagtgatccaggtggaaaattcccacatcatcctgacgggagcaagt
gctctcaacaaggtcctgggcagagaggtgtacacgtccaacaaccagctcggcggcgtg
cagatcatgtattacaatggtgtctcccacatcaccgtgccagatgacttcgagggtgtc
tgtgccatcctggagtggctgtcctatatgccaaaggataaccacagtccagtccctatc
atcacgcccacggaccccatcgacagagaaattgaattcaccccaaccaggactccctac
gacccccgctggttgcttgcaggaaggcctcacccaactctgaagggatcctggcagagt
ggattctttgaccagggcagtttcaaggaaatcatggcaccctgggcccagacggtggtg
acgggccgtgcacggcttggggggatccctgtcggagtaattgccgtggagacacggact
gtggaggtggtggtgcctgcagaccctgccaacctggattctgaggccaagatactccag
caggcaggccaggtgtggttaccagactcagcctacaagacggcccaggtcatcaatgat
ttcaacagggagaagttgcccctaatgatctttgccaactggaggggcttctccggtggc
acgaaagacatgtatgaccaggtgctgaagtttgggtcctacatcgtggatggcctcagg
cagtacaaacagccgatcctgatctatatcccactctgtgcggagctccgggggggctcc
tgggtggtcttggatgcctccatcaaccccctgtgcatagaaatctatgcagacaaagac
agcaggcagagtattttggagccagagggaacagtagagattaagttccggaagaaagat
ttgataaagaccatgagaaggatcgacccaatttaccagaagctcgtgcagcagctagga
acgcctgagctgtccgacaaggaccgcaaggacctggagggccagctgaaggcccgggag
gacctgctgctgcccatgtaccaccaggtggcggtacactttgctgacctccacgacatg
cctgacaggttgctggagaagagcatcatctcagatgtcctggagtggaagacctcccgc
accactctgtactggcgtctgcgccgcctcctgctggaggagcaggtcaggcaggagatc
ctgcgggccagcagcgagctgagccacgcgcacatccagtccatgctgcgccgctggttt
gtggagtccgagggggccgtcaaggcctacctgtgggacaacaaccagatggtggtgcag
tggctggagcagcactggcaggcgggggacagcctgcactccaccatccgtgagaacatc
gggtacctcagaagggactccacccgcaagaccatccagggcctggttcaagaaaaccct
gaggtggctgtggactgcatagtatacatgagccagttcctcagcccgactgagcggacc
caagtcattcacctcctgtccaccatggacagcccagcctccacctga
DBGET
integrated database retrieval system
