Manis javanica (Malayan pangolin): 108401175
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Entry
108401175 CDS
T06054
Symbol
RPS6KB1
Name
(RefSeq) ribosomal protein S6 kinase beta-1 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
mjv
Manis javanica (Malayan pangolin)
Pathway
mjv01521
EGFR tyrosine kinase inhibitor resistance
mjv01522
Endocrine resistance
mjv04012
ErbB signaling pathway
mjv04066
HIF-1 signaling pathway
mjv04140
Autophagy - animal
mjv04150
mTOR signaling pathway
mjv04151
PI3K-Akt signaling pathway
mjv04152
AMPK signaling pathway
mjv04211
Longevity regulating pathway
mjv04213
Longevity regulating pathway - multiple species
mjv04350
TGF-beta signaling pathway
mjv04371
Apelin signaling pathway
mjv04666
Fc gamma R-mediated phagocytosis
mjv04714
Thermogenesis
mjv04910
Insulin signaling pathway
mjv04931
Insulin resistance
mjv05163
Human cytomegalovirus infection
mjv05165
Human papillomavirus infection
mjv05170
Human immunodeficiency virus 1 infection
mjv05200
Pathways in cancer
mjv05205
Proteoglycans in cancer
mjv05207
Chemical carcinogenesis - receptor activation
mjv05210
Colorectal cancer
mjv05212
Pancreatic cancer
mjv05221
Acute myeloid leukemia
mjv05224
Breast cancer
mjv05225
Hepatocellular carcinoma
mjv05226
Gastric cancer
mjv05231
Choline metabolism in cancer
mjv05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mjv00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
108401175 (RPS6KB1)
04350 TGF-beta signaling pathway
108401175 (RPS6KB1)
04371 Apelin signaling pathway
108401175 (RPS6KB1)
04066 HIF-1 signaling pathway
108401175 (RPS6KB1)
04151 PI3K-Akt signaling pathway
108401175 (RPS6KB1)
04152 AMPK signaling pathway
108401175 (RPS6KB1)
04150 mTOR signaling pathway
108401175 (RPS6KB1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
108401175 (RPS6KB1)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
108401175 (RPS6KB1)
09152 Endocrine system
04910 Insulin signaling pathway
108401175 (RPS6KB1)
09149 Aging
04211 Longevity regulating pathway
108401175 (RPS6KB1)
04213 Longevity regulating pathway - multiple species
108401175 (RPS6KB1)
09159 Environmental adaptation
04714 Thermogenesis
108401175 (RPS6KB1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
108401175 (RPS6KB1)
05205 Proteoglycans in cancer
108401175 (RPS6KB1)
05207 Chemical carcinogenesis - receptor activation
108401175 (RPS6KB1)
05231 Choline metabolism in cancer
108401175 (RPS6KB1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108401175 (RPS6KB1)
09162 Cancer: specific types
05210 Colorectal cancer
108401175 (RPS6KB1)
05212 Pancreatic cancer
108401175 (RPS6KB1)
05225 Hepatocellular carcinoma
108401175 (RPS6KB1)
05226 Gastric cancer
108401175 (RPS6KB1)
05221 Acute myeloid leukemia
108401175 (RPS6KB1)
05224 Breast cancer
108401175 (RPS6KB1)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
108401175 (RPS6KB1)
05163 Human cytomegalovirus infection
108401175 (RPS6KB1)
05165 Human papillomavirus infection
108401175 (RPS6KB1)
09167 Endocrine and metabolic disease
04931 Insulin resistance
108401175 (RPS6KB1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
108401175 (RPS6KB1)
01522 Endocrine resistance
108401175 (RPS6KB1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mjv01001
]
108401175 (RPS6KB1)
Enzymes [BR:
mjv01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
108401175 (RPS6KB1)
Protein kinases [BR:
mjv01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
108401175 (RPS6KB1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
DUF1015
Motif
Other DBs
NCBI-GeneID:
108401175
NCBI-ProteinID:
XP_036859935
LinkDB
All DBs
Position
Unknown
AA seq
525 aa
AA seq
DB search
MRRRRRRDGFYPAPDFRDREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG
PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF
AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL
FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC
KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK
TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL
LARKVEPPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE
SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTTNTQTPVEYPMETSG
IEQMDVTMSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL
NT seq
1578 nt
NT seq
+upstream
nt +downstream
nt
atgaggcgacgacggaggcgggacggcttttacccagcgccggacttccgagacagggaa
gctgaggacatggcaggagtgtttgacatagatctggaccagccagaggacgcgggctct
gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga
ccatatgaacttggcatggaacattgtgaaaaatttgaaatttcagaaactagtgtgaac
agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg
ggctatggaaaggtttttcaagtgcgaaaagtaacaggagcaaatactgggaaaatattt
gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca
aaagcagagcggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat
gcctttcagaccggtggaaaactctacctcatccttgagtatctcagtggaggagaatta
tttatgcagttagaaagagagggaatttttatggaagacacagcctgcttttacttggca
gaaatctccatggctttggggcatttacatcaaaaggggatcatctacagagacctgaag
ccggagaatatcatgcttaatcaccaaggtcatgtgaaactaacagactttggactatgc
aaagaatcgattcatgatggaacagtcacacacacattttgtggaacaatagaatacatg
gcccctgaaatcttgatgagaagtggccacaatcgtgctgtggattggtggagtttggga
gcattaatgtatgacatgctgactggagcacccccattcactggggagaatagaaagaaa
acaattgacaaaatcctcaaatgtaaactcaatttgcctccctacctcacacaagaagcc
agagatctgcttaaaaagctgctgaaaagaaatgctgcttctcgtcttggagctggtcct
ggggatgctggagaagttcaagctcatccatttttcaggcatattaactgggaagaactg
ctggctcggaaggtggagcctccctttaaacctctgttgcaatccgaagaggatgtgagt
cagtttgattcaaagtttacacgccagacacctgttgacagtccagatgactccactctc
agtgaaagtgccaaccaggtctttctgggttttacatatgtggctccatctgtacttgaa
agcgtgaaagaaaagttttcctttgaaccaaaaatccgatcacctcgaagatttattggc
agcccacgaacacctgtcagcccagtcaaattttctcctggggatttctggggaagaggt
gcttcagccagcacgacgaatactcagacgcctgtggaatacccaatggaaacaagtgga
atagagcagatggatgtgacaatgagtggggaagcttcagcaccacttccaatacgacag
ccgaactctgggccatacaaaaaacaagcttttcccatgatctccaaacgaccagagcac
ctgcgtatgaatctatga
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