Mycobacterium kansasii ATCC 12478: MKAN_05600
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Entry
MKAN_05600 CDS
T02887
Name
(GenBank) pyruvate dehydrogenase E1 subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
mkn
Mycobacterium kansasii ATCC 12478
Pathway
mkn00280
Valine, leucine and isoleucine degradation
mkn00640
Propanoate metabolism
mkn00785
Lipoic acid metabolism
mkn01100
Metabolic pathways
mkn01110
Biosynthesis of secondary metabolites
mkn01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
mkn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
MKAN_05600
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
MKAN_05600
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MKAN_05600
Enzymes [BR:
mkn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
MKAN_05600
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Motif
Pfam:
E1_dh
DXP_synthase_N
Transketolase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
AGZ49813
UniProt:
U5WKS6
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Position
complement(1260571..1261662)
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AA seq
363 aa
AA seq
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MARKCQTPMTVDLEPVQLIGPDGKPTAEERYSRDLSAETLCWLYEMMVVTRELDDEFVNL
QRQGELALFTPCRGQEAAQVGAAACLRAADWLFPQYRELGVYLVRGIPPGHVGAAWRGSW
HGGLEFTTKCCAPMSVPVGTQTLHAVGAAMAAQRLGEDSVTVPFLGDGATSEGDVHEALN
LAGVFRVPCLFYVQNNQWAISTPVRKQTAAVSIAHKAIGYGMPGIRVDGNDVLACYAVMA
EAATRARAGNGPSLIEAVTYRLGPHTTADDPTRYRDQQELDRWLALDPIPRFRRYLQDLG
LWSQSLEDRVAARSAGQRAELRDAVFDAPDFDVDELFTAVYAHITPELEAQRRQLRAELA
RTE
NT seq
1092 nt
NT seq
+upstream
nt +downstream
nt
atggctcggaagtgtcagacaccgatgacggtcgacctcgagccggtgcaactcataggt
ccagacgggaagccgaccgcggaagagcgttacagccgtgatctgtccgcggaaacactg
tgctggctctacgaaatgatggtggtcacacgggagctcgacgacgagttcgtgaacctg
cagcgccagggtgaattggcgctgttcacaccctgtcgcggccaggaggctgcccaggtg
ggggcggccgcatgcctgcgtgcggccgactggttgtttccgcaataccgcgaattgggc
gtatacctggtgcgcggcatcccgcccggacacgtgggcgccgcatggcgcggaagctgg
catggcgggctggaattcacgacgaaatgctgcgctccgatgtccgttccggttggcact
cagacattgcacgccgtcggcgccgcgatggccgcccaacgcctcggcgaggactcggtg
actgtccccttcctgggcgacggcgccaccagcgagggcgacgtccacgaggcgctgaat
ctcgcgggcgtattccgggtgccgtgcctgttctacgtgcagaacaaccagtgggcgata
tcgacgccagtccgaaagcagacggccgctgtttccatcgcgcacaaggcaatcggctat
gggatgcccggcatccgagtggacggcaacgatgtgctggcgtgctatgcggtgatggcc
gaggccgccactcgggcccgagccggtaacggtcccagcctgatcgaggcggttacctat
cgcctgggcccacacaccaccgccgacgacccgacccggtatcgcgaccagcaggagctg
gatcggtggctggctctggacccgattccgcgttttcggcgctacctgcaggacctgggg
ctgtggtcgcagagcctcgaggaccgggtcgccgcccgttcggcggggcaacgggccgaa
ctgcgcgatgccgtgtttgacgcgcccgatttcgacgtcgacgaactcttcaccgcggtc
tacgcccacatcacaccggagttggaagcgcagcgccggcagttgcgcgccgaattggcg
cggaccgagtag
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