Mycobacterium kiyosense: IWGMT90018_20350
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Entry
IWGMT90018_20350 CDS
T09155
Symbol
folC
Name
(GenBank) dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
mky
Mycobacterium kiyosense
Pathway
mky00790
Folate biosynthesis
mky01100
Metabolic pathways
mky01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
mky00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
IWGMT90018_20350 (folC)
Enzymes [BR:
mky01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
IWGMT90018_20350 (folC)
6.3.2.17 tetrahydrofolate synthase
IWGMT90018_20350 (folC)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
DUF2525
Motif
Other DBs
NCBI-ProteinID:
BDB41589
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Position
2048409..2049839
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AA seq
476 aa
AA seq
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MNPEPDWSEQVTDAAPTPDEIAALLQVEHLLDQRWPETKIEPSLTRISALLDLLGSPQLS
YPSIHIAGTNGKTSVARMVDALLTALQMRTGRTTSPHLQAAVERISIDGKPISPARYVAT
YREIEPFVQMIDEQAIAGGAPAMSKFEVLTAMAFAAFADAPVDVAVVEVGMGGRWDATNV
INAPVAVITPIGVDHVEYLGHDIGGIAGEKAGIITRAPDGSPDTVAVIGRQQPEAMEVLL
SQTVRADAAVAREDSEFAVLGRQVAIGGQVLELQGLGGVYTDIYLPLHGEHQAHNAAVAL
AAVEAFFGAGAQRQLDVDAVRAGFAAVASPGRMERMRSAPTVFIDAAHNPAGAAALARTL
TDEFDFATLVGVLSVMADKDVDGILAALEPVFDSIVVTHNGSPRALDVEGLALAAQQRFG
PDRVVTAENMRDAIDAATALVDAAQAEDLSSGAGIVITGSVVTAGAARTLFGRDPA
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgaatcccgagcctgactggtccgaacaggtcaccgacgccgcgcccacgccggacgag
atcgccgcactgctgcaggtcgagcatctgctggaccagcggtggccggaaaccaagatc
gagccgagcctgacccggatcagcgcgctgctggacctgctgggctcgccacagttgagt
tacccgtcgatccacatcgcgggcaccaacggcaagacttcggtggcccggatggtcgac
gcgttgctcaccgccctgcagatgcgtaccggacgtaccaccagcccgcacctgcaggcc
gcggtcgagcggatttcgatcgacggcaagccgatcagtccggcccggtatgtggcgacc
taccgggagatcgagccgttcgtgcagatgatcgacgaacaggcaattgctggcggggcc
ccggcgatgagcaagttcgaggtgctgaccgcgatggcgttcgcggcgttcgcggacgca
ccggtggacgtcgccgtcgtcgaggtggggatgggcggacgctgggacgccaccaacgtg
atcaatgcaccggtggccgtcatcaccccgatcggagtcgaccacgtggagtatctcggt
cacgacatcggtgggatcgcgggcgagaaggcgggcatcatcacccgggcgcccgacggc
tcgccggacaccgtcgcggtgatcggccggcagcagccggaggcgatggaggtgctgctg
agccagacggtgcgcgccgatgccgcggtggcccgcgaggattcggagttcgcggtgctg
gggcgccaggtcgcgatcgggggtcaggtgctcgagctgcagggcctgggtggggtgtac
accgacatctatctgccgttgcacggggaacatcaggcgcacaacgcggcggtggcgttg
gccgcggtcgaggccttcttcggcgcaggggcccagcgccaactcgacgtggacgcggtg
cgggccggcttcgccgccgtcgccagccccggacggatggagcggatgcgcagcgcccca
acggttttcatcgacgccgcgcacaatccggccggggcggccgcgctggcccggacgctg
accgacgagttcgacttcgcgaccttggtcggcgtgctcagcgtgatggccgacaaagac
gtcgacggaatcctggccgcgctggaaccggtgttcgactcgatcgtggtgacccacaac
ggatcgccgcgagctctcgacgtcgaggggttggcgctggcggcccagcagcggttcgga
cccgaccgggtggtcaccgccgagaacatgcgcgacgccatcgacgccgcgaccgccctg
gtggacgcggcccaagcagaggacctgtcttccggcgccggaatcgtcatcaccggatcg
gtcgtcaccgccggcgcagcccgcaccttgttcggacgtgatccggcatga
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