Mandrillus leucophaeus (drill): 105534027 Help Entry 105534027         CDS       T08763                                  Symbol ADCY3 Name (RefSeq) adenylate cyclase type 3   KO K08043   adenylate cyclase 3 [EC:4.6.1.1] Organism mleu  Mandrillus leucophaeus (drill) Pathway mleu00230   Purine metabolism mleu01100   Metabolic pathways mleu01522   Endocrine resistance mleu04015   Rap1 signaling pathway mleu04020   Calcium signaling pathway mleu04022   cGMP-PKG signaling pathway mleu04024   cAMP signaling pathway mleu04062   Chemokine signaling pathway mleu04072   Phospholipase D signaling pathway mleu04114   Oocyte meiosis mleu04211   Longevity regulating pathway mleu04213   Longevity regulating pathway - multiple species mleu04261   Adrenergic signaling in cardiomyocytes mleu04270   Vascular smooth muscle contraction mleu04371   Apelin signaling pathway mleu04540   Gap junction mleu04611   Platelet activation mleu04713   Circadian entrainment mleu04714   Thermogenesis mleu04723   Retrograde endocannabinoid signaling mleu04724   Glutamatergic synapse mleu04725   Cholinergic synapse mleu04727   GABAergic synapse mleu04740   Olfactory transduction mleu04750   Inflammatory mediator regulation of TRP channels mleu04911   Insulin secretion mleu04912   GnRH signaling pathway mleu04913   Ovarian steroidogenesis mleu04914   Progesterone-mediated oocyte maturation mleu04915   Estrogen signaling pathway mleu04916   Melanogenesis mleu04918   Thyroid hormone synthesis mleu04921   Oxytocin signaling pathway mleu04923   Regulation of lipolysis in adipocytes mleu04925   Aldosterone synthesis and secretion mleu04926   Relaxin signaling pathway mleu04927   Cortisol synthesis and secretion mleu04928   Parathyroid hormone synthesis, secretion and action mleu04934   Cushing syndrome mleu04935   Growth hormone synthesis, secretion and action mleu04962   Vasopressin-regulated water reabsorption mleu04970   Salivary secretion mleu04971   Gastric acid secretion mleu04972   Pancreatic secretion mleu04976   Bile secretion mleu05032   Morphine addiction mleu05163   Human cytomegalovirus infection mleu05166   Human T-cell leukemia virus 1 infection mleu05200   Pathways in cancer mleu05207   Chemical carcinogenesis - receptor activation mleu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mleu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105534027 (ADCY3)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105534027 (ADCY3)    04371 Apelin signaling pathway     105534027 (ADCY3)    04020 Calcium signaling pathway     105534027 (ADCY3)    04072 Phospholipase D signaling pathway     105534027 (ADCY3)    04024 cAMP signaling pathway     105534027 (ADCY3)    04022 cGMP-PKG signaling pathway     105534027 (ADCY3)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105534027 (ADCY3)   09144 Cellular community - eukaryotes    04540 Gap junction     105534027 (ADCY3)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105534027 (ADCY3)    04062 Chemokine signaling pathway     105534027 (ADCY3)   09152 Endocrine system    04911 Insulin secretion     105534027 (ADCY3)    04923 Regulation of lipolysis in adipocytes     105534027 (ADCY3)    04912 GnRH signaling pathway     105534027 (ADCY3)    04913 Ovarian steroidogenesis     105534027 (ADCY3)    04915 Estrogen signaling pathway     105534027 (ADCY3)    04914 Progesterone-mediated oocyte maturation     105534027 (ADCY3)    04921 Oxytocin signaling pathway     105534027 (ADCY3)    04926 Relaxin signaling pathway     105534027 (ADCY3)    04935 Growth hormone synthesis, secretion and action     105534027 (ADCY3)    04918 Thyroid hormone synthesis     105534027 (ADCY3)    04928 Parathyroid hormone synthesis, secretion and action     105534027 (ADCY3)    04916 Melanogenesis     105534027 (ADCY3)    04925 Aldosterone synthesis and secretion     105534027 (ADCY3)    04927 Cortisol synthesis and secretion     105534027 (ADCY3)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105534027 (ADCY3)    04270 Vascular smooth muscle contraction     105534027 (ADCY3)   09154 Digestive system    04970 Salivary secretion     105534027 (ADCY3)    04971 Gastric acid secretion     105534027 (ADCY3)    04972 Pancreatic secretion     105534027 (ADCY3)    04976 Bile secretion     105534027 (ADCY3)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     105534027 (ADCY3)   09156 Nervous system    04724 Glutamatergic synapse     105534027 (ADCY3)    04727 GABAergic synapse     105534027 (ADCY3)    04725 Cholinergic synapse     105534027 (ADCY3)    04723 Retrograde endocannabinoid signaling     105534027 (ADCY3)   09157 Sensory system    04740 Olfactory transduction     105534027 (ADCY3)    04750 Inflammatory mediator regulation of TRP channels     105534027 (ADCY3)   09149 Aging    04211 Longevity regulating pathway     105534027 (ADCY3)    04213 Longevity regulating pathway - multiple species     105534027 (ADCY3)   09159 Environmental adaptation    04713 Circadian entrainment     105534027 (ADCY3)    04714 Thermogenesis     105534027 (ADCY3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105534027 (ADCY3)    05207 Chemical carcinogenesis - receptor activation     105534027 (ADCY3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105534027 (ADCY3)    05163 Human cytomegalovirus infection     105534027 (ADCY3)   09165 Substance dependence    05032 Morphine addiction     105534027 (ADCY3)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105534027 (ADCY3)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105534027 (ADCY3)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105534027 (ADCY3) Enzymes [BR:mleu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105534027 (ADCY3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N HNOBA RAP1 Peptidase_S49_N Motif Other DBs NCBI-GeneID:  105534027 NCBI-ProteinID:  XP_011828090 Ensembl:  ENSMLEG00000037538 LinkDB All DBs Position Unknown AA seq 1166 aa AA seqDB search MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLAVAGIGLLLDII LFVLCKKGLLPDRATRRVVPYLLWLLITAQIFSYLGLNFARAHAASDTVGWQVFFVFSFF ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLREILANVFLYLCAIAVG IMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGGSKIEERLYSCVVVPTLRLRWERVHISQ STMDCLKGEFDVEPGDGGSRCDYLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAP ASSKSSSPALIETKEPNGSAHSSGSTSEKPEEQDAQADNPSFPNPRRRLRLQDLADRVVD ASEDEHELNQLLNEALLERESAQVVKKRNTFFLSMRFMDPEMETRYSVEKEKQSGAAFSC SCVVLLCTALVEILIDPWLMTNYVTFVVGELLLLILTICSLAAIFPRAFPKKLVAFSTWI DRTRWARNTWAMLAIFILVMANVVDMLSCLQYYTGPSNATAGMETKGGCLENPKYYNYVA VLSLIATIMLVQVSHMVKLTLMLLVAGAVAAINLYAWGPVFDEYDHRRFREHDLPMVTLE KMQGFTPGLNGTDGLPLVPSKYSMTVMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQK ERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTE ESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFAS SNKEDKSERERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARK PHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFF LKGRDKPAAFPNGPSVTLPHQVVDNS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgccgaggaaccagggcttctctgagcccgagtactcggccgagtactcagccgagtac tccgtcagcctgccctccgaccctgaccgcggggtgggccggacccatgaaatctcggtc cggaactcgggctcctgcctgtgcctgcctcgcttcatgcggctgaccttcgtgccggag tccttggagaacctctaccagacctacttcaaaaggcagcgccacgagaccctgctggtg ctggtggtctttgctgccctctttgactgctacgtggtggtcatgtgtgctgtggtcttc tccagcgacaagctggctccccttgccgtggctggaattggactgctgttggacatcatc ctcttcgtgctctgcaaaaaggggctgctcccggaccgggccacccgcagagtggtgccc tacctgctgtggctgctcataactgcccagatcttctcctacctgggcctgaacttcgcg cgtgcccacgcggccagtgacaccgtgggctggcaggtcttcttcgtcttctccttcttc atcacgctgcccctcagcctcagccccatcgtgatcatctccgtggtctcctgtgtggtg cacaccttggtcctgggggtcactgtggcccagcagcagcaggaggagctgaaggggatg cagctgctgcgcgagatcctggccaacgtcttcctctacctgtgcgccatcgccgtgggc atcatgtcctactacatggctgaccgcaagcaccgcaaggccttcctggaggcccgccag tcgctggaggtgaagatgaacctggaagagcagagccagcagcaggagaacctcatgctt tccatcctgcccaagcatgtggctgacgagatgctgaaagacatgaagaaagacgagagc cagaaggaccagcagcagttcaacaccatgtacatgtaccgccatgagaacgtcagcatc ctctttgccgacatcgtgggctttacccagctgtcttctgcctgcagtgcccaggagctc gtgaagctgctcaacgagctctttgcccgctttgacaagctggcagctaaataccaccag ctgcggattaagatcctgggcgactgctactactgcatctgcggcctgcctgactaccgg gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtat gtgcgggagaagaccaagactggggtggacatgcgtgtgggggtgcacacgggcaccgtg ctggggggcgtcctgggccagaagcgctggcagtacgatgtgtggtcaactgacgtcact gtagccaacaagatggaggccggcggcatccctggtggatcaaagattgaagaaagattg tactcctgtgtcgtggttccaacactgaggctgagatgggagcgtgtgcacatctcccag agcaccatggactgcctgaaaggggagttcgatgtggaaccaggcgatgggggcagccgc tgtgattacctagaagagaagggtattgaaacctacctcatcattgcctccaagccagag gtgaagaaaacagccacccagaatggcctcaatggctcggccctgcccaatggagcacca gcttcctcaaagtccagctcccctgccctcattgagaccaaggagcccaacgggagtgcc cacagcagcgggtccacatcagagaaacccgaggagcaggatgcccaggccgacaacccc tcattccccaacccgcgccggaggctgcgccttcaggacctggctgaccgagtggtggac gcctccgaagacgagcacgagctcaaccagctgctcaacgaggccctgctggagcgagag tctgcccaagtagtaaagaagagaaacaccttcttcctgtccatgcggttcatggacccc gagatggaaacgcgctactcggtggagaaggagaagcagagtggggctgccttcagctgc tcctgcgtcgtcctgctctgcacggctctggtcgagatactcatcgacccctggctaatg acaaactatgtgaccttcgtggtgggggagcttctgctcctcatcctgaccatctgctcc ctggctgccatctttcccagggcctttcctaagaagcttgtggccttctcgacttggatt gaccggacccgctgggccaggaacacctgggccatgcttgccatcttcatcctggtgatg gcaaatgtcgtggacatgctcagctgtctccagtactacacaggacccagcaacgcgaca gcagggatggagacgaagggcggctgcctggagaaccccaagtattacaactacgtggcc gtgctgtctctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacg cttatgctgctcgtcgcgggcgccgtggccgccatcaacctctacgcctggggccccgtc ttcgatgaatacgaccaccggcgttttcgggagcatgacttacctatggtgaccttagag aagatgcagggattcacccctgggctcaacggcactgacgggctgcccctggtgccttcc aagtactccatgacggtgatggtgttcctcatgatgctgagcttctactacttctcccgc cacgtagaaaaactggcacggacacttttcttgtggaagattgaggtccacgaccagaag gaacgtgtctatgagatgcgacgctggaacgaggccttggtcaccaacatgttgcctgag cacgtggcacgccatttcctggggtccaagaagagagatgaggagctgtacagccagacg tatgatgagattggagtcatgtttgcctccctgcccaactttgctgacttctacacagag gagagcatcaacaatggcggtatcgagtgtctgcgtttcctcaatgaaatcatctcggat tttgactctctcctggacaatcccaagttccgggtgatcaccaagatcaaaaccattggc agcacgtatatggcagcttcaggagtcacccctgacgtcaacactaatggctttgccagc tccaacaaggaggacaagtctgagagagaacgctggcagcacctggctgacctggccgac tttgcgctggccatgaaggatacgctcaccaacatcaacaatcagtccttcaataacttc atgctgcgcataggcatgaacaaaggcggggttctggctggggtcatcggagcccggaaa ccacactacgacatctggggcaatacggtcaatgtagccagcaggatggagtccaccggg gtcatgggcaacatccaggtggtagaagaaacccaagtcatcctccgagagtacggcttc cgctttgtgaggcgaggccccatctttgtgaaggggaagggggagctgctgaccttcttc ttgaaggggcgggacaagccagccgccttccccaacggcccctctgtcacactgccccac caggtggtagacaactcctga

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