Mandrillus leucophaeus (drill): 105549604
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Entry
105549604 CDS
T08763
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00010
Glycolysis / Gluconeogenesis
mleu00020
Citrate cycle (TCA cycle)
mleu00620
Pyruvate metabolism
mleu00785
Lipoic acid metabolism
mleu01100
Metabolic pathways
mleu01200
Carbon metabolism
mleu01210
2-Oxocarboxylic acid metabolism
mleu04066
HIF-1 signaling pathway
mleu04922
Glucagon signaling pathway
mleu05230
Central carbon metabolism in cancer
mleu05415
Diabetic cardiomyopathy
Module
mleu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105549604 (PDHA2)
00020 Citrate cycle (TCA cycle)
105549604 (PDHA2)
00620 Pyruvate metabolism
105549604 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105549604 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105549604 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105549604 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105549604 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105549604 (PDHA2)
Enzymes [BR:
mleu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105549604 (PDHA2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
105549604
NCBI-ProteinID:
XP_011849602
Ensembl:
ENSMLEG00000027171
UniProt:
A0A2K5XTP7
LinkDB
All DBs
Position
Unknown
AA seq
388 aa
AA seq
DB search
MLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIEKCDLHLLEEGPPVTTVLTRAEGL
KYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHLITSYRAHG
MCYTRGLSVRSILTELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACK
YKGNNEICLTLYGDGAANQGQIAEAFNMAALWKLPCVFICENNLYAMGTSADRAAASTDY
YKRGNFIPGLKVDGMDVLCVREATKFAADYCRSGKGPILMELQTYRYHGHSMSDPGVSYR
TREEIQEVRSKRDPIMILQDRMVNSKLATVEELKEIGTEVKKEIDDAAQFATSDPEPRLE
ELGHHVYSSDSSFEVRGANPWIKFKSVS
NT seq
1167 nt
NT seq
+upstream
nt +downstream
nt
atgctggccgccttcatctcccgtgtgttgaggcgagttgcccagaagtcagctcgcaga
gtgctggtggcatcccgtaactcctcaaatgacgctacatttgaaattgagaaatgtgat
cttcacctgttggaggagggtccccccgtcactacagtgctcactagggcggaggggctt
aaatactacaggatgatgctgactgttcgccgcatggaattgaaggcagatcagttgtac
aaacagaaattcattcgtggtttctgtcacctgtgcgatggtcaggaagcttgctgcgtg
ggccttgaggctggaataaacccctcggatcacctcatcacatcctatagggctcatggt
atgtgctatactcggggactttctgtccgatccattctcacagagctgacgggaagaaga
ggaggttgtgctaaaggaaaaggaggatcgatgcatatgtataccaagaacttctacggg
ggcaatggcatcgtcggcgcgcagggccccctgggcgctggcattgctctggcctgtaaa
tataagggaaacaatgagatctgtttgactttatatggggatggcgctgcgaatcagggg
cagatagccgaagctttcaatatggcagctttatggaaattaccttgtgttttcatctgt
gagaataacctatatgcaatgggaacatctgctgacagagcagcagccagcactgattac
tacaagaggggcaattttatccctgggctaaaagtcgatggaatggatgttctatgtgtt
cgtgaggcaacaaaatttgcagctgactactgtaggtctggaaaggggcccatactgatg
gagctgcagacctaccgttatcatggacacagtatgagtgatcctggagtcagttatcgt
acacgagaagaaattcaggaagtaagaagtaagagggatcctataatgattctccaagat
agaatggtaaacagcaagctggccactgtggaagaattaaaggaaattgggactgaggtg
aagaaagaaattgatgatgctgcccagtttgctaccagtgatcctgagccacgtctggaa
gaattaggccatcacgtctacagcagtgattcatcttttgaagttcgtggtgcaaatcca
tggatcaagtttaagtccgtcagttaa
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