Mandrillus leucophaeus (drill): 105550780
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Entry
105550780 CDS
T08763
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mleu
Mandrillus leucophaeus (drill)
Pathway
mleu00010
Glycolysis / Gluconeogenesis
mleu00020
Citrate cycle (TCA cycle)
mleu00620
Pyruvate metabolism
mleu00785
Lipoic acid metabolism
mleu01100
Metabolic pathways
mleu01200
Carbon metabolism
mleu01210
2-Oxocarboxylic acid metabolism
mleu04066
HIF-1 signaling pathway
mleu04922
Glucagon signaling pathway
mleu05230
Central carbon metabolism in cancer
mleu05415
Diabetic cardiomyopathy
Module
mleu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mleu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105550780 (PDHA1)
00020 Citrate cycle (TCA cycle)
105550780 (PDHA1)
00620 Pyruvate metabolism
105550780 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105550780 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105550780 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105550780 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105550780 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105550780 (PDHA1)
Enzymes [BR:
mleu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105550780 (PDHA1)
BRITE hierarchy
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1_dh
DUF1117
Motif
Other DBs
NCBI-GeneID:
105550780
NCBI-ProteinID:
XP_011851188
Ensembl:
ENSMLEG00000033588
LinkDB
All DBs
Position
Unknown
AA seq
402 aa
AA seq
DB search
MTLSRRAATEAWRLLGHLKETLGHPRRASWAVRSRRCRQCLCFMRKMLAAVSRVLSGASQ
KPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELK
ADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAE
LTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQGQIFEAYNMAALWKLPCIFICENNRYG
MGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYR
YHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIED
AAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1209 nt
NT seq
+upstream
nt +downstream
nt
atgactctgtcacgtcgcgctgcgactgaggcgtggcgtctgctggggcacctgaaggag
actttgggacaccctcgtcgtgcctcttgggctgtgaggagtcgccgctgccgccagtgc
ctgtgcttcatgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcag
aaaccggcaagcagagtgctggtagcatcccgtaattttgcaaatgatgctacatttgaa
attaagaaatgtgaccttcaccgactggaagaaggccctcctgtcacaacagtgctcacc
agggaggatgggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaa
gcagatcagctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcag
gaagcttgctgtgtgggcctggaagccggcatcaaccccacagaccatctcataacagcc
taccgggctcacggctttaccttcacccggggcctttccgtccgagaaattctcgcagag
cttacaggacgaaaaggaggttgtgctaaagggaaaggaggatcgatgcacatgtatgcc
aagaacttctacgggggcaatggcatcgtgggagcgcagggccagatatttgaagcttac
aacatggcagctttgtggaaattaccttgtattttcatctgtgagaataatcgctatgga
atgggaacatctgttgagagagcagcagccagcactgattactacaagagaggcgatttc
attcctgggctgagagtggatggaatggatatcctgtgcgtccgagaggcgacaaggttt
gctgccgcctattgtagatctgggaaggggcccatcctgatggagctgcagacttatcgt
taccacggacacagtatgagtgatcctggagtcagttaccgtacacgagaagaaattcag
gaagtaagaagtaagagtgaccctattatgcttctcaaggacaggatggtgaacagcaat
cttgccagtgtggaagaactaaaggaaattgatgtggaagtgaggaaggagattgaggat
gctgcccagtttgccacggccgatcctgagccacctttggaggagctgggctaccacatc
tactccagcgacccacctttcgaagttcgtggtgccaatcagtggatcaagtttaagtca
gtcagttaa
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