Myotis lucifugus (little brown bat): 102433066
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Entry
102433066 CDS
T07795
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf00270
Cysteine and methionine metabolism
mlf00480
Glutathione metabolism
mlf01100
Metabolic pathways
mlf01240
Biosynthesis of cofactors
mlf04216
Ferroptosis
Module
mlf_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
102433066 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
102433066 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
102433066 (GCLC)
Enzymes [BR:
mlf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
102433066 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
DUF2811
Motif
Other DBs
NCBI-GeneID:
102433066
NCBI-ProteinID:
XP_014315129
Ensembl:
ENSMLUG00000011240
LinkDB
All DBs
Position
Unknown
AA seq
587 aa
AA seq
DB search
MLVSFDHENKRVQLVLSGEEVLETLQEKGERTNPNHPTLWRPEYGSYMIEGTPGQPYGGT
MSEFNTVEDNMRQRRKEATSLLKENQALCTITSFPRLGCPGFTLPEFKPNPVEGGASRSL
FFPDEAINKHPRFSTLTRNIRHRRGEKVVINAPIFKDKNTPSPFIEKFPEDDEAAKASKP
DHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDV
DCRWGVISASVDDRTREERGLEPLKNNNYRISKSRYDSIDSYLSECGEKYNDIDLTIDKE
IYEQLLQEGIDHLLAQHVAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKP
PPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVNENMKVA
QKRDAVLQGMFYFRKDICKGGNAVVDGCGKAQQSAELAAEEHEEYALMSIDTIINGKEGV
FPGLIPILNCYLENMEVDVDTRCSILNYLKLIKKRASGELMTVAKWMREFIANHPDYKQD
SVITDQINYSLILKCNQIANELCECPELLGPAFRRVRYSGSKTDSSN
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgttggtgtcttttgatcatgaaaataagagagtgcagttggtcctgtctggagaagaa
gtccttgaaactctacaagaaaagggggaaaggacaaacccgaaccaccctacactttgg
agaccagagtatgggagttacatgattgaagggacacctggacagccatacggaggaacc
atgtccgagttcaacacagttgaagacaatatgagacagcgccggaaggaggcaacttct
ttattaaaagaaaatcaggctctttgcacaataacttcatttcccagattaggctgtcct
gggttcaccctgcctgagttcaaacccaacccagtcgaaggaggagcttccaggtccctc
ttctttcccgatgaagcaataaacaagcatccccgctttagcaccctaaccagaaatatc
cggcacaggagaggagaaaaggtagtcatcaatgcaccaatatttaaagataagaacaca
ccgtctccgtttatagaaaaatttcctgaggatgacgaggcggccaaggcttcaaagcca
gatcacatctacatggatgccatgggatttgggatgggcaattgctgtcttcaggtaacg
ttccaagcctgcagcatttccgaggctagatacctgtatgatcagttggccactatctgc
ccaattgtcatggctttgagtgctgcgtctcctttttaccgaggctatgtgtcagacgtt
gattgtcgctggggcgtgatttctgcatctgtagatgatagaactcgggaggagagagga
ctggagccactgaagaacaataactataggattagtaaatcccgatatgattcaatagac
agttatctgtctgagtgtggagagaaatacaatgacatcgacttgacaatagataaagaa
atctacgagcagctgttgcaggaaggcattgaccacctcctggcccagcatgttgctcat
ctctttatcagagacccgctgactctgtttgaagagaaaatacacctggatgatgccaat
gagtctgaccattttgagaacattcagtccacaaattggcagacaatgagatttaagcct
cctcctccaaactcagacattggatggagagtggaattccggcccatggaggttcagtta
acagacttcgagaactcggcatatgtggtgtttgtggtgctgctcacgagagttatcctt
tcctacaaattagattttctcattccgctgtcaaaggtaaatgaaaacatgaaagtcgca
cagaaacgagatgctgtcctgcagggaatgttctatttcaggaaagatatttgcaaaggt
ggcaacgctgtggtggacggctgtggcaaggcccagcagagcgcggagctggccgcagag
gagcacgaggagtacgccctgatgagcatagacaccatcatcaatgggaaggaaggcgtg
tttcctgggctgatcccgattctgaactgctacctggaaaacatggaagtggatgtggac
accagatgtagcattctgaactacctgaagctgattaagaagagagcatctggagaacta
atgacagtcgccaaatggatgagggagtttatcgcaaaccatcccgactacaagcaagac
agtgtaataactgatcaaataaactatagtcttattttaaagtgcaaccaaattgcaaat
gaattatgtgaatgcccagagttacttggaccagcatttaggagagtaagatatagcgga
agtaaaacggactcttccaactag
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