Myotis lucifugus (little brown bat): 102433201
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Entry
102433201 CDS
T07795
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
mlf
Myotis lucifugus (little brown bat)
Pathway
mlf00310
Lysine degradation
mlf01100
Metabolic pathways
mlf05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
mlf00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
102433201 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
102433201 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mlf03036
]
102433201 (DOT1L)
Enzymes [BR:
mlf01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
102433201 (DOT1L)
Chromosome and associated proteins [BR:
mlf03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
102433201 (DOT1L)
HMT complexes
Dot1-containing complex
102433201 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
102433201
NCBI-ProteinID:
XP_014322004
Ensembl:
ENSMLUG00000004399
LinkDB
All DBs
Position
Unknown
AA seq
1730 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLK
GSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVP
ESKAAVPADTSVDSGAEEEKAATTAIKKPSPSKARKKKLNKKGRKLAGRKRGRPKKMSTA
NPERKPKKNPTALDLLHAQTVSQTATPSPQDAYKSPHSPFYQLPPSVQRHPPDQLLLAPT
PPALQKLLESFKIQYLQFLAYTKTPQYKASLQQLLDQEKEKNARLLGAAQQLFGHCQAQK
EEIKKLFQQKLDELGVKALTYSDLIQAQKEISAHNQQLREQTEQLEKDNRELRSQSLQLL
KARCEELKLDWSTLSLENLLKEKQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLK
SCVPPDDAVSLHLRGKGGLGRELEAEPSRLHLELDCSKFSLPHFSSMSPELSMNGHAASY
ELCNTLSRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLALPDYTRLSPAKLV
LRRHLSQDHTASGKTPAGELHPRTEHAKENGLPYQSPGLANGIKLSPQDPRPSSPVALQM
TGEKGSEKGLKERAYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPNRAEKRSTP
SPVPQTRESSSTLEKQMGANAHGAGSNAAGSKSLTLGPTGFYAGSVAISGALAGSPAPLA
PGVEPPVFDESSSSGSLFTTMGSRSSTPQHPQLLVQPRNSGPASPTHQLCVSPRLGAAQG
PLPDGSKGDLPSEVGFSDPESEAKRRIIFTISAGASSTKQSPSNKHSPLPGGARGDSSQS
HGQDSRKRGRRKRASAGTPNLSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVNNINQPL
EITAISSPESSLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEPGSEDEQGST
RIERKIATISLESKSPPKTLENGGSLVGRKPMPSSEPINSSKWKSTFSPIADLGLAKATD
SPLQASSALSQNSLFAFRPTLEELSSVDAKLATHPRKSFPGALSGAGGLSPISNPPNGFA
FSGSLAADLSLHSFSDGASLSHKAPEVASLGAPLSFSAPRGKESSTEPGPFVNKRQLDGL
GGPKGEGVKGREGEVSLPVCTPSDKASSHGKVGKGRDREPDFKNGHNLFISAAAVPPGGL
LSGPGLTTAASSASGTAPSSQTHRPFLGTFAPGPQFALGPMSLQANLGSSVLQSLFTSVP
AAAGLVHVSSAATRLTNSHAMGSFSSGVAGGAVGGIFNHTVPSASTHPFGASFGSGAACR
STTLSLTPMQAVASTPASSFQALSSVETRQPPPQPPLPLGRPPAGPPALHAPPPPPNAAL
PPAPALLPANSEPVLLQNLAPLPANQAFLPASSAASLPPANASLSIKLASLPHKVSRPSF
MVHHQPLPGLALAQASPMIPQASSTGPSAVWVSLGMPPPYAARLAGVKPR
NT seq
5193 nt
NT seq
+upstream
nt +downstream
nt
atgggggagaagctggagctgaggctcaagtcgcccgtgggggccgagcccgccgtctat
ccgtggccgctgccggtctacgacaaacaccacgatgctgctcatgaaatcatcgagacc
atccgatgggtctgtgaggaaatcccagacctcaagctcgctatggagaattatgtccta
atcgactacgacaccaaaagcttcgaaagcatgcagaggctctgtgataagtacaaccgg
gccatcgacagcatccaccagctgtggaagggaaccacgcagcccatgaagctgaatacg
cggccatccaatgggctcctgcggcacatcctgcagcaggtttacaaccactcagtgacg
gaccctgagaagctcaacaactacgagcccttctccccagaggtatatggggagacctcc
tttgacctggtcgcacagatgattgatgagatcaagatgaccgaggacgacctgtttgtg
gacctgggaagtggagtgggccaggtcgtgctgcaagtcgccgcggccaccaactgcaaa
catcactacggagtcgagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaaaga
ggtgatttcctctcggaggagtggagagagcggatcgccaacacaagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgatttgcaaacatg
aaggaaggtggcagaattgtgtcctcgaagccctttgcacctctgaacttcagaataaac
agtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggagctctcgcccctgaag
ggctcagtgtcgtggacggggaagcccgtctcctactacctgcacaccatcgaccgcacc
atacttgaaaactatttttctagtctgaaaaatccaaaactcagggaggaacaagaggca
gctaggcgccggcagcagcgagaaaacaagagtaatacaaccacccccacgaaggtgcct
gagagcaaggcggctgtgcctgcggacacctctgtggattctggtgctgaggaagagaaa
gcagcgaccaccgctatcaagaagccatccccctccaaagcacggaagaagaagctgaac
aagaagggccggaagctggctggacggaagcgcggacgtcccaagaagatgagcactgcg
aaccctgagcgtaagcccaagaagaaccctactgcactggacctcctgcacgcccagact
gtgtcccagacggcgacgccctcaccacaagatgcatacaagtcacctcacagcccattt
tatcagctacctcccagcgtgcagcggcacccccctgaccagctgttgctggcacccacc
ccgcccgcactgcagaagctgctagagtccttcaagattcagtacctgcagttcctggca
tacacgaagacccctcagtacaaggccagcctgcagcagctgctggaccaggagaaggag
aagaatgcccgattgctgggtgccgcacagcagctgttcggtcactgccaggcccagaaa
gaagaaataaagaagctttttcagcagaaactggatgagttgggagtgaaggcgctgacc
tacagtgacctgatccaagctcagaaagagatctcggctcacaaccagcagctgcgagag
cagacggagcagctggagaaggacaacagggagctgagaagccagagcctgcagctgctg
aaggctcggtgtgaggagctgaagttggactggtccacactgtccctggagaacctgcta
aaggagaagcaggccctgaagagccagatctccgagaaacagaggcactgcctggagctg
cagattagcatcgtggagctggaaaagagccagcggcagcaggagctcctgcaactcaag
tcctgcgtgccgcctgatgatgctgtgtccctgcacctacgagggaaaggtggcctgggc
cgagaactggaggcggaacccagccggctgcaccttgaactggactgctccaaattctcc
ctgccccacttcagtagcatgagcccagagctctccatgaatggccacgcggccagctat
gagctctgcaacacactgagtcggccctcgtccaagcagaacaccccccagtacctggcc
tctccactggaccaggaggtggtgccatgtactcccagccacagcggccggccccggctc
gagaagctgtctggcttggccttgccagactacaccaggctctccccggccaagctggtg
ctgagacgccacctgagccaggaccacactgccagtggcaagacacctgctggtgagcta
cacccacgaactgagcacgccaaggagaatggccttccataccagagcccgggcctcgcc
aatggcatcaagctgagtcctcaggacccacggccctcatcccctgtggccttacagatg
acaggagaaaaaggcagtgagaagggtctgaaggagcgcgcctatgccagcagtggggag
gccatcaccagcctacccgtcagcattccactcagcactgtgcagcccagcaagctgccc
gtcagcatccccctggccagcgtggtgttgcccaaccgtgccgagaagagaagcaccccc
agtcctgtgcctcagacccgagagtcctcgtccacacttgaaaagcagatgggtgctaat
gcccatggtgctgggagcaacgctgctgggagcaaaagcctcaccctggggcccacaggc
ttctatgcaggctcagtcgccatcagtggggccctggcaggcagcccggccccactcgct
cctggagttgagccccctgtcttcgatgagtcctccagctcggggagcctcttcaccacc
atgggctcccgcagctccaccccacagcatcctcaactgctagtgcaaccccggaactcc
ggtccagcctcgcccacgcaccagctctgcgtcagcccccgactcggcgctgcccagggc
ccactccctgatgggagcaaaggggaccttccctctgaggttggcttctcagatccagag
agcgaggccaagaggaggatcatcttcaccatctcagctggtgccagcagcaccaagcag
tcaccttccaacaagcacagccctctgcctgggggtgctcgtggagacagcagtcagagc
catgggcaggacagtcgaaagcggggcaggaggaagcgggcatcagcggggacccccaat
ctgagctcaggcgtgtcccccaagcgccgggccttgccatccgtcgccggcctcttcact
cagtcttcagggtctcccctcaacctgaactctatggtcaacaacattaaccaacctttg
gaaatcacagccatctcgtcccctgagagctccctgaagagctcccctgtaccttaccag
gacaacgaccagccacccgtgctcaagaaagagaagcccctgagccagaccaatggagcc
cactactccccactgacctcagatgaggagccgggctctgaggacgagcaaggcagcacc
agaattgagagaaaaattgcaactatctccttagaaagcaaatctcctccgaaaaccttg
gaaaatggtggcagcctggtaggaaggaagccgatgccctccagcgagcccatcaacagc
agcaagtggaagtccaccttctcacccatcgctgaccttggcctggccaaggctactgac
agcccgctacaggccagctccgctctgagccagaactccctgttcgcttttcggcccacc
ctagaggagctcagctcagttgatgccaagctggccacccaccccaggaagagctttccg
ggtgcactgtcgggggctggcgggctgagtcccatcagcaacccccccaacggctttgcc
ttcagcgggagcctggctgccgacctcagtttacacagtttcagtgatggtgcttctctc
tcccacaaggcccctgaggtggccagcctgggcgcccccctgagcttttccgccccgagg
ggtaaggagagcagcacggagcctggcccctttgtgaacaagaggcagctggatggactg
ggtggcccgaagggtgagggggtcaagggcagggagggagaagtcagcttgcccgtgtgc
acaccctcagacaaggcctcatcacatggcaaggtgggcaagggccgggaccgcgagcct
gatttcaaaaatggccacaatctcttcatttctgccgctgccgtgcctcctgggggcctc
ctcagcgggccaggcctcaccacagcagcgtcctcagcaagcggcacagccccctcctcc
cagacacaccggcccttcctgggcacttttgcaccgggcccacagtttgccttgggcccc
atgtccctgcaggccaacttaggctcatctgtgctgcagtccttgttcacctctgtgccg
gctgctgctggcctagtgcacgtctcatccgctgcaaccagactgaccaactctcatgcc
atgggcagcttttcctccggtgtggcaggtggtgcagttggaggtatctttaaccacacg
gtgccttccgcctccactcatccgtttggagccagtttcggcagcggggctgcttgtcgc
agcaccacgctgagcttaaccccgatgcaggcggtggccagtacccccgcctcttccttt
caggccctgtcctctgtggagaccaggcagcccccaccccagcctcctctgcccctgggt
cggccccctgcggggccaccagcacttcacgcgcccccccctcctcctaacgctgccttg
cctcctgctcctgcactgcttcctgctaactctgagcctgtgctcctgcagaatcttgcg
cccctcccggctaaccaagctttcttacctgcctcctctgccgcctctctgcctcctgct
aacgcctctctatctatcaagctcgcctccctcccacacaaggtctcccgcccctccttc
atggtgcaccaccagcccctgcctggactggctctggcccaggcctcacccatgatccca
caggccagctccacggggccatccgccgtgtgggtttcccttggcatgccgcctccttat
gccgcgcgccttgcgggggttaagccgcgataa
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integrated database retrieval system
