KEGG   Mustela lutreola (European mink): 131810080
Entry
131810080         CDS       T09578                                 
Symbol
TPH1
Name
(RefSeq) tryptophan 5-hydroxylase 1
  KO
K00502  tryptophan 5-monooxygenase [EC:1.14.16.4]
Organism
mlk  Mustela lutreola (European mink)
Pathway
mlk00380  Tryptophan metabolism
mlk00790  Folate biosynthesis
mlk01100  Metabolic pathways
mlk04726  Serotonergic synapse
Module
mlk_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:mlk00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    131810080 (TPH1)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    131810080 (TPH1)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    131810080 (TPH1)
Enzymes [BR:mlk01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.4  tryptophan 5-monooxygenase
     131810080 (TPH1)
SSDB
Motif
Pfam: Biopterin_H ACT TH_ACT ACT_4 zf-C2HE DUF5370 DUF262
Other DBs
NCBI-GeneID: 131810080
NCBI-ProteinID: XP_058993671
LinkDB
Position
1:complement(247716577..247736795)
AA seq 444 aa
MIEDNKENKDHSLERGRATLIFSLKNEVGGLIKALKIFQEKHVNLLHIESRKSKRRNSEF
EIFVDCDINREQLNDIFHLLKSHTNVLSVNPPDNFTVKEDGMETVPWFPKKVSDLDHCAN
RVLMYGSELDADHPGFKDNVYRKRRKYFADLAMNYKHGDPIPKVEFTEEEIKTWGTVFRE
LNKLYPTHACREYLKNLPLLSKYCGYREDNIPQLEDVSNFLKERTGFSIRPVAGYLSPRD
FLSGLAFRVFHCTQYVRHSSDPLYTPEPDTCHELLGHVPLLAEPSFAQFSQEIGLASLGA
SEESVQKLATCYFFTVEFGLCKQDGQLRVFGAGLLSSISELKHSLSGHAKVKPFDPKITC
KQECLITTFQDVYFVSESFEDAKEKMREFTKTIKRPFGVKYNPYTRSVQILKDTKSITSA
MNELQHDLDVVSDALAKVSRQPIS
NT seq 1335 nt   +upstreamnt  +downstreamnt
atgattgaagacaataaggaaaataaagaccattccttagaaagagggagagcaaccctc
attttttccttgaagaatgaagttggtggactcataaaagccctgaaaattttccaggag
aagcatgtgaacctgttacatatcgagtctcggaaatcaaagagaagaaactcagaattt
gagatttttgtggactgtgatatcaacagagaacagttgaatgacatttttcatctgttg
aagtcccatactaacgttctctctgtgaatccaccagataattttactgtgaaggaagat
ggtatggaaactgttccttggtttccaaagaaggtttctgacctggaccattgtgccaac
agagttctgatgtatggatctgaactggatgccgatcatcctggcttcaaagacaatgtt
taccgtaaaagacggaaatattttgcagacttggctatgaactataaacatggagacccc
attcccaaagttgaattcactgaagaggagattaagacctggggaactgtgttccgagag
ctcaacaaactttacccaacccatgcctgcagagagtatctcaaaaacttacctttgctt
tctaaatattgtggataccgggaagataatatcccccaattggaagatgtctcaaacttt
ttaaaagagcgcactggtttttccatccgtcccgtggctggttacctgtcaccaagagat
ttcttatcaggtttagccttccgggttttccactgcacacagtacgtgagacacagttct
gaccctctctataccccagagccagatacttgccatgagctcttaggtcatgtccccctt
ttggctgaacctagttttgctcagttctcccaagaaattggcctggcttcccttggagct
tcagaggagtctgttcaaaaactcgcaacgtgctactttttcactgtggagtttggtctc
tgtaagcaagacgggcagctgcgagtctttggtgcggggttactttcttctatcagtgaa
cttaagcattcactttctggacatgctaaagtaaagccctttgatcccaagattacctgc
aaacaggagtgtctcatcacaacttttcaggatgtctactttgtatctgaaagctttgaa
gatgcaaaggagaagatgagagaatttaccaaaacaattaagcgtccatttggagtgaag
tacaatccatacacacggagtgttcagatcttgaaagacaccaagagcataaccagcgcc
atgaacgagctgcagcatgatcttgatgtcgtcagtgatgcccttgcgaaggtcagcaga
cagccgatcagctga

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