Mustela lutreola (European mink): 131821262
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Entry
131821262 CDS
T09578
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mlk
Mustela lutreola (European mink)
Pathway
mlk00010
Glycolysis / Gluconeogenesis
mlk00020
Citrate cycle (TCA cycle)
mlk00620
Pyruvate metabolism
mlk00785
Lipoic acid metabolism
mlk01100
Metabolic pathways
mlk01200
Carbon metabolism
mlk01210
2-Oxocarboxylic acid metabolism
mlk04066
HIF-1 signaling pathway
mlk04922
Glucagon signaling pathway
mlk05230
Central carbon metabolism in cancer
mlk05415
Diabetic cardiomyopathy
Module
mlk_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mlk00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
131821262 (PDHA1)
00020 Citrate cycle (TCA cycle)
131821262 (PDHA1)
00620 Pyruvate metabolism
131821262 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
131821262 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
131821262 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
131821262 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
131821262 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
131821262 (PDHA1)
Enzymes [BR:
mlk01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
131821262 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
MIF4G_like
Motif
Other DBs
NCBI-GeneID:
131821262
NCBI-ProteinID:
XP_059013214
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All DBs
Position
X:15184591..15199321
Genome browser
AA seq
389 aa
AA seq
DB search
MRKMLAAVSRVLGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDG
LKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAH
GFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALAC
KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTD
YYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSY
RTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPL
EELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtctctcgcgtgttgggcgtcgcccagaagccggcaagc
agagtgctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaatgc
gatcttcaccggctggaggagggccctcctgtcaccacagtgctcaccagggaggacggg
ctcaagtactacaggatgatgcagacggtccgccggatggagttaaaggcagatcagctg
tacaagcagaagattattcgtggtttctgtcatttgtgtgatggtcaggaagcttgttgt
gtgggcttggaggctggcataaatcccacagaccatcttatcacagcctatcgggctcat
ggctttaccttcactcgtgggctttctgtccgagaaattctcgcagagcttacaggacga
agaggaggctgtgctaaagggaaaggtggatcgatgcacatgtacgccaagaacttctac
gggggcaacggcatcgtcggcgcgcaggtgcccttgggagcggggattgccttggcctgt
aagtataacgggaaggatgaggtctgtctgactttgtatggcgacggtgctgctaatcag
ggtcagatatttgaagcttacaacatggcagctttgtggaaactgccgtgtattttcatc
tgtgagaacaaccgctatggaatgggaacatctgttgagagagcagcggccagcacggac
tactacaagagaggcgacttcatccctgggctgagggtagatggaatggacatcttgtgt
gtccgggaggcaacaaggtttgcagctgcctactgtagatctggaaaggggcccatactg
atggagctacagacctaccgttaccacggacacagcatgagcgaccctggcgtcagttac
cgtacccgagaagagattcaggaagtacgaagtaagagtgaccctatcatgctgctcaag
gatagaatggtgaacagcaatctggccagcgttgaagaattaaaggaaattgatgttgaa
gtgaggaaggaaattgaggatgctgcccagtttgccactgcggatcccgaaccgcctttg
gaagagctgggttaccacatttacagcagcgacccgccttttgaagttcggggtgccaat
cagtggatcaagtttaagtccatcagttaa
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