Mustela lutreola (European mink): 131838820 Help Entry 131838820         CDS       T09578                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism mlk  Mustela lutreola (European mink) Pathway mlk00230   Purine metabolism mlk01100   Metabolic pathways mlk01522   Endocrine resistance mlk04015   Rap1 signaling pathway mlk04022   cGMP-PKG signaling pathway mlk04024   cAMP signaling pathway mlk04062   Chemokine signaling pathway mlk04072   Phospholipase D signaling pathway mlk04114   Oocyte meiosis mlk04211   Longevity regulating pathway mlk04213   Longevity regulating pathway - multiple species mlk04261   Adrenergic signaling in cardiomyocytes mlk04270   Vascular smooth muscle contraction mlk04371   Apelin signaling pathway mlk04540   Gap junction mlk04611   Platelet activation mlk04713   Circadian entrainment mlk04714   Thermogenesis mlk04723   Retrograde endocannabinoid signaling mlk04724   Glutamatergic synapse mlk04725   Cholinergic synapse mlk04727   GABAergic synapse mlk04742   Taste transduction mlk04750   Inflammatory mediator regulation of TRP channels mlk04911   Insulin secretion mlk04912   GnRH signaling pathway mlk04913   Ovarian steroidogenesis mlk04914   Progesterone-mediated oocyte maturation mlk04915   Estrogen signaling pathway mlk04916   Melanogenesis mlk04918   Thyroid hormone synthesis mlk04921   Oxytocin signaling pathway mlk04923   Regulation of lipolysis in adipocytes mlk04924   Renin secretion mlk04925   Aldosterone synthesis and secretion mlk04926   Relaxin signaling pathway mlk04927   Cortisol synthesis and secretion mlk04928   Parathyroid hormone synthesis, secretion and action mlk04934   Cushing syndrome mlk04935   Growth hormone synthesis, secretion and action mlk04961   Endocrine and other factor-regulated calcium reabsorption mlk04962   Vasopressin-regulated water reabsorption mlk04970   Salivary secretion mlk04971   Gastric acid secretion mlk04972   Pancreatic secretion mlk04976   Bile secretion mlk05032   Morphine addiction mlk05163   Human cytomegalovirus infection mlk05166   Human T-cell leukemia virus 1 infection mlk05200   Pathways in cancer mlk05207   Chemical carcinogenesis - receptor activation mlk05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mlk00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     131838820 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     131838820 (ADCY6)    04371 Apelin signaling pathway     131838820 (ADCY6)    04072 Phospholipase D signaling pathway     131838820 (ADCY6)    04024 cAMP signaling pathway     131838820 (ADCY6)    04022 cGMP-PKG signaling pathway     131838820 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     131838820 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     131838820 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     131838820 (ADCY6)    04062 Chemokine signaling pathway     131838820 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     131838820 (ADCY6)    04923 Regulation of lipolysis in adipocytes     131838820 (ADCY6)    04912 GnRH signaling pathway     131838820 (ADCY6)    04913 Ovarian steroidogenesis     131838820 (ADCY6)    04915 Estrogen signaling pathway     131838820 (ADCY6)    04914 Progesterone-mediated oocyte maturation     131838820 (ADCY6)    04921 Oxytocin signaling pathway     131838820 (ADCY6)    04926 Relaxin signaling pathway     131838820 (ADCY6)    04935 Growth hormone synthesis, secretion and action     131838820 (ADCY6)    04918 Thyroid hormone synthesis     131838820 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     131838820 (ADCY6)    04916 Melanogenesis     131838820 (ADCY6)    04924 Renin secretion     131838820 (ADCY6)    04925 Aldosterone synthesis and secretion     131838820 (ADCY6)    04927 Cortisol synthesis and secretion     131838820 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     131838820 (ADCY6)    04270 Vascular smooth muscle contraction     131838820 (ADCY6)   09154 Digestive system    04970 Salivary secretion     131838820 (ADCY6)    04971 Gastric acid secretion     131838820 (ADCY6)    04972 Pancreatic secretion     131838820 (ADCY6)    04976 Bile secretion     131838820 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     131838820 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     131838820 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     131838820 (ADCY6)    04727 GABAergic synapse     131838820 (ADCY6)    04725 Cholinergic synapse     131838820 (ADCY6)    04723 Retrograde endocannabinoid signaling     131838820 (ADCY6)   09157 Sensory system    04742 Taste transduction     131838820 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     131838820 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     131838820 (ADCY6)    04213 Longevity regulating pathway - multiple species     131838820 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     131838820 (ADCY6)    04714 Thermogenesis     131838820 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     131838820 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     131838820 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     131838820 (ADCY6)    05163 Human cytomegalovirus infection     131838820 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     131838820 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     131838820 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     131838820 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     131838820 (ADCY6) Enzymes [BR:mlk01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      131838820 (ADCY6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  131838820 NCBI-ProteinID:  XP_059041483 LinkDB All DBs Position 8:65958036..65979854 Genome browser AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRRGTRTGGFCTPRYMSCLREAQPPSPSPAAPP RCPWQDEAFIRRGGPGKGTELGLRAVALGFEDTEATAAVGVADVVPDGSPRRRWSCWRRL AQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPAPPQPAYVA LLACAATLFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSVGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQLGANMLLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYL KEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLVPRWAPDRAFSRTKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS RKVDPRFGAYVACALLVFCFICFIQLLVFPHSTVMLGIYAGIFLLLLITVLTCAVSSCGS LFPKALRRLSRSIVRSRAHSTVVGIFSVLLVFTSAIANMFTCNHTPIRNCAARMLNVTPA DITTCHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNMLLSLLASSVFLHISSIGKLAMV FVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGPDCPAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQAGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPPS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcgtggtttagtggcctcctggtccccaaagtggatgaacggaaaacagcctggggt gagcgcaatgggcagaagcgtccgcgccgtgggacccggacaggtggcttctgcacgccc cgctacatgagctgcctccgggaggcccagccccctagtcccagccccgccgctcccccg cggtgcccctggcaggatgaggccttcatccggaggggtggcccgggcaagggcactgag ctggggctgcgggcggtggccctgggctttgaggacacagaggcaacggcagcagtgggg gtggccgatgtggtgcccgacgggagccccaggcgtcggtggtcgtgctggcggcgtctg gcccaggtgttccagtccaagcagttccgctcggccaagctggagcgcctgtaccagcgg tacttcttccagatgaaccagagcagcctgacgctgctgatggccgtgctggtgctgctc acagcggtgctgctggccttccacgcggcgcctgcccctccgcagcctgcatatgtggcc ctgctggcctgcgccgccaccctcttcgtggcgctcatggtggtgtgcaaccggcacagc ttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcagctgtg caggtggggggcgccctggcggctgacccccgcagcccctctgttggcctctggtgcccc gtgtttttcgtctacatcacctacacgctcctgcccatccgcatgcgggcggctgtcttc agtggcctgggcctctccaccctgcatctgatcttggcctggcaactcaaccgcggggac gccttcctctggaagcagctgggcgccaacatgctgctgttcctctgcaccaacgtcatt ggcatctgcacacactacccggcggaggtgtctcagcgccaggcctttcaggagacccgt ggttatatccaggcccggctgcacctgcagcacgagaaccggcagcaggaacggctgctg ctgtccgtgttgccccagcatgttgccatggagatgaaagaagatatcaacacaaagaaa gaagacatgatgttccacaagatctacatccagaagcatgacaatgtcagcatcctgttt gcggacattgaaggcttcaccagcctggcatcccagtgcaccgcacaggagctggtcatg accctgaacgagctctttgcccggtttgacaagctggctgcggaaaatcactgcctgagg atcaagatcttaggggactgttactactgtgtgtcggggctgccggaggcccgggcagac catgcccactgctgtgtggagatgggggtggacatgatcgaggccatctcgctggtgcgc gaggtgacaggtgtgaacgtgaacatgcgcgtgggcatccacagcgggcgtgtgcactgt ggtgtcctcggcctgcggaaatggcagttcgacgtgtggtccaatgacgtgacgctggcc aaccacatggaggcagggggccgggccggccgtatccacatcacccgggccacgctgcag tacctgaatggggactatgaggtggagccaggccgtggcggtgagcggaacgcatacctc aaggagcagcacatcgagaccttcctcatcctgggagccagccagaaacggaaagaggag aaggccatgctggccaagctgcagcggacgcgggccaactccatggaagggctggtgcca cgctgggcgcctgaccgcgccttctcccggaccaaggactccaaggctttccgtcagatg ggcattgatgattccagcaaggacaaccggggtgcccaagatgccctgaaccccgaggat gaagtagatgagttcctgggccgcgccatcgatgcccgcagcatcgaccagctacggaag gaccatgtgcgccgcttcctgctcactttccagagagaggatcttgaaaagaagtactcg cggaaggtggacccccgcttcggagcctacgtcgcctgtgcgctgttggtcttctgcttc atctgctttatccagcttctcgtcttcccacactccaccgtgatgcttggcatctatgcc ggtatcttcctgctgttgctgatcactgtgctgacctgtgccgtgtcctcctgtggctct ctcttccccaaggccctgcgccgtctttcccgcagtattgtccgctctcgggcacacagc actgtggttggcatcttttcagtcttgcttgtgttcacctctgccatcgccaacatgttc acctgcaaccacacccccatacgaaactgcgcagcccggatgctaaatgtgacacccgct gacatcaccacctgtcacctgcagcagctcaattactctctgggcctggacgctcccctg tgtgagggcaccgcacccacctgcagcttccctgagtacttcgttgggaacatgctgctg agtctcttggccagctctgtcttcctgcacatcagcagcattggaaagctggccatggtc tttgtcctggggctcatctatttggtgctgcttctgctgggccccccagccaccatcttt gacaactacgacttgctgcttggtgtccatggcttggcttcttccaatgagactttcgat gggccggactgcccagctgccgggagggtggcgctcaagtacatgacccccgtgattctg ctggtgtttgcgctggctctgtatctgcatgcccagcaggtggaatcaactgcccggctg gacttcctttggaaactgcaggcaacaggggagaaggaggagatggaggaactgcaggca tacaaccggaggctgctgcataatattctgcccaaggacgtggctgcccacttcctggcc cgggagcgtcggaacgatgagctctactaccagtcgtgtgaatgtgtggccgtcatgttt gcctccattgccaacttttctgagttctatgtggagctggaggcaaacaatgagggcgtc gagtgcctgcggctgctcaatgagatcattgctgactttgatgagatcatcagcgaggag cgcttccggcagctggagaagatcaagacgatcgggagcacctacatggcggcctcagga ctgaacgccagcacctacgatcaggccggccgctcccacatcactgccctggcagactat gccatgcggctcatggagcagatgaaacacatcaacgagcactccttcaacaatttccag atgaagattgggctgaacatgggcccagttgtggcaggcgtcattggggctcggaagccg cagtatgacatctgggggaacacagtgaatgtctctagccgtatggacagcacgggtgtc cctgaccgaatccaggtgaccacggacttgtaccaggttctagctgccaaaggctaccag ctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctc aatgggggcccccccagttag

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