Mirounga leonina (Southern elephant seal): 117997743
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Entry
117997743 CDS
T07472
Symbol
MAPK12
Name
(RefSeq) mitogen-activated protein kinase 12
KO
K04441
p38 MAP kinase [EC:
2.7.11.24
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01522
Endocrine resistance
mlx04010
MAPK signaling pathway
mlx04015
Rap1 signaling pathway
mlx04068
FoxO signaling pathway
mlx04071
Sphingolipid signaling pathway
mlx04114
Oocyte meiosis
mlx04148
Efferocytosis
mlx04218
Cellular senescence
mlx04261
Adrenergic signaling in cardiomyocytes
mlx04370
VEGF signaling pathway
mlx04380
Osteoclast differentiation
mlx04550
Signaling pathways regulating pluripotency of stem cells
mlx04611
Platelet activation
mlx04613
Neutrophil extracellular trap formation
mlx04620
Toll-like receptor signaling pathway
mlx04621
NOD-like receptor signaling pathway
mlx04622
RIG-I-like receptor signaling pathway
mlx04625
C-type lectin receptor signaling pathway
mlx04657
IL-17 signaling pathway
mlx04658
Th1 and Th2 cell differentiation
mlx04659
Th17 cell differentiation
mlx04660
T cell receptor signaling pathway
mlx04664
Fc epsilon RI signaling pathway
mlx04668
TNF signaling pathway
mlx04670
Leukocyte transendothelial migration
mlx04714
Thermogenesis
mlx04722
Neurotrophin signaling pathway
mlx04723
Retrograde endocannabinoid signaling
mlx04728
Dopaminergic synapse
mlx04750
Inflammatory mediator regulation of TRP channels
mlx04912
GnRH signaling pathway
mlx04914
Progesterone-mediated oocyte maturation
mlx04917
Prolactin signaling pathway
mlx04926
Relaxin signaling pathway
mlx04932
Non-alcoholic fatty liver disease
mlx04933
AGE-RAGE signaling pathway in diabetic complications
mlx04935
Growth hormone synthesis, secretion and action
mlx04936
Alcoholic liver disease
mlx05014
Amyotrophic lateral sclerosis
mlx05020
Prion disease
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05132
Salmonella infection
mlx05133
Pertussis
mlx05135
Yersinia infection
mlx05140
Leishmaniasis
mlx05142
Chagas disease
mlx05145
Toxoplasmosis
mlx05152
Tuberculosis
mlx05161
Hepatitis B
mlx05163
Human cytomegalovirus infection
mlx05167
Kaposi sarcoma-associated herpesvirus infection
mlx05169
Epstein-Barr virus infection
mlx05170
Human immunodeficiency virus 1 infection
mlx05171
Coronavirus disease - COVID-19
mlx05205
Proteoglycans in cancer
mlx05208
Chemical carcinogenesis - reactive oxygen species
mlx05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
mlx05415
Diabetic cardiomyopathy
mlx05417
Lipid and atherosclerosis
mlx05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
117997743 (MAPK12)
04015 Rap1 signaling pathway
117997743 (MAPK12)
04370 VEGF signaling pathway
117997743 (MAPK12)
04668 TNF signaling pathway
117997743 (MAPK12)
04068 FoxO signaling pathway
117997743 (MAPK12)
04071 Sphingolipid signaling pathway
117997743 (MAPK12)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
117997743 (MAPK12)
09143 Cell growth and death
04114 Oocyte meiosis
117997743 (MAPK12)
04218 Cellular senescence
117997743 (MAPK12)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
117997743 (MAPK12)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
117997743 (MAPK12)
04613 Neutrophil extracellular trap formation
117997743 (MAPK12)
04620 Toll-like receptor signaling pathway
117997743 (MAPK12)
04621 NOD-like receptor signaling pathway
117997743 (MAPK12)
04622 RIG-I-like receptor signaling pathway
117997743 (MAPK12)
04625 C-type lectin receptor signaling pathway
117997743 (MAPK12)
04660 T cell receptor signaling pathway
117997743 (MAPK12)
04658 Th1 and Th2 cell differentiation
117997743 (MAPK12)
04659 Th17 cell differentiation
117997743 (MAPK12)
04657 IL-17 signaling pathway
117997743 (MAPK12)
04664 Fc epsilon RI signaling pathway
117997743 (MAPK12)
04670 Leukocyte transendothelial migration
117997743 (MAPK12)
09152 Endocrine system
04912 GnRH signaling pathway
117997743 (MAPK12)
04914 Progesterone-mediated oocyte maturation
117997743 (MAPK12)
04917 Prolactin signaling pathway
117997743 (MAPK12)
04926 Relaxin signaling pathway
117997743 (MAPK12)
04935 Growth hormone synthesis, secretion and action
117997743 (MAPK12)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
117997743 (MAPK12)
09156 Nervous system
04728 Dopaminergic synapse
117997743 (MAPK12)
04723 Retrograde endocannabinoid signaling
117997743 (MAPK12)
04722 Neurotrophin signaling pathway
117997743 (MAPK12)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
117997743 (MAPK12)
09158 Development and regeneration
04380 Osteoclast differentiation
117997743 (MAPK12)
09159 Environmental adaptation
04714 Thermogenesis
117997743 (MAPK12)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
117997743 (MAPK12)
05208 Chemical carcinogenesis - reactive oxygen species
117997743 (MAPK12)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
117997743 (MAPK12)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
117997743 (MAPK12)
05161 Hepatitis B
117997743 (MAPK12)
05171 Coronavirus disease - COVID-19
117997743 (MAPK12)
05163 Human cytomegalovirus infection
117997743 (MAPK12)
05167 Kaposi sarcoma-associated herpesvirus infection
117997743 (MAPK12)
05169 Epstein-Barr virus infection
117997743 (MAPK12)
09171 Infectious disease: bacterial
05132 Salmonella infection
117997743 (MAPK12)
05135 Yersinia infection
117997743 (MAPK12)
05133 Pertussis
117997743 (MAPK12)
05152 Tuberculosis
117997743 (MAPK12)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
117997743 (MAPK12)
05140 Leishmaniasis
117997743 (MAPK12)
05142 Chagas disease
117997743 (MAPK12)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
117997743 (MAPK12)
05020 Prion disease
117997743 (MAPK12)
05022 Pathways of neurodegeneration - multiple diseases
117997743 (MAPK12)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
117997743 (MAPK12)
05418 Fluid shear stress and atherosclerosis
117997743 (MAPK12)
05415 Diabetic cardiomyopathy
117997743 (MAPK12)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
117997743 (MAPK12)
04932 Non-alcoholic fatty liver disease
117997743 (MAPK12)
04933 AGE-RAGE signaling pathway in diabetic complications
117997743 (MAPK12)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
117997743 (MAPK12)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
117997743 (MAPK12)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.24 mitogen-activated protein kinase
117997743 (MAPK12)
Protein kinases [BR:
mlx01001
]
Serine/threonine kinases: CMGC group
MAPK family [OT]
117997743 (MAPK12)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
APH
Kdo
UvrD_C
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
117997743
NCBI-ProteinID:
XP_034841921
LinkDB
All DBs
Position
Unknown
AA seq
367 aa
AA seq
DB search
MSSPPPARRGFYRQEVTKTAWEVRAVYQDLQPVGSGAYGAVCSAVDSRTGAKVAIKKLYR
PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
KHEKLSEDRIQFLVYQMLKGLKYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSAGCIMAEMITGKTLFKGSDHLDQLKEIMK
VTGTPPADFVQRLQSADAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAERRV
TAAEALTHPYFESLQDTEDEPKAQKYDESFDDMDRTLDEWKRVTYKEVLSFKPPRQLGTK
VSKETAL
NT seq
1104 nt
NT seq
+upstream
nt +downstream
nt
atgagctctccgccgcccgcccgcaggggcttttaccgccaggaggtgaccaagacggct
tgggaggtgcgcgccgtgtaccaggacctgcagcccgtgggctccggcgcctacggcgcg
gtgtgctcggccgtggacagccgcactggcgccaaggtggccatcaagaagctgtaccgg
cccttccagtcggagctcttcgccaagcgcgcctaccgcgaactgcgcctcctcaagcac
atgcgccacgagaacgtcatcgggctgctggacgtgttcacccctgatgaaaccctggat
gatttcacagacttttacctggtgatgccattcatggggactgacctgggcaagctcatg
aagcacgagaagctgagtgaggaccgaatccagttccttgtctaccagatgctgaagggg
ctaaagtacatccatgctgctggcatcatccatagggacctgaagcccggcaatctggca
gtgaatgaggactgtgagctgaagatcctggacttcggcctggcgaggcaggcagacagc
gagatgactgggtatgtggtgactcggtggtaccgggcgcctgaggtcatcttgaattgg
atgcgctacacacagacagtggatatctggtcggcgggctgcatcatggcggagatgatt
acagggaagacgctgttcaagggcagtgaccacctggaccagctgaaggagatcatgaag
gtgacagggacgcctcccgctgactttgtgcagaggctgcagagtgctgatgcaaagaac
tacatgaagggcctccccgagttggagaagaaggattttgcgtccatcctgactaatgca
agtcctctggctgtgaacctcctggagaaaatgcttgtgctagatgcagagcggcgggtg
actgcggccgaggcgctgacccacccctacttcgagtcactgcaggacacggaggacgag
cccaaggcccagaagtacgatgagtcctttgatgatatggaccgcacgctggacgagtgg
aaacgtgtcacatataaagaagtgctcagcttcaagcctccccggcagctggggaccaag
gtctccaaggagacggccctgtga
DBGET
integrated database retrieval system