Mirounga leonina (Southern elephant seal): 118000829
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Entry
118000829 CDS
T07472
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01524
Platinum drug resistance
mlx04010
MAPK signaling pathway
mlx04071
Sphingolipid signaling pathway
mlx04141
Protein processing in endoplasmic reticulum
mlx04210
Apoptosis
mlx04530
Tight junction
mlx04668
TNF signaling pathway
mlx04714
Thermogenesis
mlx04722
Neurotrophin signaling pathway
mlx04932
Non-alcoholic fatty liver disease
mlx04936
Alcoholic liver disease
mlx05010
Alzheimer disease
mlx05012
Parkinson disease
mlx05014
Amyotrophic lateral sclerosis
mlx05016
Huntington disease
mlx05017
Spinocerebellar ataxia
mlx05022
Pathways of neurodegeneration - multiple diseases
mlx05208
Chemical carcinogenesis - reactive oxygen species
mlx05417
Lipid and atherosclerosis
mlx05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
118000829 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
118000829 (MAP3K5)
04668 TNF signaling pathway
118000829 (MAP3K5)
04071 Sphingolipid signaling pathway
118000829 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
118000829 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
118000829 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
118000829 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
118000829 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
118000829 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
118000829 (MAP3K5)
05012 Parkinson disease
118000829 (MAP3K5)
05014 Amyotrophic lateral sclerosis
118000829 (MAP3K5)
05016 Huntington disease
118000829 (MAP3K5)
05017 Spinocerebellar ataxia
118000829 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
118000829 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
118000829 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
118000829 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
118000829 (MAP3K5)
04932 Non-alcoholic fatty liver disease
118000829 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
118000829 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118000829 (MAP3K5)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
118000829 (MAP3K5)
Protein kinases [BR:
mlx01001
]
Serine/threonine kinases: STE group
STE11 family
118000829 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
118000829
NCBI-ProteinID:
XP_034846640
LinkDB
All DBs
Position
Unknown
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPFAEGGSSRRGGAAVAAEDEESQLPPPPPGSFWNVETAAAPGTGCP
AATSGSSATRCRGNSSSGGGRRTTVAYVINEASQGQLVVAESEALQSLREACETVGATLE
TLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDNN
SDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
EKALDVMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFLDTESRDHGASWFKKAFESEPS
LQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRGTEEGDCES
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRACANDLLVDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVGDTSGSSEYGSVSPDAELKADPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHIT
TLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGINQVQVVLFSFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDDHEERPLNQTIR
RPHAVIEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKIETNRLLEELVRKEKELQA
LLHRAIEEKDQEIKHLKLKSQPIDIPGLPICPRGSPGTNTEESELTEWLREKGADEDTIS
RFLAEDYSLEDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDTQT
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgccgaagcgggcgagggcatcactttctcggtgccacccttcgccgagggcggc
agcagccggaggggaggagcggctgtggcggccgaggacgaggagagccagctgccgccg
ccgccgccgggcagcttctggaacgtagagactgccgccgcccctggcaccggttgtccc
gctgccacctctgggagcagcgccacccggtgccggggcaactctagtagcggaggcggc
cgacggaccacggtggcatatgtgatcaacgaagcgagtcaggggcagctggtggtggcc
gagagcgaggccctgcagagcctgcgggaggcgtgcgagacggtgggcgccacactggag
accctgcattttggtaaactggactttggggaaaccaccgtgctggaccgtttttacaat
gcagatattgctgtggtggagatgagtgatgccttccgacagccgtccttgttttaccac
cttggagtgagagaaagtttcagcatggccaacaacatcatcctctactgtgataataat
tcagactctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactggg
aactacacatttgtcccttacatgatcactccacataacaaggtctactgctgtgatagc
agcttcatgaaggggttgacagagctcatgcaaccgaacttcgagctgcttcttggaccc
atttgcttacctcttgtggatcgtttcatccaacttctgaaggtggcacaagcaagttct
agccagtatttccgggaatctatactcaatgatatcaggaaagctcgaaatttatacact
ggtaaagaattggcagctgaattggcaagaattcggcaacgagtagataatattgaagtc
ttgacagcagatattgtcataaacctcttactttcctacagagatatccaggactatgat
tctattgtgaagctggtagagacgttagaaaagctgccaacctttgatttggcttcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaatctccctggagataga
gaaaaagctcttgatgttatgatcccgctggtgcaaagtgaagggcaggttgcttcagat
atgtattgcctagttggtcgaatctacaaagacatgtttttggactctaatttcctggac
actgagagtagagaccatggagcttcttggttcaaaaaggcatttgaatctgagccatca
ctacagtcaggaattaattacgcggttcttctcctggcggctgggcatcagtttgaatct
tcctttgagctccggaaagttggagtgaagctgagtagcctccttggtaaaaagggaaac
ttagaaaaactccagagctactgggaagttggattttttctgggcgccagtgtcctggcc
aatgaccacatgagagtcatccaagcatctgaaaagctttttaaactgaagacaccggca
tggtacctcaagtcaattgtagagacaattttgatatataagcattttgtgaaactgact
accgagcagcctgtggccaaacaggagctcgtggacttctggatggatttcctggttgag
gccacaaagaccgatgttaccgtagttaggtttccagtattaatattagaaccaaccaaa
atctatcaaccttcatatttgtctatcaacaatgaagttgaagaaaagacgatatctatt
tggcatgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggagtgagtatttctaaatttgaagaacgatgctgttttctttatgtgcttcat
aattccgatgatttccaaatctatttctgtacagaactgcactgtaaaaagttttttgaa
atggtgaacaccatcactgaagagaaggggagaggcacggaggaaggagattgtgaaagt
gactccctggagtatgactatgaatatgatgagaatggtgacagagtcgttttagggaaa
ggcacttacgggatcgtctacgcaggccgagacctgagcaaccaggtcagaatcgctata
aaggaaatcccagagagagatagcagatactcccagcccctacatgaagaaatcgcattg
cataaacatctgaagcacaaaaatattgtccagtatctgggctctttcagtgagaatggt
ttcatcaaaatcttcatggagcaggtcccaggaggaagtctttctgctctccttcgttcc
aaatggggcccattgaaggacaatgagcaaacaattggcttttatacaaagcagatactt
gaaggattaaaatacctccatgacaatcagatagtccaccgggatataaagggcgacaac
gtgttgattaatacctatagtggtgttctcaagatctcggacttcggaacatcaaagagg
ctcgctggcataaacccatgtactgaaacttttactggtacccttcagtatatggcaccg
gaaatcatagacaaaggaccacgaggctacgggaaagcagcagacatctggtctttgggc
tgcaccatcatcgaaatggccacagggaaaccacctttttatgaactgggagaaccacaa
gcagctatgttcaaggtgggaatgtttaaagtccacccggagatcccagagtccatgtca
gcagaggccaaggcattcatactgaagtgttttgaaccagaccccgacaagagagcctgt
gctaacgacttgcttgttgatgagttcttaaaagtttcaagcaaaaagaaaaagacacaa
cctaagctttcagccctttcagccggatcaaatgagtatctccgaagcatatccctgcct
gtgcctgtcctggtgggggacacgagtggcagcagcgagtacggctctgtttctcccgat
gcggagttaaaagcggaccccttctctttcaaaacgagagccaagtcctgcggagaaaga
gacgtgaaaggaatacggacactctttctgggcattccagatgaaaattttgaagaccac
agcgccccgccttcccctgaagaaaaagattctggattctttatgctgaggaaggacagt
gagagacgggccacccttcataggatcctgacggaagaccaagacaaagttgtgagaaac
ttaatggaatctttggctcagggggccgaagaacctaaactaaaatgggaacatatcaca
accctcatcgcaagcctcagagaatttgtgagatccacggaccgaaaaatcatcgccacc
acactgtccaagctgaagctagaacttgacttcgacagccacggcattaaccaagtccag
gtggtgctcttcagttttcaagatgctgtcaataaagttcttcggaatcataatatcaaa
ccacactggatgtttgccttagacagtatcatccgaaaggcggtgcagacggccattacc
attctggttccagaactgaggccacatttcagcctcgcgtctgagagtgacaccgctgat
caagaagacttggatgcagaagatgaccatgaggaacggcctttgaaccaaactatccga
agacctcatgctgtcattgaagatgctgtggctacctcaggggtgagcacgctcagttct
actgtatcccacgactcccaaaatgctcaccggtccctcaatgtgcaacttggaaggatg
aaaatagaaactaatagattactggaagaattggttcggaaagagaaagaattacaagca
ctacttcatcgagctattgaagaaaaagaccaagaaattaaacacctgaagcttaagtcc
caaccaatagatattcctggattgcccatatgcccccggggttctcctggcacaaatact
gaagagtctgaacttactgagtggctgagagaaaagggagctgatgaagacactataagt
cggtttttggctgaggattattcactagaggatgttctctactatgttacacgtgatgat
ttaaaatgcctcagactaaggggagggatgctttgcacactgtggaaggccatcaccgac
ttccgagacacacagacttga
DBGET
integrated database retrieval system
