Mirounga leonina (Southern elephant seal): 118010186
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Entry
118010186 CDS
T07472
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx00010
Glycolysis / Gluconeogenesis
mlx00020
Citrate cycle (TCA cycle)
mlx00620
Pyruvate metabolism
mlx00785
Lipoic acid metabolism
mlx01100
Metabolic pathways
mlx01200
Carbon metabolism
mlx01210
2-Oxocarboxylic acid metabolism
mlx04066
HIF-1 signaling pathway
mlx04922
Glucagon signaling pathway
mlx05230
Central carbon metabolism in cancer
mlx05415
Diabetic cardiomyopathy
Module
mlx_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
118010186 (PDHA2)
00020 Citrate cycle (TCA cycle)
118010186 (PDHA2)
00620 Pyruvate metabolism
118010186 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
118010186 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
118010186 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
118010186 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
118010186 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
118010186 (PDHA2)
Enzymes [BR:
mlx01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
118010186 (PDHA2)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
118010186
NCBI-ProteinID:
XP_034860263
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MKKMLAAAVSRVLSGVAQKPASRVLVASRNHCNDATFEIKKCDLYRLEEGPPVTTVLSRE
DGLKYYRMMQTIRRMELKADQLYRQKFIRGFCHLCDGQEACCVGLEAGINPTDHVITSYR
AHGLCYTRGLSVRAILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQGPLGAGVAL
ACKYKGRKEVCLALYGDGAANQGQIFEAYNMAALWKLPCVFVCENNLYGMGTSAERAAAS
TDYYKRGHFIPGLRVDGMDVLCVREATRFAADYCRSEKGPVVMELQTYRYHGHSMSDPGV
SYRSRQEIQNVRSKSDPIMLLRDRMANSKLATVEEFKEIDVEVRKAIDDAAHFATTDPEP
PLEELGHHIYCDNPPFEVRGASQWIKFKSLS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaagaagatgctcgcggccgcggtctcccgcgtgttgtccggcgttgcccagaagccc
gctagcagagtgctggtggcatcccgtaaccattgcaatgatgccacatttgaaattaag
aaatgtgacctttatcgattagaagagggcccgcctgtcacaacagtgctcagccgggag
gatgggcttaaatactacaggatgatgcagactattcgccgcatggaactgaaggcagat
cagctgtatagacaaaaatttattcgtgggttctgtcacttgtgcgatggccaggaagct
tgttgtgtgggcctggaggccgggataaatcccaccgatcatgtcatcacatcctatcgg
gctcacggcttgtgctatactcgtggcctttctgtccgagcaattcttgcagaactgaca
ggacgaaggggaggctgtgctaaaggaaaagggggatctatgcacatgtatgcaaagaac
ttctatgggggcaacggcattgtcggcgcccaggggcccctgggagctggtgtggccctg
gcctgtaaatataagggcagaaaggaggtctgtttggccctgtacggggatggtgctgcg
aatcagggtcagatatttgaagcttacaatatggctgctctgtggaaattaccttgtgtt
ttcgtctgtgagaataacctctacggaatgggcacgtctgctgagagagcagcagcaagc
actgattactacaagagaggacactttatccccggactaagggtggatgggatggatgtt
ctgtgtgttcgggaggcaacgaggtttgcggcggactactgcagatctgaaaaggggccc
gtagtgatggagctgcagacataccgttatcatggacacagcatgagtgaccctggagtt
agttaccgctcgcgacaagaaattcagaatgtgagaagcaagagtgatcctattatgctt
ctccgagatagaatggcaaacagtaagcttgccactgttgaagaattcaaggaaattgat
gtagaagtgaggaaagcaattgacgatgcagcccactttgctacaactgatcctgaacca
cctttggaagaattaggtcatcacatctattgcgataatccaccttttgaagttcgtggc
gcaagtcagtggatcaagtttaagtccctcagttaa
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