Mirounga leonina (Southern elephant seal): 118016129
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Entry
118016129 CDS
T07472
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01521
EGFR tyrosine kinase inhibitor resistance
mlx01522
Endocrine resistance
mlx04012
ErbB signaling pathway
mlx04066
HIF-1 signaling pathway
mlx04140
Autophagy - animal
mlx04150
mTOR signaling pathway
mlx04151
PI3K-Akt signaling pathway
mlx04152
AMPK signaling pathway
mlx04211
Longevity regulating pathway
mlx04213
Longevity regulating pathway - multiple species
mlx04350
TGF-beta signaling pathway
mlx04371
Apelin signaling pathway
mlx04666
Fc gamma R-mediated phagocytosis
mlx04714
Thermogenesis
mlx04910
Insulin signaling pathway
mlx04931
Insulin resistance
mlx05163
Human cytomegalovirus infection
mlx05165
Human papillomavirus infection
mlx05170
Human immunodeficiency virus 1 infection
mlx05200
Pathways in cancer
mlx05205
Proteoglycans in cancer
mlx05207
Chemical carcinogenesis - receptor activation
mlx05210
Colorectal cancer
mlx05212
Pancreatic cancer
mlx05221
Acute myeloid leukemia
mlx05224
Breast cancer
mlx05225
Hepatocellular carcinoma
mlx05226
Gastric cancer
mlx05231
Choline metabolism in cancer
mlx05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
118016129 (RPS6KB2)
04350 TGF-beta signaling pathway
118016129 (RPS6KB2)
04371 Apelin signaling pathway
118016129 (RPS6KB2)
04066 HIF-1 signaling pathway
118016129 (RPS6KB2)
04151 PI3K-Akt signaling pathway
118016129 (RPS6KB2)
04152 AMPK signaling pathway
118016129 (RPS6KB2)
04150 mTOR signaling pathway
118016129 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
118016129 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
118016129 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
118016129 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
118016129 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
118016129 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
118016129 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118016129 (RPS6KB2)
05205 Proteoglycans in cancer
118016129 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
118016129 (RPS6KB2)
05231 Choline metabolism in cancer
118016129 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
118016129 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
118016129 (RPS6KB2)
05212 Pancreatic cancer
118016129 (RPS6KB2)
05225 Hepatocellular carcinoma
118016129 (RPS6KB2)
05226 Gastric cancer
118016129 (RPS6KB2)
05221 Acute myeloid leukemia
118016129 (RPS6KB2)
05224 Breast cancer
118016129 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
118016129 (RPS6KB2)
05163 Human cytomegalovirus infection
118016129 (RPS6KB2)
05165 Human papillomavirus infection
118016129 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
118016129 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
118016129 (RPS6KB2)
01522 Endocrine resistance
118016129 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mlx01001
]
118016129 (RPS6KB2)
Enzymes [BR:
mlx01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
118016129 (RPS6KB2)
Protein kinases [BR:
mlx01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
118016129 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
118016129
NCBI-ProteinID:
XP_034869288
LinkDB
All DBs
Position
Unknown
AA seq
483 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEPELSPSDVCPLAESRAAGLEPVGHCEEVELTETSVNLGPERI
GPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNI
LESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLAL
GHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILV
RSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLTLPPYLTPDARDLVKK
FLKRNPGQRIGGGPGDAADVQRHPFFRHINWDDLLARRIDPPFRPSLQSEEDVSQFDSHF
TRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSLKEGFSLQPKLRSPRRLHSSPRTPV
SPLKFSPFEGFRPGSGPLEPSEPPLPPLLPPPPPPPPSSTAPLPIRPPSGTKKSKRGRGR
PGR
NT seq
1452 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtttgacctggacctggagacggaggaaggcagcgagggcgagccagag
ttgagcccctcggacgtgtgtccccttgccgagtcgagggcggctggcctggagcctgtg
ggacactgtgaggaggtggagctgactgagaccagtgtgaacctaggccctgagcgcatc
gggccccactgctttgagctgctgcgtgtgctgggcaaggggggctatggcaaggtgttc
caagtgcgaaaggtgcagggcaccaacttgggcaaaatatatgccatgaaagtcctgagg
aaggccaaaattgtgcgcaacgccaaggacacagcacacacgcgggctgaacggaacatt
ctagagtcagtgaagcaccccttcattgtggaactggcctatgccttccagactggtggc
aaactctacctcatcctcgagtgtctcagtggcggtgagctcttcacgcatctggagcga
gagggcatcttcctggaagacacggcctgtttctacctggcagagatcacactggccctg
ggccatctccactcccaaggcatcatctaccgggacctcaaacctgagaacatcatgctc
aacagccagggccacatcaaactgacagactttggactctgcaaggagtcgatccatgag
ggcgccgtcacccatactttctgtggcaccattgagtacatggcccctgagattctggta
cgcagtggccacaaccgggcggtggactggtggagcctgggggccctgatgtatgacatg
ctcactggatcgccacccttcactgcagagaaccggaagaaaaccatggacaagatcatc
aaagggaagctgacgctgcccccctacctcaccccggatgcccgggaccttgtcaaaaag
tttctgaagcggaatcctggccaacggatcgggggtggccctggggatgctgctgatgtg
cagaggcaccccttcttccggcacattaattgggacgacctcctggctcgccgcatcgac
ccccctttcaggccttctctgcagtcagaggaggacgtgagccagtttgactcccacttc
acgcggcagacgccagtggacagtcccgatgatacggccctcagcgagagcgccaaccag
gccttcctgggcttcacatatgtggctccctccgtcctggacagcctcaaggagggcttc
tccttgcagcccaagctgcgctcccccaggcgcctccacagcagcccccggaccccggtc
agcccgctgaagttctcgccctttgagggattccggcccggctctggcccactggagccc
tcggagccccctctacctcctctcctgccgccgccgccgccaccgccaccctcgagcact
gctcccctccccatccgacccccctcagggaccaagaagtctaagaggggccgtgggcgc
ccagggcgctag
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