Mirounga leonina (Southern elephant seal): 118017516
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Entry
118017516 CDS
T07472
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1 isoform X1
KO
K02599
Notch 1
Organism
mlx
Mirounga leonina (Southern elephant seal)
Pathway
mlx01522
Endocrine resistance
mlx04330
Notch signaling pathway
mlx04658
Th1 and Th2 cell differentiation
mlx04919
Thyroid hormone signaling pathway
mlx05020
Prion disease
mlx05165
Human papillomavirus infection
mlx05200
Pathways in cancer
mlx05206
MicroRNAs in cancer
mlx05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
mlx00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
118017516 (NOTCH1)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
118017516 (NOTCH1)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
118017516 (NOTCH1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
118017516 (NOTCH1)
05206 MicroRNAs in cancer
118017516 (NOTCH1)
09162 Cancer: specific types
05224 Breast cancer
118017516 (NOTCH1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
118017516 (NOTCH1)
09164 Neurodegenerative disease
05020 Prion disease
118017516 (NOTCH1)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
118017516 (NOTCH1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
EGF
hEGF
EGF_CA
EGF_2
Ank_2
Ank
Notch
NOD
NODP
Ank_4
Ank_5
Ank_3
EGF_3
JAG1-like_EGF2
Motif
Other DBs
NCBI-GeneID:
118017516
NCBI-ProteinID:
XP_034871326
LinkDB
All DBs
Position
Unknown
AA seq
2567 aa
AA seq
DB search
MPPLLAPLLCLALLPALAARGLRCSQPSESCLNGGKCEVFPNGTEACVCSGAFVGQRCQA
PSPCLSAPCKNAGTCHVVDRGGLVDYICTCRLGFSGPLCLTPQDNACLSTPCRNGGTCDL
LTLTEYKCRCPPGWSGKTCQQADPCASNPCANGGQCLPFEASYICGCPHGFHGPTCRQDV
NECSQNPRLCQNGGTCHNEVGSYRCTCRTTHTGPHCELPYVPCSPSPCQNGGTCRPTGDT
THECACLPGFTGQNCEENVDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDEC
QLMPNACQNGGTCHNSHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYC
ECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLG
ANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECISNPCQNEATCLDQIGEFQCICM
PGYEGVHCEVNTDECASSPCLQNGRCLDKINEFLCECSTGFTGHLCQYDVDECASTPCKN
GAKCLDGPNTYTCVCTEGYTGPHCEVDIDECDPDPCHYGVCKDGVATFTCLCRPGYTGHH
CESNINECHSQPCRHGGTCQDRDNAYLCSCLKGTTGPNCETNLDDCVSSPCDSGTCLDKI
DGYECACEPGYTGSMCNVNIDECAGNPCHHGGTCEDGVNSFTCRCPEGYHGPTCLSEVNE
CSSDPCIHGACRDSLNGYKCDCDPGWSGANCDVNNDECESNPCANGGACRDMTSGYVCTC
REGFSGPNCQTNINECASNPCLNQGSCIDDVAGYKCNCPLPYTGATCEVVLAPCAPGPCR
NGGVCKESEDYESFSCICPTGWQGQTCEVDINECVKSPCRNGASCQNTNGGYRCRCRAGY
TGHNCETDVDDCRPNPCHNGGSCTDGVNTAFCDCLPGFRGPFCEEDINECASNPCRHGAN
CTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQ
HDVNECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQSLVRWCDSSPCKNGGRCWQTNT
RYRCECHSGWTGLYCDVPNVSCEVAAQRQDINVTHLCRNGGLCMDAGNTHHCRCQAGYTG
SYCEDQVDECSPSPCQNGATCTDYPGGYSCECVAGYHGVNCSEEINECVSQPCQNGGTCI
DLTNTYKCSCPRGTQGVHCEVNVDDCSPPIDPVSRGPKCFNNGTCVDQVGGYSCTCPPGF
VGERCEGDVNECLSNPCDARGTQNCVQRVNDFYCECRAGHTGRRCESVINGCKGRPCQNG
GTCAVASNTARGFICKCPAGFEGATCENDARACGSRRCLNGGTCISGPRSPTCLCLGAFT
GPECQFPAGSPCVGGNPCYNQGSCEPTAESPFYRCLCPAKFNGLLCHILDYSFGGGLGLD
IPPPQIEEACELPECREEAGNKVCSLACNNHACGWDGGDCSLNFNDPWQNCSQSLQCWKY
FSNGRCDSQCNSVGCLFDGFDCQRAEGQCNPLYDQYCKDHFGDGHCDQGCNSAECEWDGL
DCAEHVPERLAAGALVLVVLTPPAQLRNNSLHFLRELSRLLHTNVVFKRDAHGQPMIFPY
YGREEELRKHPIKRAADGWAAPGALLDRVEAALLPRGLAGRRRRELDPMDIRGSIVYLEI
DNRQCVQSSSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPPQLHFMYVA
VAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNA
SDGALMDDNQNEWGDEDLEAKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRVSAMAP
TPPQGEADTDCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL
HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQIL
IRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNN
VEAAVVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDI
AQERMHHDIVRLLDEYSLVRSPQLHGPALGGAPTLSPPLCSPNGYLGNLKPAVPGKKARK
PSTKGLACGGKEAKDLKARRKKSQDGKGCLLDSSSVLSPVDSLESPHGYLSDVASPPLLS
SPFQQSPSVPLSHLPGMPDAHLGVGHLSVAAKPEMAALGAGGRLAFEAGPPRLSHLPVAS
STSAVLGTAGAGGGGGAVNFAVGGAAGLNGQCEWLSRLQNGLVPNQYNPLRGNVASGPLS
TQAPALQHGMMGPLHAGLSTTAALSQMMSYQALPNTRLAGQPHLVQTQPLQQVQQQQQNL
QLQQPGLQTQQNLQPPNVQQPQGLPPQPHLSVSSAAGGHLGRSFLGGEPSQADVQPLGPS
SLAVHTILPQDSQALPTALPATLAPPMTTAQFLTPPSQHSYSSSPADNTPSHQLQVPEHP
FLTPSPESPDQWSSSSPHSHVSDWSEGISSPPTSTQSHIAHIPEALK
NT seq
7704 nt
NT seq
+upstream
nt +downstream
nt
atgccgccgctcctggcgcccctgctctgcctggcgctgctgcccgcgctcgccgcacga
ggcctgcgatgttcccagcccagtgagagctgcttgaatggcgggaagtgtgaagtgttc
cccaacggcaccgaagcctgtgtctgcagcggggccttcgtgggccagcgatgccaggca
cccagcccctgcctcagcgccccctgcaagaacgccgggacgtgccacgtggtggaccgc
ggaggcctggtggactacatctgcacctgccgcctgggcttctccgggcccctctgcctg
acgccccaagacaacgcctgcctctccaccccctgtcgcaacgggggcacctgtgacctg
ctcacgctcaccgagtacaagtgccgctgccccccgggctggtcagggaagacgtgccag
caggccgacccgtgcgcctccaacccctgtgccaatggcggccagtgcctgcccttcgag
gcttcgtacatctgcggctgcccgcacggcttccacggccccacctgcaggcaggacgtg
aatgagtgcagccagaaccccaggctctgccaaaacgggggcacctgccacaacgaggtc
ggctcctaccgctgcacctgccgcaccacccacaccggcccccactgcgagctgccctac
gtgccctgcagcccctccccctgccagaacgggggcacctgccgccccacgggggacacc
acccacgagtgcgcctgcctgccaggcttcaccggccagaactgcgaggagaacgtggat
gactgtcccggcaacaactgcaagaacggaggtgcttgcgtggacggcgtaaacacctac
aactgccgctgtcccccagagtggacaggtcagtactgcaccgaggacgtggacgagtgc
cagctcatgcccaacgcctgccagaatggcggcacctgccacaacagccacgggggctat
aactgcgtgtgcgtcaacggctggacgggcgaggactgcagcgagaacatcgacgactgt
gccagcgccgcctgcttccacggcgccacctgccacgaccgcgtggcctccttctactgc
gagtgtccccacggccgcacgggcctgctctgccacctgaacgacgcctgcatcagcaac
ccttgcaacgagggttccaactgcgacaccaaccccgtgaacggcaaagccatctgcacc
tgcccctcggggtacacggggccggcctgcagccaggacgtggacgagtgctcgctgggt
gccaacccctgtgagcacgcgggcaagtgcatcaacacgctgggctccttcgagtgccag
tgtctacaaggctacaccggcccccgctgcgagatcgacgtcaatgagtgcatctcaaac
ccgtgtcagaatgaggccacctgcctggaccagatcggggagttccagtgcatctgcatg
cccggctacgagggcgtgcactgtgaggtcaacacggacgagtgtgccagtagcccctgt
ctccagaacggccgctgcctggacaaaatcaacgagtttctgtgcgagtgctccacgggc
ttcaccggacatctatgtcagtatgacgtggacgagtgtgcaagcacgccctgcaagaac
ggcgccaagtgcctggacgggcccaacacctacacctgcgtgtgcacagaaggctacacg
gggccgcactgcgaggtggacatcgacgagtgcgaccccgatccctgccactacggggtg
tgcaaggacggggtggccaccttcacctgcctgtgccggccgggctacacgggccaccac
tgcgagagcaacatcaacgagtgccacagccagccctgccggcacggcggcacctgccag
gaccgcgacaacgcctatctctgctcctgcctcaaggggaccacaggacccaactgtgag
acgaacctggacgactgcgtcagcagcccctgcgactcgggcacgtgcctggacaagatc
gacggctacgagtgtgcgtgcgagcccggctacacggggagcatgtgcaacgtgaacatc
gacgagtgcgcgggcaacccctgccaccacgggggtacctgtgaggacggtgtcaacagc
ttcacgtgccgctgccccgagggctaccacggccccacgtgcctgtccgaggtcaacgag
tgcagcagcgacccctgcatccacggggcctgccgggacagcctcaacgggtacaagtgt
gactgtgaccccgggtggagcggggccaactgtgacgtgaacaacgacgagtgtgagtcc
aacccgtgtgcgaacggcggtgcctgccgagacatgaccagcggctacgtgtgcacctgc
cgcgagggcttcagtggccccaactgccaaaccaacatcaacgagtgtgcgtccaacccg
tgcctgaaccagggctcgtgcatcgatgacgtggccgggtacaagtgcaactgtccgctg
ccctacacaggagccacgtgcgaggtggtgctggccccgtgcgcccccggcccctgcaga
aacgggggcgtgtgcaaagagtctgaggactatgagagtttctcctgcatctgccccacg
ggctggcaaggacagacctgtgaggtcgacattaacgagtgtgtgaagagcccatgccgc
aacggggcctcgtgccagaacaccaacggcggctaccgctgccgctgccgcgcaggctac
acggggcacaactgcgagacggacgtggacgactgccggccaaacccatgccacaacggc
ggttcctgcaccgacggcgtcaacaccgctttctgcgactgcctgcctggcttccggggg
cccttctgcgaggaggacatcaacgagtgcgccagcaacccatgccgccacggggccaac
tgcacggactgcgtggacagctacacctgcacctgccccgcgggcttcagcgggatccac
tgtgagaacaacacgcccgactgcacagagagctcttgctttaatggcggcacctgtgtg
gacggcatcaactccttcacctgcctgtgtccgccgggcttcacgggcagctactgtcag
cacgacgtcaacgagtgcgactcgcggccctgcctgcatggtggcacctgccaggacagc
tacgggacctacaagtgcacctgcccgcagggctacacaggcctcaactgccagagcctc
gtgcgctggtgcgactcctcgccctgcaagaacggcggcaggtgctggcagaccaacacg
cggtaccgctgcgagtgccacagcggctggactggcctctactgcgacgtgcccaacgtg
tcctgtgaggtggccgcccagcgccaagacatcaacgtcacccacctgtgccggaacggg
gggctctgcatggacgcgggcaacacccatcattgccgttgccaggcgggctacacgggc
agctactgcgaggaccaggtggacgagtgctcacccagcccctgccagaatggggccacc
tgcaccgactacccgggtggctactcctgtgagtgcgtggccgggtaccacggggtgaac
tgctccgaggagatcaacgagtgtgtgtcgcagccatgccagaacgggggcacctgcatc
gacctcaccaacacctacaagtgctcctgtccccggggcacacagggcgtgcactgtgag
gtcaacgtggacgactgcagcccccccatcgaccccgtctcccggggccccaagtgcttt
aacaacggcacttgcgtggaccaggtgggcggctacagctgcacctgcccacccggcttc
gtgggcgagcgctgtgagggcgacgtgaacgagtgcctgtccaacccctgtgacgcccgt
ggcacccagaactgcgtgcagcgtgtcaatgacttctactgcgagtgccgcgcgggccac
actggccgccgctgtgagtcggtcatcaacggctgcaaaggcaggccctgccagaacggg
ggcacctgcgccgtggcctccaacaccgcccgcgggttcatctgcaagtgccccgcgggc
ttcgagggcgccacgtgtgagaacgatgcacgcgcctgtgggagccggcgctgcctgaac
ggaggcacgtgcatctcgggcccgcgcagccccacctgcctgtgcctgggcgccttcacg
ggccccgagtgccagttcccggccggcagcccctgcgtgggcgggaacccctgctacaac
cagggcagctgcgagcccacggccgagagccctttctaccgctgcctgtgccccgccaag
ttcaacgggctcctgtgccacatcctggactacagcttcgggggcggcctgggcctcgac
atcccgccgccgcagatcgaggaggcgtgcgagctgcccgagtgccgcgaggaggcgggc
aacaaggtgtgcagcctggcctgcaacaaccatgcgtgcggctgggacggcggcgactgc
tcgctcaacttcaacgacccctggcagaactgctcgcagtcgctgcagtgctggaaatac
ttcagcaacggccgctgcgacagccagtgcaactctgtgggctgcctgttcgatggcttc
gactgccagcgcgcggagggccagtgcaaccccctgtacgaccagtactgcaaggaccac
ttcggcgacgggcactgcgaccagggctgcaacagcgccgagtgcgagtgggacgggctg
gactgcgcggagcacgtgcccgagcggctggcggccggcgcgctggtgctggtcgtgctg
accccgcccgcgcagctgcgcaacaactcgctgcacttcctgcgggagctcagccgcctg
ctgcacaccaacgtggtgttcaagcgcgacgcccatggccagcccatgatcttcccgtac
tacggccgcgaggaggagctgcgcaaacaccccatcaagcgcgcggcggacggctgggcg
gcgcctggggccctgctcgaccgggtggaggccgccctgctcccgcggggcctggcgggc
cgccggcgcagggagctggaccccatggacatccgcggatccatcgtctacctggagatc
gacaaccggcagtgtgtccagtcctcctcacaatgcttccagagcgccacggacgtggcc
gccttcctgggcgcacttgcctcactggggagcctcaacatcccttataagatcgaggcc
gtgcagagtgagaccgtggagccgcccccgcccccgcagctgcacttcatgtacgtggcc
gtggccgccttcgtgctgctcttcttcgtgggctgtggggtgctgctgtcccggaagcgc
cggcggcagcatggacagctctggttccccgaaggcttcaaggtctcagaggccagcaag
aagaagcggcgggagcccctcggcgaggactccgtgggcctcaagcccctgaagaatgcc
tcagatggcgctctcatggacgacaaccagaacgagtggggggacgaggacctggaggcc
aaaaagttccggttcgaggagccggtggttcttcccgacctggatgaccagacagaccac
cggcaatggacccagcagcacctggacgctgccgacctgcgtgtgtcggccatggccccc
acaccaccccagggcgaagctgacactgactgcatggacgtcaacgtccgagggccagac
ggcttcacgcccctcatgatcgcctcctgcagcggagggggcctggagacgggcaacagc
gaggaggaggaggacgcgccggccgtcatctctgacttcatctaccagggtgccagtctg
cacaaccagacagaccgcactggcgagaccgccctgcacctggccgcccgctactcgcgc
tctgacgcggccaagcgcctgctggaggccagcgcagacgccaacatccaggacaacatg
ggacgcaccccgctgcacgccgccgtgtctgccgacgcgcagggagtcttccagatcctc
atccggaaccgggccacggacctggatgcccgtatgcacgatggcacgacgccgctgatc
ctggcggcccgcctggctgtcgagggcatgctggaggacctgatcaactcgcacgccgac
gtcaatgccgtggacgacctgggcaagtctgccctgcactgggccgccgccgtgaataac
gtggaggctgccgtcgtgctcctgaagaacggggccaacaaagacatgcagaacaacaag
gaggagacacccctgttcctggctgctcgggagggcagctacgagaccgccaaggtgctg
ctggaccacttcgccaaccgggacatcacagaccacatggaccgcctgcctcgcgacatt
gctcaggagcgtatgcaccacgacatcgtgcggctgctggatgagtacagcctggtgcgc
agcccccagctgcacggccctgccctgggcggtgcgcccaccctgtccccgccgctctgc
tctcccaacggctacctgggcaacctcaagccggccgtgccgggcaagaaggcccgcaag
cccagcaccaagggcctggcctgtggcggcaaggaggccaaggacctcaaggcgcgcagg
aagaaatcccaggacggcaagggctgcctgctggacagctcgagcgtgctgtcacccgtg
gactcccttgagtcgccccacggctacctgtcggacgtggcctcgccgcccctcctgtcc
tctccgttccagcagtccccgtccgtgcccctgagccacttgcccggcatgcctgacgcc
cacctgggtgttggccacctgagcgtggctgccaagcccgagatggcagcgctgggtgca
ggcggccggctggcctttgaggcgggaccgccgcggctctcccacctgcccgtggcctcc
agcaccagcgccgtcctgggcaccgcaggtgctggcggcggaggcggggccgtgaatttc
gccgtgggcggggccgcgggcttgaacggccagtgcgagtggctgtcccggctgcagaac
ggcctggtgccaaaccagtacaacccgctgcgagggaacgtggcgtcgggccccctgagc
acgcaggcccctgccctgcagcacggaatgatgggcccgctgcatgccggcctctccacc
acggccgccctgtcgcagatgatgagctaccaggccctgcccaacacgcgcctggccggc
cagccgcacctggtgcagacccagccgctgcaacaggtgcagcaacagcagcagaacttg
cagctgcagcagcctggcctgcagacgcagcaaaacctgcagccgcccaacgtccagcag
ccgcagggcctgccgccccagccgcacctcagcgtgagctcggccgccggcggccacctg
ggccggagcttcctgggcggggagccgagccaggcggacgtgcagccgctgggccccagc
agcctggcagtgcacaccatcctgccgcaggacagccaggccctgcccaccgccctgccc
gccacgctggccccgcccatgaccacggctcagttcctgaccccgccctcgcagcacagc
tattcttcctcgccggcggacaacacccccagccaccagctgcaggtgcctgagcacccc
ttcctcaccccgtcccccgagtccccggaccagtggtccagctcgtcaccacattcccac
gtctctgactggtctgagggcatctccagcccgcccaccagcacgcagtcccacatcgcc
cacattccggaggcgctcaagtaa
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integrated database retrieval system
