Mycobacterium mantenii: MMAN_14130
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Entry
MMAN_14130 CDS
T07431
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase E1 component subunit alpha
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mman
Mycobacterium mantenii
Pathway
mman00010
Glycolysis / Gluconeogenesis
mman00020
Citrate cycle (TCA cycle)
mman00620
Pyruvate metabolism
mman00785
Lipoic acid metabolism
mman01100
Metabolic pathways
mman01110
Biosynthesis of secondary metabolites
mman01120
Microbial metabolism in diverse environments
mman01200
Carbon metabolism
mman01210
2-Oxocarboxylic acid metabolism
Module
mman_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mman00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MMAN_14130 (pdhA)
00020 Citrate cycle (TCA cycle)
MMAN_14130 (pdhA)
00620 Pyruvate metabolism
MMAN_14130 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MMAN_14130 (pdhA)
Enzymes [BR:
mman01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MMAN_14130 (pdhA)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
BBY37279
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Position
1516413..1517384
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AA seq
323 aa
AA seq
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MTDTKLAHELLSDMVRVRRMEEKCAELYSAAKIRGFLHLYVGEEAVAAGSLRALADDDAV
VATYREHAHALLRGIPMTSIMAEMFGKQEGCSRGRGGSMHLFDASKRFYGGNAIVAGGLP
LAVGIALADAMLQQKRVTACYFGDGAVAEGAFHESLNMAALWKLPVLFCCENNLYAMGTA
LDRAQSQTDLTVKAAAYQVPTLAVDGMDVEACHTAAQHGVDHVRDTGGPFFIEFRTYRFR
AHSMFDPELYRDKAEVEEWRKRDPIHAFTEKCLADGTLSKADVAEIEDAAATEIEEAVAF
AEAGTWEDVEDLERDVLTPGAAR
NT seq
972 nt
NT seq
+upstream
nt +downstream
nt
atgaccgataccaagctggcccacgaactcctgtcggatatggtccgcgtccgccgtatg
gaggaaaaatgcgcggaactgtacagcgcggccaagattcgcggcttcctgcatctgtac
gtcggtgaagaggcggtcgccgccgggtcgctgcgcgcgctggccgacgatgacgctgtg
gtcgcgacctaccgcgagcacgcgcatgcgttgctgcgcggcatcccgatgacctcgatc
atggccgagatgttcggcaaacaggaagggtgctcacggggccgcggcgggtcgatgcac
ctcttcgatgcgtccaagcggttctacggcggcaacgcgatagtcgccggcggcctgccg
ctcgcggtgggcatcgcgctcgccgacgccatgctgcagcagaagcgggtgaccgcatgc
tatttcggcgacggagcggtggccgaaggggcgtttcacgagtcgctgaacatggccgcg
ctgtggaagctaccggtgctgttctgttgcgagaacaacctttacgcgatgggcaccgcg
ttggatcgagcacagtcgcagaccgatctcaccgtcaaggcggcggcgtaccaggttccc
acactggccgtcgacgggatggatgtcgaggcgtgccataccgccgcgcaacacggggtc
gatcacgtccgcgacaccggcggcccgtttttcatcgagttccgcacctaccggttccgg
gcgcattcgatgttcgacccggaactgtatcgggacaaggcggaggtcgaagagtggcgc
aaacgcgaccccattcacgcgttcaccgagaagtgcctggccgacggcaccctgtccaag
gccgacgtagctgagatcgaggatgcggccgccaccgagatcgaggaggcagtcgcgttc
gccgaggccggaacgtgggaggacgtggaggatctcgaacgcgatgtgctgacgccgggg
gcagcgcgatga
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