KEGG   Methylobacterium mesophilicum: MMSR116_15580
Entry
MMSR116_15580     CDS       T06344                                 
Symbol
putA
Name
(GenBank) trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase
  KO
K13821  RHH-type transcriptional regulator, proline utilization regulon repressor / proline dehydrogenase / delta 1-pyrroline-5-carboxylate dehydrogenase [EC:1.5.5.2 1.2.1.88]
Organism
mmes  Methylobacterium mesophilicum
Pathway
mmes00250  Alanine, aspartate and glutamate metabolism
mmes00330  Arginine and proline metabolism
mmes01100  Metabolic pathways
mmes01110  Biosynthesis of secondary metabolites
Module
mmes_M00970  Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:mmes00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    MMSR116_15580 (putA)
   00330 Arginine and proline metabolism
    MMSR116_15580 (putA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmes03000]
    MMSR116_15580 (putA)
Enzymes [BR:mmes01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.88  L-glutamate gamma-semialdehyde dehydrogenase
     MMSR116_15580 (putA)
  1.5  Acting on the CH-NH group of donors
   1.5.5  With a quinone or similar compound as acceptor
    1.5.5.2  proline dehydrogenase
     MMSR116_15580 (putA)
Transcription factors [BR:mmes03000]
 Prokaryotic type
  Ribbon-helix-helix
   Other families
    MMSR116_15580 (putA)
SSDB
Motif
Pfam: Pro_dh Aldedh Pro_dh-DNA_bdg PRODH
Other DBs
NCBI-ProteinID: QGY03145
UniProt: A0A6B9FQB6
LinkDB
Position
3243509..3247183
AA seq 1224 aa
MRDARDSERAAGPFRAFAAALPSLSPLRAAVVEACRRPEPDCVGPLLDQARLPSDAARRV
ADQARQLVESLRRRMPRGGVEGLIHEYALSSQEGVALMCLAEALLRIPDTATRDALIRDK
IAGGDWRAHLGHSRSPFVNAATWGLLVTGRLTATRDEAGLSAALTRLIARGGEPVIRGGV
DLAMRMMGEQFVAGRTIEEALRNAARQEAKGFTYSYDMLGEAALTAHDAETYFRAYEEAI
RAIGDAAAGRGALLGPGISVKLSALHPRYSRMQRARVLAELTPRALGLARLAKERGIGFN
IDAEEADRLDLSLDVLEALATHPDLAGWDGLGFVVQAYGKRCPFVIDVLIDLARRSRHRL
MVRLVKGAYWDSEIKRAQVDGLADFPVFTRKVHTDVSYLACARRLLNAPDAVFPQFATHN
AQTLATIVEMAGPAFRLGQYEFQCLHGMGEPLYEAVVSGEILQRPCRIYAPVGTHETLLA
YLVRRLLENGANTSFVNRVADATVPVETLIADPVAAVEAAAHPGAPHPRIALPRALYGST
RANAAGLDLTDEAALSCLAEGLAVSGQIEWRAVPSGSDPASADAAVINPADRRDRVGAWR
PATPAEIERAIARAAAASAAWAATPCSDRSTTLRRAADTLEARMPVLIGLIVREAGKSYA
NAVAEIREAIDFLRYYAVEAERTRDGDHAPLGPVACIAPWNFPLAIFVGQVAAALAAGNA
VLAKPAEETPLIAAEAVRLLHAAGVPEEALQFVPGDAAVGGALVGDGRVQAVMFTGSTAV
SKGIQRVLSDRLDRHGEPVALIAETGGQNAMIVDSSALAEQVVADVIASAFDSAGQRCSA
LRILCLQEDIADRTLAMLLGALREMAIGDPRRLSTDIGPVITVAAAEAIAGHVAMMRARG
FAVHQVPLPPGTGDGSFVPPTLIEIERVADVGHEVFGPVLHVLRYARTDFDRLLGDIDAT
GYGLTFGLHSRIDETIAHVLGQVRAGNRYVNRTVIGAVVGVQPFGGSGLSGTGPKAGGPL
YLGRLSRRPSSAAVSEWAAGGAAIRPFLDWLRSNGHGRIADRLAAVHFPTFAETILEGPV
GERNLHTVRPRGRVAAIALTETGLLVQLGTILGSGNSAIVVTPENERFSLPGLPPACAAR
ITLAADLEAAPALHAVLFEGDAAGLLRLNQAVAARPGAIVPVQARTSEALNAGDLYGAAG
LIEEVSTAINTAAAGGNASLMSIG
NT seq 3675 nt   +upstreamnt  +downstreamnt
atgcgtgacgcccgtgactcagagcgtgccgccggtccgttcagggcctttgccgccgcg
ctgccgtccctgtcgcccctgcgcgcggccgtggtcgaggcctgtcggcggccggagccc
gactgcgtcggaccgctcctcgaccaagcgcgcctgccgtccgatgccgcccggcgcgtg
gccgatcaagcccgacaactcgtcgaatcgctgcggcgccggatgccccgcgggggcgtc
gagggtctgatccacgagtatgccctgtcgagccaggagggcgtggcgctgatgtgcctc
gctgaggcgctgctgcgcatccccgacaccgcgacgcgcgacgcgctgatccgcgacaag
atcgcgggcggcgactggcgcgcccatctcgggcacagccggtcgcccttcgtgaacgct
gcgacttggggattgctcgtcaccggccgtctcacagcgacccgggacgaggccggcctg
tccgcggcgctcacgcggctgatcgcccgcggcggcgagccggtgatccgtggcggcgtc
gatctcgccatgcggatgatgggtgagcaattcgtcgccggccggaccatcgaggaggct
ctccgcaacgccgcgcggcaggaggcgaagggtttcacctactcgtacgacatgctcggc
gaggccgcgttgaccgcgcacgacgccgaaacctacttccgcgcctacgaagaggccatc
cgggcgatcggggatgccgcggccggtcgcggcgcgcttctcggacccggaatttcggtc
aagctgtcggcgctgcatccccgctactcgcggatgcagcgcgcacgcgtcctggcggag
ctgacgccgcgggcgcttgggctcgcgcgcctggcgaaggagcgtggcatcggcttcaac
atcgacgcggaagaggccgaccgcctcgatctgtcgctggacgtcctggaagccctcgcg
acccatccggacctcgccggctgggacggcctcggcttcgtcgtgcaggcctacggcaag
cgctgtcccttcgtgatcgacgtgctgatcgacctcgcccggcgcagccggcaccggctg
atggtgcgtctcgtgaagggcgcctactgggacagcgagatcaaacgggctcaggtcgac
gggctcgcggatttcccggtcttcacccggaaagttcacacggacgtctcgtacctcgcc
tgcgcgcgccgcctcctgaacgcgccggacgccgtcttcccgcaattcgcgacccacaac
gcgcagacactcgccacaatcgtggagatggcgggcccggcattccggctcggccagtac
gagttccagtgcctgcacggcatgggcgagcccctctacgaggcggtggtgtccggggag
atcctgcagaggccctgccggatctacgcgcccgtgggcacgcacgagaccttgctggcc
tatctggtccggcgcctgctggagaacggggccaatacctccttcgtcaaccgggtcgcc
gacgccaccgtgccggtggagacgctcatcgccgatccggtcgccgcggtagaggctgcg
gcacatccgggcgcgccgcacccgcgcatcgcgttgccgcgggctctctacggttcgacc
cgtgccaacgcggccggcctcgacctcaccgacgaggcggcgctcagctgtctcgccgaa
ggacttgctgtgagcgggcaaatcgagtggcgcgccgtaccgtctggcagcgatcccgct
tcggccgacgcggccgtcatcaatccggcggatcgacgggaccgggtgggcgcgtggcgg
ccggccacgccggccgagatcgagcgagcgatcgcacgcgccgctgccgcctctgcagcc
tgggctgcgaccccctgcagcgatcggtccaccacgctgcgtcgcgcggccgacaccctc
gaggcgagaatgccggtcttgatcggcctgatcgtgcgcgaagccgggaagtcctacgcc
aacgccgtggcggagatccgtgaggccatcgacttcctgcgctactatgccgtcgaggcc
gagcggacgcgcgatggcgaccacgcaccgctcggtccggtcgcctgcatcgcgccctgg
aatttcccgctggcgatcttcgtcggccaggtggctgcggcgctcgcggcgggcaacgcg
gtcctcgccaagcccgccgaggagacccccctgatcgccgccgaggccgtccgcttgctg
catgccgcaggcgtccctgaggaagcgctccagttcgtgcccggtgacgccgcggtcggg
ggcgctctggtcggcgacgggcgggtgcaggccgtgatgttcacgggctcgacggcggtc
tcgaaaggcatccagcgcgtgctctccgaccgcctcgatcgtcacggcgagcccgtcgcg
ctcatcgccgagaccggcggccagaacgccatgatcgtcgattcttcggccctggccgag
caggtcgtggcggatgtcatcgcctcggccttcgattccgcgggtcagcgctgttcggcc
ctgcgcatcctgtgcctgcaggaggacatcgccgaccggacgctcgcgatgctgctgggg
gcgcttcgcgagatggcgatcggggatccccgccgcctctccacggatatcggcccagtc
atcaccgtcgcggccgccgaggccattgccggccacgtggcgatgatgcgcgcccgcggc
ttcgccgtgcaccaggtcccccttccgccgggcacgggagacgggagtttcgtgccgccg
acgctgatcgagatcgagcgcgtcgccgacgtcgggcacgaggtgttcggaccggtcctg
cacgtcctgcgctacgcccggaccgacttcgaccggctgctcggggacatcgatgccacc
ggctacggccttaccttcgggctgcacagccgcatcgacgagacgatcgcgcatgttctc
ggacaggtgcgcgctggcaaccgttacgtgaaccggaccgtgatcggcgcggtggtgggg
gtgcagcctttcggcggttcaggcctgtccggcaccgggccgaaggccggcggccccctc
tatctcggccggctctcccggcggccgtcgagcgccgccgttagcgagtgggcagccggt
ggtgcggcgatccgcccgttcctggactggctgcgctcgaacggccacggccggatcgcc
gaccgtctcgcggccgtccacttccccaccttcgcggaaacgatcctggaagggcccgtc
ggcgagcgcaaccttcacacggtccgtccccgaggccgcgtcgccgcaatcgccctgacc
gagacgggactcctcgtgcaactcgggacgattctaggcagcgggaacagcgcgatcgtc
gtcaccccggagaacgagcgattcagcctccctgggcttccgcccgcgtgcgccgcacgg
attactttggccgcagatctcgaggccgcaccggcgctccacgcggtcctgttcgaaggt
gatgcggccggcctgcttcgcctgaaccaggccgtcgcggcgcgccccggggcgatcgtg
cctgtccaggcgcgcacgtcggaggcgctgaacgcaggcgacctctacggtgcggccggc
ctcattgaggaggtctcgaccgcgatcaacaccgccgcggccggggggaatgccagcctc
atgagcatcggctag

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