Mycobacterium marinum M: MMAR_3489
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Entry
MMAR_3489 CDS
T00694
Name
(GenBank) pyruvate dehydrogenase E1 component (alpha subunit)
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mmi
Mycobacterium marinum M
Pathway
mmi00010
Glycolysis / Gluconeogenesis
mmi00020
Citrate cycle (TCA cycle)
mmi00620
Pyruvate metabolism
mmi00785
Lipoic acid metabolism
mmi01100
Metabolic pathways
mmi01110
Biosynthesis of secondary metabolites
mmi01120
Microbial metabolism in diverse environments
mmi01200
Carbon metabolism
mmi01210
2-Oxocarboxylic acid metabolism
Module
mmi_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmi00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
MMAR_3489
00020 Citrate cycle (TCA cycle)
MMAR_3489
00620 Pyruvate metabolism
MMAR_3489
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
MMAR_3489
Enzymes [BR:
mmi01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
MMAR_3489
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
Transketolase_N
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
ACC41908
UniProt:
B2HJW6
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All DBs
Position
4295731..4296735
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AA seq
334 aa
AA seq
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MDAKLARELLSDMVRVRRMEEKCAELYSAAKIRGFLHLYVGEEAVAAGSLRVLAEDDAVV
ATYREHAHALLRGIPMTSIMAEMFGKQEGCSRGRGGSMHLFDQARRFYGGNAIVAGGLPL
AVGISLADSMLKRNRVTACYFGDGAVAEGAFHESLNMAALWKLPVLFLCENNLYAMGTAL
HRAQSQTDLTVKAASYNVATLAVDGMDVAACMSATQQGVDHIRSTGGPFFIEFRTYRFRA
HSMFDPELYRDKAEVQRWRERDPIRLFTEQCLNSGTLTDDDVRDIEGSAADEIAAAVAFA
DAGTWEDASDLERDVLTPPDSCDATAESTWEPAR
NT seq
1005 nt
NT seq
+upstream
nt +downstream
nt
atggatgcgaagctggcgcgcgagctgctgtcggacatggtgcgggtgcgccggatggaa
gagaagtgcgcggaactctacagcgcagccaagatccgcggatttctgcatctctacgtc
ggagaggaggcggtagccgccggatctctgcgagtgcttgccgaggacgacgcggtggtg
gcgacatatcgcgagcacgcgcacgcgctgctgcgcggtattccgatgacctcgatcatg
gccgagatgttcggcaagcaggagggctgctcgcgaggtcgcggcgggtcgatgcatctg
ttcgaccaggcccggcgattctacggcggcaacgccattgtcgccggaggcctgccactg
gcggtcggcatctcgctcgccgactccatgctgaagcgaaatcgggtcacggcatgctac
ttcggtgatggagccgtcgccgaaggcgcgtttcacgagtcactgaacatggcggcactg
tggaagttgccggtgctgttcctatgcgagaacaacctgtacgccatgggcaccgcattg
catcgagcccagtcgcagaccgacctcacggtcaaggcggcgtcgtacaacgttgccacg
ctggcggtcgacgggatggacgtagcggcctgcatgagcgctacccagcagggtgtcgac
cacatccgcagcaccggcggaccgttcttcatcgagttccgtacctaccgattccgggcc
cattcgatgttcgaccccgagctgtaccgggacaaggcggaagtgcagcgatggcgcgag
cgcgacccgatccggctgttcaccgaacagtgtctgaacagcggcacgctgaccgatgac
gacgtgcgcgacatcgaagggtcggcggccgacgagatcgctgcggcggttgccttcgcc
gatgccggaacatgggaggacgcatcggatctcgaacgcgacgtgctgactccgcccgat
agctgcgatgcgaccgcggaatcgacctgggagccggcgcgatga
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