Marmota marmota marmota (Alpine marmot): 107144140
Help
Entry
107144140 CDS
T09644
Symbol
Pdha1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00010
Glycolysis / Gluconeogenesis
mmma00020
Citrate cycle (TCA cycle)
mmma00620
Pyruvate metabolism
mmma00785
Lipoic acid metabolism
mmma01100
Metabolic pathways
mmma01200
Carbon metabolism
mmma01210
2-Oxocarboxylic acid metabolism
mmma04066
HIF-1 signaling pathway
mmma04922
Glucagon signaling pathway
mmma05230
Central carbon metabolism in cancer
mmma05415
Diabetic cardiomyopathy
Module
mmma_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
107144140 (Pdha1)
00020 Citrate cycle (TCA cycle)
107144140 (Pdha1)
00620 Pyruvate metabolism
107144140 (Pdha1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
107144140 (Pdha1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
107144140 (Pdha1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
107144140 (Pdha1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
107144140 (Pdha1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
107144140 (Pdha1)
Enzymes [BR:
mmma01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
107144140 (Pdha1)
BRITE hierarchy
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
107144140
NCBI-ProteinID:
XP_048652331
LinkDB
All DBs
Position
Unknown
AA seq
398 aa
AA seq
DB search
MYAGLHASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRR
MELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVRE
ILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTL
YGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLR
VDGMDILCVREATRFAAAYCRSGKLCSSHSNISVDVSLPLRNVLRLHLAICPTGTVLTPI
TVFLSSYSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQF
ATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1197 nt
NT seq
+upstream
nt +downstream
nt
atgtatgctggtttacatgcaagcagagtgctagtggcatcccgtaattttgcaaatgat
gctacatttgaaattaagaaatgtgaccttcaccggctggaagagggccctcctgtcacg
acagtgctcaccagggaggatgggctcaaatactataggatgatgcagactgtgcgccga
atggagttaaaggctgatcagctttataaacagaaaatcattcgtggtttctgtcacttg
tgtgatggtcaggaagcctgctgtgtgggcctggaggctggcataaatcccacggaccac
ctcatcacagcctaccgggctcatggtttcacctttactcgaggcctttctgtccgagaa
attcttgcagagctaacaggacgaagaggaggctgtgctaaagggaaaggaggatcgatg
cacatgtatgccaagaacttctatgggggcaatggcattgtcggagctcaggtgcccctg
ggagctgggattgctctggcctgcaagtacaatggaaaagatgaggtctgtttgacttta
tatggtgatggtgctgctaaccagggtcagatatttgaagcttacaatatggcagcattg
tggaaattaccttgtattttcatctgtgagaataaccgctatggaatgggaacatctgtt
gagagagcagcagccagcactgattactacaaaagaggcgattttattcctgggcttagg
gtggatggaatggatatactgtgtgtccgagaggcaacaaggtttgcggctgcctattgt
agatctgggaagctctgctcttctcacagtaacattagtgttgatgtgtcccttcctctc
aggaatgtactcagacttcacctagctatctgccccactggaactgttcttacacctatc
actgtgtttctttcctcatacagttaccgcacacgagaagaaattcaggaagtaagaagt
aagagtgaccctataatgcttcttaaggatagaatggtgaacagcaatcttgccagtgtt
gaagaattaaaggaaattgatgttgaagtaaggaaagaaattgaggacgctgcccagttt
gccacagctgatcctgagccacctttggaggaactaggctaccacatctacagcagcgat
ccaccctttgaagtgcgtggtgccaaccagtggatcaagtttaagtcagtcagttaa
DBGET
integrated database retrieval system
