KEGG T09644: 107147446

Marmota marmota marmota (Alpine marmot): 107147446

Entry

107147446         CDS       T09644

Symbol

Hsd17b7

Name

(RefSeq) 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 isoform X1

K13373

17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]

Organism

mmma Marmota marmota marmota (Alpine marmot)

Pathway

mmma00100

Steroid biosynthesis

mmma00140

Steroid hormone biosynthesis

mmma01100

Metabolic pathways

mmma04913

Ovarian steroidogenesis

Module

mmma_M00101

Cholesterol biosynthesis, FPP => cholesterol

Brite

KEGG Orthology (KO) [BR:mmma00001]
09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    107147446 (Hsd17b7)
   00140 Steroid hormone biosynthesis
    107147446 (Hsd17b7)
09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    107147446 (Hsd17b7)
Enzymes [BR:mmma01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     107147446 (Hsd17b7)
    1.1.1.270  3beta-hydroxysteroid 3-dehydrogenase
     107147446 (Hsd17b7)

Motif

Pfam:

adh_short adh_short_C2 KR Epimerase SwrA Polysacc_synt_2 NAD_binding_10 Eno-Rase_NADH_b

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

Ensembl:

UniProt:

LinkDB

Position

Unknown

AA seq 335 aa
MRKVVLVTGASSGIGLALCKRLLAEDNELYLCLACRNTGKAEAVRATLLACYPTAEVTTV
QVDVSNLQSVFEACKELKQRFQRLDYVYLNAGIMPNPQLNIKAFFSGLFSRKAIHMFSTA
EGLLTQQDRVTADGLQEVFATNIFGHFILIRELEPLLCHSYNPSQLIWTSSRNARKSNFS
LEDIQHRKGQEPYSSSKYATDLLNVALNRHFNQQGLYSSVICPGTVLTNLTYGILPPFLW
TLLMPVIWLLRFFANSFTLTPYNGTEALIWLFHQKPESLNPLIKYLSATTGFGSNYVTVE
KMDIDEDTAERFYQNLLELEKRVRVNTTQKSDHQS

NT seq 1008 nt +upstreamnt +downstreamnt
atgcgaaaggtggttttggtcaccggggcgagcagtggcatcggcctagccctttgcaag
aggcttctggcagaagacaatgagctttacctttgtttggcgtgcaggaacacgggcaag
gcagaagctgtccgtgctactctgttggcctgttaccccactgctgaagtcaccactgtg
caggtggatgtcagcaacttacagtcagtgttcgaggcttgcaaagaacttaagcaaagg
tttcaaagattagactatgtgtatctaaatgctgggatcatgcctaacccacagctaaat
attaaagcatttttctctggcctcttttcaagaaaagcgattcatatgttctccacagct
gaaggactgctgacccaacaggatagggtcactgctgatgggcttcaggaggtgtttgca
accaatatctttggacactttatcctgattcgggaactagaacctctcctctgtcacagt
tataatccatctcaactcatctggacatcatctcggaatgcaaggaaatctaatttcagt
cttgaagacatccagcacaggaaaggccaggaaccctacagctcttccaaatacgccact
gaccttctaaatgtggctttgaataggcacttcaaccagcagggtctgtattcgagtgta
atttgcccagggacagtactgaccaatttgacctatggaattctacctccatttttatgg
acactgctgatgccagtgatttggctgcttcgcttttttgcaaattcttttactttgaca
ccatataatggaacagaagcattgatttggcttttccatcaaaagccagagtctctcaat
cctctgatcaaatatctgagtgctactacaggctttggaagtaattatgtcacagtggaa
aagatggacatagatgaagacactgctgaaaggttttaccaaaacttattggaactggaa
aagcgtgttagggtcaacaccactcaaaaatcagatcaccagagctga

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