Marmota marmota marmota (Alpine marmot): 107148970
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Entry
107148970 CDS
T09644
Symbol
Ezh2
Name
(RefSeq) histone-lysine N-methyltransferase EZH2 isoform X2
KO
K11430
[histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:
2.1.1.356
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00310
Lysine degradation
mmma01100
Metabolic pathways
mmma03083
Polycomb repressive complex
mmma05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
107148970 (Ezh2)
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
107148970 (Ezh2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
107148970 (Ezh2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmma03036
]
107148970 (Ezh2)
Enzymes [BR:
mmma01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase
107148970 (Ezh2)
Chromosome and associated proteins [BR:
mmma03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
107148970 (Ezh2)
Polycomb repressive complex (PRC) and associated proteins
PRC2.1
107148970 (Ezh2)
PRC2.2
107148970 (Ezh2)
BRITE hierarchy
Motif
Pfam:
Ezh2_MCSS
PRC2_HTH_1
SET
EZH2_WD-Binding
preSET_CXC
Motif
Other DBs
NCBI-GeneID:
107148970
NCBI-ProteinID:
XP_015349213
Ensembl:
ENSMMMG00000007126
LinkDB
All DBs
Position
Unknown
AA seq
757 aa
AA seq
DB search
MGHTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILERTEILNQEW
KQRRIQPVHIMTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYSWSPLQQNF
MVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALGQ
YNDDDDDDDGDDPDEREEKQKDVEDSRDGIPQTCVQYVRNKESRPPRKFPSDKIFEAISS
MFPDKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRC
FKYDCFLHPFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKR
PGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSSSE
ANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEF
RVKESSIIAPVPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQP
CDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCG
AADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQD
EADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIG
IFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgggccacactgggaagaaatctgagaagggaccagtttgttggcggaagcgtgtaaaa
tcagagtacatgcgactgagacagctcaagaggttcagacgagctgatgaagtaaagagt
atgtttagttccaatcgtcagaaaattttggaaagaacggaaatcttaaaccaagaatgg
aaacagcgaaggatacagcctgtgcacatcatgacttctgtgagctcattgcgcgggact
agggagtgttccgtgaccagtgacttggattttccgacacaagtcatcccattaaagaca
ctgaatgccgttgcttcagtacccataatgtattcttggtctcccttacagcagaatttt
atggtggaagatgaaactgttttacataacattccttatatgggggatgaagttctagac
caagatggcactttcattgaagaactaattaaaaattatgatggaaaagtacatggagat
agagaatgtgggtttataaatgatgaaatttttgtggagttggtgaatgctcttggtcaa
tacaatgatgatgatgatgatgatgatggagatgatcctgatgaaagagaagaaaaacag
aaagatgtagaggatagccgagatggtattccacagacatgtgtacaatatgttagaaat
aaagaaagccgtccacctcggaaatttccttctgataaaatttttgaagccatttcctca
atgtttccagataagggcacagcagaagaactaaaggaaaaatataaagaacttactgag
cagcagctcccaggtgcacttcctcctgaatgtactcccaacatagatggaccaaatgct
aaatctgttcagagagagcaaagcttgcattcatttcatacgcttttctgtcggcgatgt
tttaagtatgactgcttcctacatccttttcatgcaacacccaacacatacaagcggaaa
aacacagaaacagctctggacaacaagccttgtggaccccagtgttaccagcatttggag
ggagcaaaggagttcgctgctgctctcactgctgagcggataaagaccccaccaaaacgc
ccaggaggccgcagaagggggcggcttcccaacaacagcagcaggcccagcacccccacc
atcaatgtgctggagtcaaaggacacagacagtgacagggaagcagggactgaaactggg
ggagagaacaatgataaagaagaggaggagaaaaaagatgaaacttccagctcctctgaa
gcaaattctcggtgtcaaacaccaataaagatgaagccaaatatcgaacctcctgagaat
gtggagtggagtggtgctgaagcctcgatgttcagagtcctcattggtacttactatgat
aacttctgtgccattgctaggttaattgggaccaaaacatgtagacaggtgtatgagttt
agagtcaaagaatccagcatcattgctccagttcctgcggaggatgttgacactccccca
agaaagaagaaaaggaaacatcggttgtgggctgcgcactgcagaaagatacaactgaaa
aaggacggctcctctaaccatgtttacaactatcaaccctgtgaccatccacggcagcct
tgtgacagttcatgcccttgtgtgatagcacaaaatttttgtgagaagttttgtcaatgt
agttcagagtgtcaaaaccgctttcctgggtgccgttgcaaagcacagtgcaacaccaag
cagtgcccatgctatctggctgtccgagagtgtgatcctgacctctgtcttacatgcgga
gctgctgaccactgggacagtaaaaatgtgtcctgcaagaactgcagtattcagcggggc
tccaaaaagcatttattgctggcaccatctgatgtggcaggctgggggatttttatcaaa
gatcctgtacagaaaaatgaattcatctcagaatactgtggagagattatttctcaagat
gaagcagacagaagagggaaggtgtatgataagtacatgtgcagctttctattcaacttg
aacaatgattttgtggtggatgcaacccgcaagggtaacaaaattcgttttgcaaatcat
tcagtaaatcctaactgctatgcaaaagttatgatggttaatggcgatcacaggataggc
atctttgctaagagagccatccagactggtgaagagctgttttttgactacagatacagc
caggccgatgccctgaagtatgtgggcattgaaagagaaatggaaatcccttga
DBGET
integrated database retrieval system
