KEGG   Marmota marmota marmota (Alpine marmot): 107156899
Entry
107156899         CDS       T09644                                 
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase
  KO
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Organism
mmma  Marmota marmota marmota (Alpine marmot)
Pathway
mmma00350  Tyrosine metabolism
mmma00790  Folate biosynthesis
mmma01100  Metabolic pathways
mmma04728  Dopaminergic synapse
mmma04917  Prolactin signaling pathway
mmma05012  Parkinson disease
mmma05030  Cocaine addiction
mmma05031  Amphetamine addiction
mmma05034  Alcoholism
Module
mmma_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:mmma00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    107156899 (Th)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    107156899 (Th)
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    107156899 (Th)
  09156 Nervous system
   04728 Dopaminergic synapse
    107156899 (Th)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    107156899 (Th)
  09165 Substance dependence
   05030 Cocaine addiction
    107156899 (Th)
   05031 Amphetamine addiction
    107156899 (Th)
   05034 Alcoholism
    107156899 (Th)
Enzymes [BR:mmma01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2  tyrosine 3-monooxygenase
     107156899 (Th)
Motif
Pfam: Biopterin_H TH_ACT TOH_N LTP_2
Other DBs
NCBI-GeneID: 107156899
NCBI-ProteinID: XP_048663577
LinkDB
Position
Unknown
AA seq 419 aa
MPTPSATTPQPKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAAAAAAAAA
AAASSEPGDPLEAVAFEEKDGKALLSLLFSLKGTKPCSLSRAVKVFETFEAKIHHLETRP
AQRPRAESPHLEYFVRFEVPSGDLAALLSSVRRVSDDVRSAGEDKVPWFPRKVSQLDKCH
HLVTKFDPDLDLDHPGFSDQGYRQRRKLIAEIAFQYKHGEPIPRVEYTAEEIATWKEVYS
TLRGLYATHACREHLEAFRLLERFSGYCEDSIPQLEDVSRFLKERTGFKLRPVAGLLSAR
DFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQVCVGLSQG
QAHSAPPGYASRIQRPFSVKFDPYTMAIDVLDSPHTIRRSLEGVQDELHTLTHALSAIS
NT seq 1260 nt   +upstreamnt  +downstreamnt
atgcccacacccagcgccaccacgccgcagcccaagggcttccgaagggccgtctcggag
ctggacgccaagcaggcagaggctatcatgtccccacgtttcatcgggcggcggcagagc
ctcatcgaggatgcccgcaaggagcgggaggcggcggcagcggcggcagcggcggcggct
gcagcagcctcctcggagcccggagaccccctggaggccgtggcgttcgaggagaaggat
gggaaggccctgctgagcctgctcttctccctgaagggcaccaagccctgctcgctgtcc
cgggctgtgaaggtgtttgagacatttgaagccaagatccatcacctggagacccggcca
gcccagaggccacgggcagagagccctcacctggagtactttgtgcgctttgaagtgccc
agcggggacctggcggccctgctcagctccgtgcgccgggtgtcagacgatgtgcgcagt
gccggggaggacaaggtcccatggttccccaggaaggtgtcgcagctggacaagtgtcac
cacctggtcaccaagtttgatcctgacttggacttggaccatccgggcttctcggaccag
gggtaccgccagcgccggaagctgattgccgagatcgccttccagtacaagcatggtgaa
cccattccccgcgtggagtacacagccgaggagattgccacctggaaggaggtctacagc
accctgaggggcctctacgccacccacgcctgccgcgagcacctggaagccttccggctg
ctggagcgcttcagcggctactgcgaggacagcattccccagctggaggacgtttcccgc
ttcctgaaggagcggacgggcttcaagctgcggcctgtggctggccttctgtcggccagg
gacttcctggccagcctggccttccgtgtgttccagtgcacccagtacatccgccacgcc
tcctcacccatgcactcgccagagccggactgctgtcacgagctgctggggcacgtgccc
atgctggctgaccgcacgttcgcacagttctcccaggtgtgtgtgggcctcagccagggc
caggcacattccgccccaccgggctatgcctctcgaatccagcgccccttctctgtgaag
tttgacccatacacgatggccatcgatgtgctggacagtccccacaccatccgtcgctct
ctggagggtgtccaggatgagctgcacaccctgacccatgcattgagtgccatcagctag

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