Marmota marmota marmota (Alpine marmot): 107159127
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Entry
107159127 CDS
T09644
Symbol
Notch1
Name
(RefSeq) neurogenic locus notch homolog protein 1
KO
K02599
Notch 1
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma01522
Endocrine resistance
mmma04330
Notch signaling pathway
mmma04658
Th1 and Th2 cell differentiation
mmma04919
Thyroid hormone signaling pathway
mmma05020
Prion disease
mmma05165
Human papillomavirus infection
mmma05200
Pathways in cancer
mmma05206
MicroRNAs in cancer
mmma05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
107159127 (Notch1)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
107159127 (Notch1)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
107159127 (Notch1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107159127 (Notch1)
05206 MicroRNAs in cancer
107159127 (Notch1)
09162 Cancer: specific types
05224 Breast cancer
107159127 (Notch1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
107159127 (Notch1)
09164 Neurodegenerative disease
05020 Prion disease
107159127 (Notch1)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
107159127 (Notch1)
BRITE hierarchy
Motif
Pfam:
EGF
hEGF
EGF_CA
EGF_2
Ank_2
Ank
Notch
NOD
NODP
Ank_4
Ank_5
Ank_3
EGF_3
DL-JAG_EGF-like
JAG1-like_EGF2
Motif
Other DBs
NCBI-GeneID:
107159127
NCBI-ProteinID:
XP_015361152
Ensembl:
ENSMMMG00000009940
LinkDB
All DBs
Position
Unknown
AA seq
2548 aa
AA seq
DB search
KGWACPQKPTDLSPASPPGLRCSQPGGACLNGGRCQVVNSTEETCVCSGAFVGQRCQDPN
PCLSSPCKNAGTCRVVDRGGAADYACICPLGFSGPLCLTPLDNACLSSPCRNGGTCDLVT
LTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFESSYICGCPPGFHGPTCRQDVNE
CSQSPGLCRHGGTCHNEVGSYRCVCRATHTGPHCELPYVPCSPSPCQNGGTCRPTGDTTY
ECACLPGFTGQNCEENVDDCPGNGCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQL
MPTACQNGGTCHNTLGGYNCVCVNGWTGEDCGENIDDCASAACFHGATCHDRVASFYCEC
PHGRTGLLCHLSDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECALGAN
PCEHAGKCLNTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPG
YEGVYCEVNMDECASSPCLHGGRCLDKINEFVCECPTGFSGHLCQYDVDECASTPCRNGA
RCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCQPGYTGHHCE
TNINECHSQPCRHGGTCQDRDNAYFCFCLKGTTGPNCEVNLDDCASSPCDSGTCLDKIDG
YECACEPGYTGSMCNVNIDECAANPCHNGGTCEDGINGFTCHCPEGYHDPTCLSEVNECN
SSPCVHGVCRDSLNGYKCDCEPGWSGTNCDINTNECESNPCVNGGTCKDMTSGYVCTCRE
GFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEGVLAPCAPSPCRNS
GVCKESEDYESFFCVCPVGWQGQTCEIDVNECVKSPCRNGASCQNTNGSYRCLCQAGYTG
RNCESDIDDCRPNPCHNGGSCTDGVNTAFCDCLPGFQGAFCEEDINECASNPCHHGANCT
DCVDSYTCTCPAGFNGIHCENNTPDCTESSCFNGGTCVDGINAFTCLCPPGFTGSYCQHD
INECDSRPCLHGGTCQDSYGTYKCTCPQGYTGLNCQDLVRWCDSSPCKNGGKCWQTNTLY
RCECRSGWTGLYCDVPSVSCEVAAQQRGVKVSHLCQHGGLCVDAGNTHHCRCQAGYTGSY
CEDEVDECSPSPCQNGATCTDYLGGYSCKCMAGYHGANCSEEINECLSDPCQNGGTCIDL
TNTYKCSCPRGTQGVHCEINVDDCSPPLDPASRSPRCFNNGTCVDQVGGYSCTCPPGFVG
ERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRPGHTGRRCESVINGCKGKPCKNGGT
CNVASNTARGFICKCPAGFEGATCENDARTCGTLRCLHGGTCISGPRSPTCLCLAPFTGP
ECQFPASSPCLSGNPCYNQGSCEPTSESPFYRCLCPPKFNGLLCHILDYSFGGGAGRDIP
PPQIEEACELPECQADAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFS
DGRCDSQCNSAGCLFDGFDCQHAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDC
AEHVPERLAAGTLVLVVLLPPQQLRNHSLHFLRELSRVLHTNVVFKRDAQGHQMIFPYYG
HEEELRKHPIKRAAGWAAPGSLLGQATASLLPGSSRRQRRELDPMDIRGSIVYLEIDNRQ
CLQSSSQCFQSATDVAAFLGALASLGSLNIPYKIDAVQSETVEPPPPAQLHLMYVAAAAF
VLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASDGA
LMDESQNEWGDEGLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMSAMAPTPPQ
GEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQT
DRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNR
ATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAA
IVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQER
MHHDIVRLLDEHNLVRSPQLHGAALGSTPRLSPTLCSPSGYLGNLKPSVQGKKARKPSTK
GPACGSKEARDLKARRKKSQDSKGCLLDSSSMLSPVDSLESPHGYLSDVASPPLLPSPFQ
QSPSMPLNHLPGMPDAHLGISHLNVAAKPEMAALGGGSRLAFEPGPPRLSHLPVASSTGT
ILGASSTGAVNFTVGGAAGLNGQCEWLSRLQSGMVPSQYNPLRGAVAPGTLSTQAPALQH
TMMGSLPGSLSASALSQMMSYQGLPSARHATQPHLVQPQQGPQQNLQMQQQNLQMPDMQQ
PQSLQPPAQPHLGVGTAASGHLGRSLLGGEPSQDVQPLGPSNLTVHTILPQESQALPTSL
PSSLVPPMTTTQFLTPPSQHSYSSSPVDNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHS
NISDWSEGISSPPTTMQSQVTHIPEAFK
NT seq
7647 nt
NT seq
+upstream
nt +downstream
nt
aaggggtgggcctgcccccagaagcccactgacctctcccctgcctctcccccaggtctg
aggtgctcccagccagggggagcctgcctgaacggcggcaggtgccaagtggtcaacagc
accgaggagacctgtgtgtgcagtggggccttcgtgggccagagatgccaggatcctaac
ccgtgcctcagctctccctgcaagaacgccgggacgtgccgtgtggtggaccgcggtggg
gctgcagactatgcctgtatctgccccctgggcttctctgggcccctctgcctgacgccc
ctcgacaacgcctgcctgtccagcccctgccggaacgggggcacctgcgacctggtcacg
ctcacagagtacaagtgccgctgccccccaggctggtcagggaaatcatgccaacaggct
gatccatgtgcttccaacccctgtgccaatggcggccagtgtctgcccttcgagtcctcg
tacatctgcggctgcccaccgggcttccacggcccgacctgcaggcaagacgtcaatgag
tgcagccagagcccggggctgtgccgccatgggggcacctgccacaacgaggttggctcc
taccgctgcgtctgccgcgccacccacactggtccccactgcgagctgccctatgtgccc
tgcagcccctcaccctgccagaatgggggcacctgccgccccacgggggacaccacctac
gagtgtgcctgccttccaggcttcacgggtcagaactgcgaggagaacgtggatgactgt
ccaggaaacggctgcaagaacgggggtgcctgcgtggacggtgtgaacacctacaactgc
cgctgtccaccagagtggacaggccagtactgcacagaggacgtggacgagtgccagctc
atgcccaccgcctgccagaatggtggcacctgccacaacaccctcggcggctacaactgt
gtgtgcgtcaatggctggacgggcgaggactgtggcgagaatattgacgactgtgccagt
gctgcctgcttccacggtgccacctgccacgaccgcgtggcctccttctactgcgagtgt
ccccacggccgcactggcctgctctgccaccttagcgacgcatgcatcagcaacccttgc
aatgagggctccaactgtgacaccaaccctgtcaatggcaaggccatctgcacctgtccc
tcgggatacacggggccagcctgcagccaggacgtggacgaatgtgcactgggcgccaac
ccctgtgagcacgcgggcaagtgcctcaacacgctgggctccttcgagtgccagtgtctg
cagggctacacgggcccccgctgcgagatcgatgtcaacgagtgcgtctcgaacccctgt
cagaacgatgccacctgcctggaccagatcggggagttccagtgcatctgtatgcccggc
tatgaaggcgtgtactgtgaggtcaacatggatgagtgtgccagcagcccgtgcctccat
ggtggccgctgcctggacaagatcaacgagttcgtatgcgagtgccccacaggcttcagc
gggcacctgtgccagtatgacgtggacgagtgtgccagcacaccctgcaggaacggggcc
aggtgcctggatgggcccaacacctacacctgtgtgtgcacggaaggctacacagggacc
cactgcgaggtggacatagatgagtgtgaccctgacccctgtcactacggctcctgcaaa
gatggtgtggccaccttcacctgcttgtgccagccgggctacacgggccaccactgcgag
accaacattaacgagtgccacagccaaccctgtcgccatggtggcacctgtcaggaccgc
gacaatgcctacttctgcttctgccttaaggggaccacaggacccaactgtgaggtcaat
ctggacgactgtgccagcagcccctgtgactcgggcacctgcttagataagatcgatggc
tacgagtgtgcttgtgagccaggctacacagggagtatgtgcaacgtcaacatcgacgag
tgtgcggcgaacccctgccacaacgggggcacctgtgaggacggcatcaacggcttcacc
tgccactgccccgagggctaccacgaccccacctgtctgtccgaggtcaacgagtgtaac
agcagcccctgcgtccatggggtctgccgggacagcctcaatgggtacaagtgtgactgt
gagcctgggtggagtgggacaaactgtgatatcaacaccaacgagtgcgagtccaacccc
tgtgtcaatggcggcacctgcaaagacatgaccagcggctatgtgtgcacgtgccgggaa
ggcttcagtggccccaactgccagaccaacatcaacgagtgtgcgtccaacccatgcctg
aaccagggcacctgcatcgatgacgtcgctgggtacaagtgcaactgcctactgccctac
acaggagccacatgtgagggggtgctggccccgtgtgcccccagcccctgcagaaacagc
ggggtgtgcaaggagtcggaggactacgagagctttttctgcgtctgcccagtgggctgg
caggggcagacctgtgagattgatgtcaatgagtgcgtgaagagcccctgccgcaatggc
gcgtcctgccagaacaccaacggtagctaccgctgcctctgccaggcaggctacacaggg
cgcaactgtgagagtgacatcgatgactgccggccgaacccttgtcacaatggtggctcc
tgcacagacggcgtcaacacggccttctgcgactgcctgcctggcttccagggtgccttt
tgtgaggaggacatcaacgagtgcgccagcaacccctgccaccacggggccaactgcacg
gactgcgtggacagctacacctgcacctgccccgcgggcttcaatggcatccactgtgag
aacaacacgcccgactgcacagagagctcctgcttcaacggcggcacttgtgtggacggc
atcaatgccttcacctgcctgtgccctcccggcttcacgggcagctactgtcagcatgac
attaacgagtgtgattcacggccctgcctgcacggtggcacctgccaggacagctacggc
acctacaagtgcacctgcccgcagggctacactggcctcaactgccaggacctcgtgcgc
tggtgtgattcctctccctgcaagaatggaggcaagtgctggcagaccaataccctgtat
cgctgtgagtgccgcagtggctggactggcctctactgtgacgtgcccagtgtctcctgt
gaggtggccgcacagcagcgaggggtcaaggtctcccacctgtgccagcacggaggactg
tgtgtggatgcaggcaacacccaccactgccgctgccaggcggggtacaccggcagctac
tgtgaggacgaggtggacgagtgctcgcccagcccctgccagaacggggccacctgcacc
gactacctgggcggttactcctgcaagtgcatggccggctaccatggggccaactgctct
gaggagatcaacgagtgcctgtccgacccctgccagaacgggggcacctgcatcgacctc
actaacacctacaagtgctcctgcccccggggaacacagggtgtgcactgtgagatcaat
gtggacgactgcagcccccctctagaccctgcctcccggagccccaggtgcttcaacaat
ggcacctgcgtcgaccaggtgggcggctacagctgcacctgtccacccggctttgtgggt
gagcggtgtgagggcgacgtcaacgagtgcctgtccaacccctgtgatgcacgtggcacc
cagaactgcgtgcagcgtgtcaacgacttccactgcgagtgccgccccggccacactggg
cgtcgctgtgagtctgtcatcaatggatgcaagggtaagccctgcaagaatgggggcact
tgcaatgtggcatccaacactgcccgcgggttcatctgcaagtgcccagcgggcttcgag
ggcgccacctgcgagaatgacgcccgcacctgtggcacgctgcgctgcctccatgggggc
acatgcatctctggcccacgcagccccacctgcctgtgcctggcgcccttcacgggcccc
gagtgccagttcccagccagcagcccctgcttgagcggcaacccctgctacaaccagggc
agctgtgagcccacatccgagagccccttctaccgctgcctgtgcccccccaagttcaac
gggctcctgtgccacatcctagactacagctttgggggtggtgctgggcgtgacatcccc
ccgccgcagatcgaggaggcctgcgagctgccggagtgccaggctgatgcgggcaacaag
gtctgcagcctgcagtgtaacaaccatgcctgtggctgggacgggggcgactgctccctc
aacttcaacgacccctggaagaactgcacgcagtccctgcagtgctggaagtacttcagc
gacggccgctgcgacagccagtgcaactcggccggctgcctcttcgacggcttcgactgc
cagcatgcagaaggccagtgcaaccccctgtatgaccagtactgcaaggaccacttcagc
gacgggcactgcgaccagggctgcaacagcgccgagtgcgagtgggatgggctggactgc
gcggagcacgttcccgagcggctggccgccggcacactggtgctggtggtgctgctgccg
ccccagcaactgcgcaaccactctctgcacttcctgcgggagctcagccgtgtgctgcac
accaacgtggtcttcaagagggatgcgcagggccaccagatgatcttcccctactacggc
cacgaggaggagctgcgcaaacaccccatcaagcgtgccgcgggctgggcggcacctggt
tccctgcttggccaggccactgcctccctgctccccggcagcagcaggcgccagcgcagg
gagctggaccccatggacatccgggggtctatcgtctacctggagatcgacaaccggcag
tgcctgcagtcctcctcccagtgcttccagagtgccaccgacgtggctgccttcctgggg
gcgctggcctcactgggcagcctcaatatcccctacaagatcgatgcggtgcagagtgag
actgtggagccgccgccgcctgctcagctgcacctcatgtatgtggccgcggccgccttc
gtgctgctcttcttcgtgggctgcggggtcctgctgtcccgcaagcgccggcggcagcat
ggccagctctggttccccgagggcttcaaggtgtccgaggccagcaagaagaagcggcgg
gagccccttggagaggactccgtgggcctcaagcctctgaagaacgcctcggacggcgcc
ctcatggacgagagccagaacgagtggggggatgagggcctggagaccaagaagttccgg
ttcgaggaacctgtggttcttcctgacctggatgaccagacagaccaccgacagtggacc
cagcagcacctggatgctgcagacctacgcatgtccgccatggcacccacaccaccccag
ggagaggtcgatgccgactgcatggatgtcaatgtccgtgggcccgatggcttcaccccg
ctcatgatcgcctcctgcagtggaggcggcctggagacaggcaacagtgaggaggaggag
gacgccccagccgtcatctccgacttcatctaccagggcgccagcctgcacaaccagacc
gaccgcacaggcgagactgccctgcacctggctgcccgttactcgcgctccgatgctgcc
aagcgcctgctggaggccagtgcagacgccaacatccaggacaacatggggcgcacccca
ctgcatgcggctgtttctgctgatgcacagggcgtcttccagatcctgatccggaaccga
gccacagacctggacgcccgcatgcatgacggcaccactcccttgatcctagctgcccgc
ctggctgtggagggcatgctggaggatctcatcaactctcacgcggacgtcaacgccgtg
gatgacctgggcaagtcggccctgcactgggctgctgctgtgaacaacgtggatgccgcc
attgtgctcctaaagaatggggccaacaaggacatgcagaacaacaaggaagagacgcct
ttgttcctggccgcccgggagggcagctatgagaccgccaaggtgctgctggaccacttt
gctaaccgggacatcaccgaccacatggaccgcctgcctcgggacatcgcacaggagcgc
atgcaccatgacatcgtgcggctgctggatgagcacaacctggtgcgcagcccccagcta
cacggggccgccctgggcagcacaccccgcctgtcgcccaccctctgctcgcccagtggc
tacctgggcaacctcaagcccagtgtgcagggcaagaaggcccgaaaacctagcaccaaa
ggcccagcctgtggcagcaaggaggccagggacctcaaggcacgcaggaagaagtcccag
gacagcaagggctgcctgctggacagctccagcatgctgtcgccagtggactccctcgag
tcaccgcatggctacctgtcggacgtggcctcgccacccctcctgccctcccccttccag
caatctccatccatgccgcttaaccacctgcccggcatgcctgatgcccacctgggcatc
agccatctgaatgtggcggccaagcctgagatggcagcgctgggtgggggcagccggctg
gcctttgagcctggccccccacggctctcccacttgcctgtggcctccagcactggcacg
atcctgggtgccagcagcacaggggctgtgaatttcactgtgggcggggctgcaggcttg
aatggccaatgtgagtggctctcccggctgcagagtggcatggtgcccagccagtacaac
ccgctgagaggggcggtggcacccggcacgctgagcacacaggcccccgctctccagcac
accatgatgggctcactgcccggcagtctctctgccagcgcactgtcccagatgatgagc
tatcagggcctgcccagtgcacggcatgccacccagcctcacctggtgcagccccagcag
gggccgcagcaaaacttgcagatgcagcaacagaacctgcagatgccagacatgcagcaa
ccccagagcctgcagccacctgcacagccacacctgggtgtgggcacagcagccagtggc
cacctgggtcggagcctcctgggaggggagccgagccaggatgtgcagccattgggcccc
agcaacctgacggtgcacaccatcctgccccaggagagccaggccttgcccacctcactg
ccatcctcactggtcccgcccatgaccactacccagttcctgaccccaccctcccagcac
agctactcctcctcgcctgtggacaatacccccagccaccagctgcaggtgcccgagcat
cccttcctcaccccgtccccagagtcccctgatcagtggtccagctcgtcgccacattcc
aacatctctgattggtccgagggcatctccagcccgcccaccaccatgcaatcccaggtc
acccacattccagaggcgttcaagtaa
DBGET
integrated database retrieval system
