Marmota marmota marmota (Alpine marmot): 107161117
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Entry
107161117 CDS
T09644
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma00010
Glycolysis / Gluconeogenesis
mmma00020
Citrate cycle (TCA cycle)
mmma00620
Pyruvate metabolism
mmma00785
Lipoic acid metabolism
mmma01100
Metabolic pathways
mmma01200
Carbon metabolism
mmma01210
2-Oxocarboxylic acid metabolism
mmma04066
HIF-1 signaling pathway
mmma04922
Glucagon signaling pathway
mmma05230
Central carbon metabolism in cancer
mmma05415
Diabetic cardiomyopathy
Module
mmma_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
107161117
00020 Citrate cycle (TCA cycle)
107161117
00620 Pyruvate metabolism
107161117
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
107161117
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
107161117
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
107161117
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
107161117
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
107161117
Enzymes [BR:
mmma01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
107161117
BRITE hierarchy
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
107161117
NCBI-ProteinID:
XP_015363095
Ensembl:
ENSMMMG00000004554
UniProt:
A0A8C5YWH6
LinkDB
All DBs
Position
Unknown
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLAGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKAHQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgcggcagtctcccgagttttggctggcgctgcccagaagccggca
agcagagtgctcgtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccggctggaagagggccctcctgtcacgacagtgctcaccagggaggat
gggctcaaatactataggatgatgcagactgtgcgccgaatggagttaaaggctcatcag
ctttataaacagaaaatcattcgtggtttttgtcacttgtgtgatggtcaggaagcctgc
tgtgtgggcctggaggctggcataaatcccacggaccacctcatcacagcctaccgggct
catggtttcacctttactcgaggcctttctgtccgagaaattcttgcagagctaacagga
cgaagaggaggctgtgctaaagggaaaggaggatcgatgcacatgtatgccaagaacttc
tatgggggcaatggcattgtgggagctcaggtgcccctgggagctgggattgctctggcc
tgcaagtacaatggaaaagatgaggtctgtttgactttatatggcgatggtgctgctaac
cagggtcagatatttgaagcttacaatatggcagcattgtggaaattaccttgtattttc
atctgtgagaataaccgatatggaatgggaacatctgttgagagagcagcagccagcact
gattactacaaaagaggcgattttattcctgggcttagggtggatggaatggatatcctg
tgtgtccgagaggcaacaaggtttgcggctgcctattgtagatctgggaagggtcccatc
ctgatggagctgcagacttaccgttatcatggacacagtatgagtgaccctggagtcagt
taccgcacacgagaagaaattcaggaagtaagaagtaagagtgaccctataatgcttctt
aaggatagaatggtgaacagcaatcttgccagtgttgaagaattaaaggaaattgatgtt
gaagtaaggaaagaaattgaggacgctgcccagtttgccacagctgatcctgagccacct
ttggaggaactaggctaccacatctacagcagcgatccaccctttgaagtgcgtggtgcc
aaccagtggatcaagtttaagtcagtcagttaa
DBGET
integrated database retrieval system
