| Entry |
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| Symbol |
Abcb1a, Abcb4, Evi32, Mdr1a, Mdr3, P-gp, Pgp, Pgy-3, Pgy3, mdr-3
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| Name |
(RefSeq) ATP-binding cassette, sub-family B member 1A
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| KO |
| K05658 | ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:7.6.2.2] |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
09131 Membrane transport
02010 ABC transporters
18671 (Abcb1a)
09150 Organismal Systems
09154 Digestive system
04976 Bile secretion
18671 (Abcb1a)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
18671 (Abcb1a)
09162 Cancer: specific types
05226 Gastric cancer
18671 (Abcb1a)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:mmu02000]
18671 (Abcb1a)
04147 Exosome [BR:mmu04147]
18671 (Abcb1a)
04090 CD molecules [BR:mmu04090]
18671 (Abcb1a)
Enzymes [BR:mmu01000]
7. Translocases
7.6 Catalysing the translocation of other compounds
7.6.2 Linked to the hydrolysis of a nucleoside triphosphate
7.6.2.2 ABC-type xenobiotic transporter
18671 (Abcb1a)
Transporters [BR:mmu02000]
ABC transporters, eukaryotic type
ABCB (MDR/TAP) subfamily
ABCB1, 4, 5 subgroups
18671 (Abcb1a)
Exosome [BR:mmu04147]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
18671 (Abcb1a)
CD molecules [BR:mmu04090]
Proteins
18671 (Abcb1a)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| LinkDB |
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| Position |
5:8617091..8798575
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| AA seq |
1276 aa
MELEEDLKGRADKNFSKMGKKSKKEKKEKKPAVSVLTMFRYAGWLDRLYMLVGTLAAIIH
GVALPLMMLIFGDMTDSFASVGNVSKNSTNMSEADKRAMFAKLEEEMTTYAYYYTGIGAG
VLIVAYIQVSFWCLAAGRQIHKIRQKFFHAIMNQEIGWFDVHDVGELNTRLTDDVSKINE
GIGDKIGMFFQAMATFFGGFIIGFTRGWKLTLVILAISPVLGLSAGIWAKILSSFTDKEL
HAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNNNLEEAKRLGIKKAITANISMGAAFL
LIYASYALAFWYGTSLVISKEYSIGQVLTVFFSVLIGAFSVGQASPNIEAFANARGAAYE
VFKIIDNKPSIDSFSKSGHKPDNIQGNLEFKNIHFSYPSRKEVQILKGLNLKVKSGQTVA
LVGNSGCGKSTTVQLMQRLYDPLDGMVSIDGQDIRTINVRYLREIIGVVSQEPVLFATTI
AENIRYGREDVTMDEIEKAVKEANAYDFIMKLPHQFDTLVGERGAQLSGGQKQRIAIARA
LVRNPKILLLDEATSALDTESEAVVQAALDKAREGRTTIVIAHRLSTVRNADVIAGFDGG
VIVEQGNHDELMREKGIYFKLVMTQTAGNEIELGNEACKSKDEIDNLDMSSKDSGSSLIR
RRSTRKSICGPHDQDRKLSTKEALDEDVPPASFWRILKLNSTEWPYFVVGIFCAIINGGL
QPAFSVIFSKVVGVFTNGGPPETQRQNSNLFSLLFLILGIISFITFFLQGFTFGKAGEIL
TKRLRYMVFKSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGATGSRLAVIFQNIANLG
TGIIISLIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENF
RTVVSLTREQKFETMYAQSLQIPYRNAMKKAHVFGITFSFTQAMMYFSYAACFRFGAYLV
TQQLMTFENVLLVFSAIVFGAMAVGQVSSFAPDYAKATVSASHIIRIIEKTPEIDSYSTQ
GLKPNMLEGNVQFSGVVFNYPTRPSIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLE
RFYDPMAGSVFLDGKEIKQLNVQWLRAQLGIVSQEPILFDCSIAENIAYGDNSRVVSYEE
IVRAAKEANIHQFIDSLPDKYNTRVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATS
ALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVIQNGKVKEHGTHQQLLAQK
GIYFSMVSVQAGAKRS |
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| NT seq |
3831 nt +upstreamnt +downstreamnt
atggaacttgaagaggaccttaagggaagagcagacaagaacttctcaaagatgggcaaa
aagagtaaaaaggagaagaaagaaaagaaaccagcagtcagtgtgcttacaatgtttcgt
tatgcaggttggctggacaggttgtacatgctggtgggaactctggctgctattatccat
ggagtggcgctcccacttatgatgctgatctttggtgacatgacagatagctttgcaagt
gtaggaaacgtctctaaaaacagtactaatatgagtgaggccgataaaagagccatgttt
gccaaactggaggaagaaatgaccacgtacgcctactattacaccgggattggtgctggt
gtgctcatagttgcctacatccaggtttcattttggtgcctggcagctggaagacagata
cacaagatcaggcagaagttttttcatgctataatgaatcaggagataggctggtttgat
gtgcatgacgttggggagctcaacacccggctcacagatgatgtttccaaaattaatgaa
ggaattggtgacaaaatcggaatgttcttccaggcaatggcaacattttttggtggtttt
ataataggatttacccgtggctggaagctaacccttgtgattttggccatcagccctgtt
cttggactgtcagctggtatttgggcaaagatattgtcttcatttactgataaggaactc
catgcttatgcaaaagctggagcagttgctgaagaagtcttagcagccatcagaactgtg
attgcgtttggaggacaaaagaaggaacttgaaaggtacaataacaacttggaagaagct
aaaaggctggggataaagaaagctatcacggccaacatctccatgggtgcagcttttctc
cttatctatgcatcatatgctctggcattctggtatgggacttccttggtcatctccaaa
gaatactctattggacaagtgctcactgtcttcttttccgtgttaattggagcattcagt
gttggacaggcatctccaaatattgaagccttcgccaatgcacgaggagcagcttatgaa
gtcttcaaaataattgataataagcccagtatagacagcttctcaaagagtgggcacaaa
ccagacaacatacaaggaaatctggaatttaagaatattcacttcagttacccatctcga
aaagaagttcagatcttgaagggcctcaatctgaaggtgaagagcggacagacggtggcc
ctggttggcaacagtggctgtggaaaaagcacaactgtccagctgatgcaaaggctctac
gaccccctagatggcatggtcagtatcgacggacaggacatcagaaccatcaatgtgagg
tatctgagggagatcattggtgtggtgagtcaggaacctgtgctgtttgccaccacgatc
gccgagaacattcgctatggccgagaagatgtcaccatggatgagattgagaaagctgtc
aaggaagccaatgcctatgacttcatcatgaaactgccccaccaatttgacaccctggtt
ggtgagagaggggcgcagctgagtgggggacagaaacagagaatcgccattgcccgggcc
ctggtccgcaatcccaagatccttttgttggacgaggccacctcagccctggatacagaa
agtgaagctgtggttcaggccgcactggataaggctagagaaggccggaccaccattgtg
atagctcatcgcttgtctaccgttcgtaatgctgacgtcattgctggttttgatggtggt
gtcattgtggagcaaggaaatcatgatgagctcatgagagaaaagggcatttacttcaaa
cttgtcatgacacagacagcaggaaatgaaattgaattaggaaatgaagcttgtaaatct
aaggatgaaattgataatttagacatgtcttcaaaagattcaggatccagtctaataaga
agaagatcaactcgcaaaagcatctgtggaccacatgaccaagacaggaagcttagtacc
aaagaggccctggatgaagatgtacctccagcttccttttggcggatcctgaagttgaat
tcaactgaatggccttattttgtggttggtatattctgtgccataataaatggaggctta
cagccagcattctccgtaatattttcaaaagttgtaggggtttttacaaatggtggcccc
cctgaaacccagcggcagaacagcaacttgttttccttgttgtttctgatccttgggatc
atttctttcattacattttttcttcagggcttcacatttggcaaagctggagagatcctc
accaagcgactccgatacatggttttcaaatccatgctgagacaggatgtgagctggttt
gatgaccctaaaaacaccaccggagcactgaccaccaggctcgccaacgatgctgctcaa
gtgaaaggggctacagggtctaggcttgctgtgattttccagaacatagcaaatcttggg
acaggaatcatcatatccctaatctatggctggcaactaacacttttactcttagcaatt
gtacccatcattgcgatagcaggagtggttgaaatgaaaatgttgtctggacaagcactg
aaagataagaaggaactagaaggttctggaaagattgctacggaagcaattgaaaacttc
cgcactgttgtctctttgactcgggagcagaagtttgaaaccatgtatgcccagagcttg
cagataccatacagaaatgcgatgaagaaagcacacgtgtttgggatcacgttctccttc
acccaggccatgatgtatttttcttatgctgcttgtttccggttcggtgcctacttggtg
acacaacaactcatgacttttgaaaatgttctgttagtattctcagctattgtctttggt
gccatggcagtggggcaggtcagttcattcgctcctgactatgcgaaagccacagtgtca
gcatcccacatcatcaggatcattgagaaaacccccgagattgacagctacagcacgcaa
ggcctaaagccgaatatgttggaaggaaatgtgcaatttagtggagtcgtgttcaactat
cccacccgacccagcatcccagtgcttcaggggctgagccttgaggtgaagaagggccag
acgctggccctggtgggcagcagtggctgcgggaagagcacagtggtccagctgctcgag
cgcttctacgaccccatggctggatcagtgtttctagatggcaaagaaataaagcaactg
aatgtccagtggctccgagcacagctgggcattgtgtcccaagagcccattctctttgac
tgcagcatcgcagagaacattgcctacggagacaacagccgggtcgtgtcttatgaggag
attgtgagggcagccaaggaggccaacatccaccagttcatcgactcgctacctgataaa
tacaacaccagagtaggagacaaaggcactcagctgtcgggtgggcagaagcagcgcatc
gccatcgcacgcgccctcgtcagacagcctcacattttacttctggacgaagcaacatca
gctctggatacagaaagtgaaaaggttgtccaggaagcgctggacaaagccagggaaggc
cgcacctgcattgtgatcgctcaccgcctgtccaccatccagaacgcggacttgatcgtg
gtgattcagaacggcaaggtcaaggagcacggcacccaccagcagctgctggcgcagaag
ggcatctacttctcaatggtcagtgtgcaggctggagcaaagcgctcatga |
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