Microcebus murinus (gray mouse lemur): 105870784
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Entry
105870784 CDS
T07238
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00010
Glycolysis / Gluconeogenesis
mmur00020
Citrate cycle (TCA cycle)
mmur00620
Pyruvate metabolism
mmur00785
Lipoic acid metabolism
mmur01100
Metabolic pathways
mmur01200
Carbon metabolism
mmur01210
2-Oxocarboxylic acid metabolism
mmur04066
HIF-1 signaling pathway
mmur04922
Glucagon signaling pathway
mmur05230
Central carbon metabolism in cancer
mmur05415
Diabetic cardiomyopathy
Module
mmur_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105870784 (PDHA2)
00020 Citrate cycle (TCA cycle)
105870784 (PDHA2)
00620 Pyruvate metabolism
105870784 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105870784 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105870784 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105870784 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105870784 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105870784 (PDHA2)
Enzymes [BR:
mmur01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105870784 (PDHA2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
105870784
NCBI-ProteinID:
XP_012619064
UniProt:
A0A8B7G9L9
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All DBs
Position
29:complement(18039504..18041021)
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AA seq
391 aa
AA seq
DB search
MRKMLAAFVSRVLSGVVRKPARQVLVASCNYSNDATFGIKQCELYRLEEGPPVTAVLTRE
DGLKYYRTMVVVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGIRPSDHVITSYR
AHGICYTRGLSVRAILAELTGRRGGCAKGKGGSMHMYATNFYGGNGIVGAQGPLGAGIAL
ACKYKGNDQVCLTMYGDGAANQGQIAEAFNMAALWKLPCVFICENNRYAMGTAVQRAAAS
TDYFKRGGFIPGLRVDGMDVLCVREATKFAADHCRSGKGPIVMELQTYRYHGHSMSDPGI
SYRKREEIQEVRNKSDPIMLLTDRMVTSKLASVEELKEIEAEVKKEIEEAAQFATTDPEP
PLDELGHHLFSNEPPFEVRGANPWIKYKSIS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggccgccttcgtctcccgcgttctgtcaggcgtggtccggaagcca
gcccgccaggtgctggtggcctcctgcaactactccaacgacgcgacgttcgggattaag
cagtgcgagctgtaccggctggaggagggcccgccggtgacggccgtgctgacgcgggag
gacgggctcaagtactaccgcaccatggtggtggtgcgccgcatggagctgaaggccgac
cagctgtacaagcagaagttcatccggggcttctgccacctgtgcgacgggcaggaggcg
tgctgcgtggggctggaggccggcatccggccctcggaccacgtgatcacgtcgtaccgc
gcccacggcatctgctacacgcgcgggctgtcggtgcgcgccatcttggccgagctgacg
ggccggcgcggcggctgcgccaagggcaagggcggctccatgcacatgtacgccaccaac
ttctacggcggcaacggcatcgtgggcgcgcagggcccgctgggcgccggcatcgcgctc
gcctgcaagtacaagggcaacgaccaggtgtgcctgaccatgtacggcgacggcgcggcc
aaccagggccagatcgccgaggccttcaacatggcggcgctgtggaagctgccgtgcgtc
ttcatctgcgagaacaaccgctacgccatgggcacggccgtgcagcgcgcggccgccagc
accgactacttcaagcgcggcggcttcatcccggggctgcgcgtggacggcatggacgtc
ctgtgcgtgcgcgaggccaccaagttcgccgccgaccactgccgctcgggcaaggggccc
atcgtgatggagctgcagacctaccgctaccacggccacagcatgagcgaccccggcatc
agctaccgcaagcgggaggagatccaggaggtgaggaacaagagcgaccccatcatgctg
ctcacggacaggatggtcaccagcaagctggccagcgtggaagagctgaaggagatcgag
gccgaggtgaagaaggagatagaagaggccgcccagttcgccacgaccgaccccgagccg
cccctggacgagctgggccaccacctcttcagcaacgagccgccgtttgaggtccgaggc
gcaaacccgtggatcaagtacaagtccatcagttaa
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