Microcebus murinus (gray mouse lemur): 105871813 Help Entry 105871813         CDS       T07238                                  Symbol LCK Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism mmur  Microcebus murinus (gray mouse lemur) Pathway mmur04064   NF-kappa B signaling pathway mmur04380   Osteoclast differentiation mmur04650   Natural killer cell mediated cytotoxicity mmur04658   Th1 and Th2 cell differentiation mmur04659   Th17 cell differentiation mmur04660   T cell receptor signaling pathway mmur05135   Yersinia infection mmur05166   Human T-cell leukemia virus 1 infection mmur05235   PD-L1 expression and PD-1 checkpoint pathway in cancer mmur05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:mmur00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     105871813 (LCK)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     105871813 (LCK)    04660 T cell receptor signaling pathway     105871813 (LCK)    04658 Th1 and Th2 cell differentiation     105871813 (LCK)    04659 Th17 cell differentiation     105871813 (LCK)   09158 Development and regeneration    04380 Osteoclast differentiation     105871813 (LCK)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     105871813 (LCK)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105871813 (LCK)   09171 Infectious disease: bacterial    05135 Yersinia infection     105871813 (LCK)   09163 Immune disease    05340 Primary immunodeficiency     105871813 (LCK)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmur01001]     105871813 (LCK)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:mmur03036]     105871813 (LCK) Enzymes [BR:mmur01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105871813 (LCK) Protein kinases [BR:mmur01001]  Non-receptor tyrosine kinases   SRC family    105871813 (LCK) Chromosome and associated proteins [BR:mmur03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     105871813 (LCK) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 Haspin_kinase SH3_16 SH3_3 Motif Other DBs NCBI-GeneID:  105871813 NCBI-ProteinID:  XP_012620863 Ensembl:  ENSMICG00000017802 UniProt:  A0A8B7GDW4 LinkDB All DBs Position 2:30477899..30504718 Genome browser AA seq 509 aa AA seqDB search MGCGCSSNPEDDWMENIDVCENCHYPIVPLDGKATLPMRNGSEVRDPLVTYEGSNPPASP MQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDKGGFYISPRITFTSLHELVRHYTNTPDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVQPDNCPEELYHLMMLCWKER PEDRPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtggctgcagctcaaaccctgaagatgactggatggagaacatcgatgtgtgt gagaactgccattacccgatagtcccgctggatggcaaggccacgctgcccatgcgaaat ggctctgaggtgcgggacccactggtcacctacgagggctccaacccaccagcctcccca atgcaagataacctggttattgccctgcacagctatgagccctctcatgatggagacctg ggcttcgagaagggtgaacagctccgcatcctggagcagagcggcgagtggtggaaggcg cagtccctgaccaccggccaggaaggcttcatccccttcaactttgtggccaaagcgaac agcctggagcccgagccctggttcttcaagaacctgagccgcaaggatgcggagcggcag ctgctggcgccggggaacacgcacggctccttcctgatccgggagagcgagagcaccgcg ggatcgttttcactgtcggtccgggacttcgaccagaaccagggagaggtggtaaaacat tacaagatccggaacctggacaagggcggcttctacatctcccctcgcatcaccttcacc agcctgcacgaactggtccgccactacaccaatactccagacgggctgtgcacgcggttg agccgcccctgccagacccagaagccccagaagccgtggtgggaggacgagtgggaggtt cccagggagacgctgaagctggtggagcggctgggggccggccagttcggggaggtgtgg atggggtactacaatgggcacacaaaggtggcagtgaagagcctgaagcagggcagcatg tcccctgacgccttcctggctgaggccaacctcatgaagcagctgcagcaccagcggctg gtccggctgtatgcggtggtcacccaggagcccatctacatcatcactgagtacatggag aatgggagtctggtggattttctcaagaccccaccaggcatcaagttgaccatcaacaaa ctcctggacatggcagcccaaatcgcagagggcatggcattcatcgaagagcggaattat atccaccgtgacctgcgggctgccaacatcctggtgtctgacaccctgagctgcaagatt gcagactttggcctagcacgcctcattgaggacaatgaatacacagccagggagggagcc aagtttcccattaagtggacagcaccagaagccattaactacgggacattcactatcaag tcggacgtgtggtcttttgggattctgctgacggagattgtcactcatggccgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggtg caacctgacaactgcccagaggaattgtaccacctcatgatgctgtgctggaaggagcgc ccagaggaccggcccacctttgactacctgcgcagtgtgctagaggacttcttcacggcc acagagggccagtaccagccgcagccttga

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