Microcebus murinus (gray mouse lemur): 105882374
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Entry
105882374 CDS
T07238
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mmur
Microcebus murinus (gray mouse lemur)
Pathway
mmur00010
Glycolysis / Gluconeogenesis
mmur00020
Citrate cycle (TCA cycle)
mmur00620
Pyruvate metabolism
mmur00785
Lipoic acid metabolism
mmur01100
Metabolic pathways
mmur01200
Carbon metabolism
mmur01210
2-Oxocarboxylic acid metabolism
mmur04066
HIF-1 signaling pathway
mmur04922
Glucagon signaling pathway
mmur05230
Central carbon metabolism in cancer
mmur05415
Diabetic cardiomyopathy
Module
mmur_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mmur00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
105882374 (PDHA1)
00020 Citrate cycle (TCA cycle)
105882374 (PDHA1)
00620 Pyruvate metabolism
105882374 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
105882374 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
105882374 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
105882374 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
105882374 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
105882374 (PDHA1)
Enzymes [BR:
mmur01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
105882374 (PDHA1)
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Gene cluster
GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
105882374
NCBI-ProteinID:
XP_012640125
Ensembl:
ENSMICG00000004067
UniProt:
A0A8B7HSC6
LinkDB
All DBs
Position
X:105944954..105959896
Genome browser
AA seq
390 aa
AA seq
DB search
MRKMLAAVSRVLSGAAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRA
HGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALA
CKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAAST
DYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVS
YRTREEIQEVRSKSDPIMLLKDRMVNNNLASVEELKEIDVEVRKEIEDAAQFATADPEPP
LEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1173 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgctgcccagaagccggca
agcagagtgctggtggcatcccgtaattttgcaaatgatgctacatttgaaattaagaaa
tgtgaccttcaccggctggaagagggtcctcctgtcacgacagtgctcaccagagaggat
gggctcaaatactacaggatgatgcagactgtgcgccgaatggagttaaaggcagatcag
ctgtataaacagaaaattattcgtggtttctgtcacttgtgtgatggtcaggaagcttgc
tgtgtgggcctggaggccggcataaatcccacagaccatctcatcacagcctaccgggct
cacggctttaccttcactcggggcctttctgtcagagaaattcttgcagagcttacagga
cgaaaaggaggttgtgctaaagggaaaggaggttcgatgcatatgtatgccaagaacttc
tacgggggcaatggcatcgtgggagcccaggtgcccctgggagctggtattgccttggcc
tgtaagtataatggaaaagatgaggtctgtctgactttatatggcgatggcgctgctaat
cagggtcagatattcgaagcttacaacatggcagctttgtggaaattgccctgtattttc
atctgtgagaataaccgctatggaatgggaacgtcagttgagagagcagcagccagcact
gactactacaagagaggcgatttcattcctgggctgagggtagatggaatggatatcctg
tgtgtccgagaggcaacaaggtttgcagctgcctattgtagatccgggaaggggcccatc
ctgatggagctacagacttaccgttaccatggacacagcatgagtgatcctggagtcagt
taccgtacacgagaagaaattcaggaagtaagaagtaagagtgaccctattatgcttctc
aaggatagaatggtgaacaacaatcttgccagtgttgaagaattaaaggaaattgacgta
gaagtgaggaaagaaattgaggatgccgcccagtttgccacggctgatcctgagccgcct
ttggaggaactcggttaccacatctacagcagcgacccaccttttgaagtccgtggtgcc
aatcagtggatcaagtttaagtcagtcagttaa
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