Mustela nigripes (black-footed ferret): 132007546
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Entry
132007546 CDS
T09425
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp00010
Glycolysis / Gluconeogenesis
mnp00020
Citrate cycle (TCA cycle)
mnp00620
Pyruvate metabolism
mnp00785
Lipoic acid metabolism
mnp01100
Metabolic pathways
mnp01200
Carbon metabolism
mnp01210
2-Oxocarboxylic acid metabolism
mnp04066
HIF-1 signaling pathway
mnp04922
Glucagon signaling pathway
mnp05230
Central carbon metabolism in cancer
mnp05415
Diabetic cardiomyopathy
Module
mnp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
132007546 (PDHA1)
00020 Citrate cycle (TCA cycle)
132007546 (PDHA1)
00620 Pyruvate metabolism
132007546 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
132007546 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
132007546 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
132007546 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
132007546 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
132007546 (PDHA1)
Enzymes [BR:
mnp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
132007546 (PDHA1)
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
MIF4G_like
Motif
Other DBs
NCBI-GeneID:
132007546
NCBI-ProteinID:
XP_059241729
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All DBs
Position
X:complement(109234276..109246957)
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AA seq
389 aa
AA seq
DB search
MRKMLAAVSRVLGVAQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDG
LKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAH
GFTFTRGLSVREILAELTGRRGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALAC
KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTD
YYKRGDFIPGLRVDGMDVLCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSY
RTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPL
EELGYHIYSSDPPFEVRGANQWIKFKSIS
NT seq
1170 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgctgtctctcgcgtgttgggcgtcgcccagaagccggcaagc
agagtgctcgtggcctcccgtaattttgcaaatgatgctacatttgaaattaagaaatgc
gatcttcaccggctggaggagggccctcctgtcaccacagtgctcaccagggaggacggg
ctcaagtactacaggatgatgcagacggtccgccggatggagttaaaggcagatcagctg
tacaagcagaagattattcgtggtttctgtcatttgtgtgatggtcaggaagcttgttgt
gtgggcttggaggctggcataaatcccacagaccatcttatcacagcctatcgggctcat
ggctttaccttcactcgtgggctttctgtccgagaaattctcgcagagcttacaggacga
agaggaggctgtgctaaagggaaaggtggatcgatgcacatgtacgccaagaacttctac
gggggcaacggcattgtcggcgcgcaggtgcccttgggagcggggattgccttggcctgt
aagtataacgggaaggatgaggtctgtctgactttgtatggcgacggcgctgctaatcag
ggtcagatatttgaagcttacaacatggcagctttgtggaaactgccgtgtattttcatc
tgtgagaacaaccgctatggaatgggaacatctgttgagagagcagcggccagcacggac
tactacaagagaggcgacttcatccctgggctgagggtagatggaatggacgtcttgtgt
gtccgggaggcaacaaggtttgcagctgcctactgtagatctggaaaggggcccatactg
atggagctacagacctaccgttaccacggacacagcatgagcgaccctggcgtcagttac
cgtacccgagaagagattcaggaagtacgaagtaagagtgaccctatcatgctgctcaag
gatagaatggtgaacagcaatctggccagcgttgaagaattaaaggaaattgatgttgaa
gtgaggaaggaaattgaggatgctgcccagtttgccactgcggatcccgaaccgcctttg
gaagagctgggttaccacatttacagcagcgacccgccttttgaagttcggggtgccaat
cagtggatcaagtttaagtccatcagttaa
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