Mustela nigripes (black-footed ferret): 132019632 Help Entry 132019632         CDS       T09425                                  Symbol ADCY6 Name (RefSeq) adenylate cyclase type 6   KO K08046   adenylate cyclase 6 [EC:4.6.1.1] Organism mnp  Mustela nigripes (black-footed ferret) Pathway mnp00230   Purine metabolism mnp01100   Metabolic pathways mnp01522   Endocrine resistance mnp04015   Rap1 signaling pathway mnp04022   cGMP-PKG signaling pathway mnp04024   cAMP signaling pathway mnp04062   Chemokine signaling pathway mnp04072   Phospholipase D signaling pathway mnp04114   Oocyte meiosis mnp04211   Longevity regulating pathway mnp04213   Longevity regulating pathway - multiple species mnp04261   Adrenergic signaling in cardiomyocytes mnp04270   Vascular smooth muscle contraction mnp04371   Apelin signaling pathway mnp04540   Gap junction mnp04611   Platelet activation mnp04713   Circadian entrainment mnp04714   Thermogenesis mnp04723   Retrograde endocannabinoid signaling mnp04724   Glutamatergic synapse mnp04725   Cholinergic synapse mnp04727   GABAergic synapse mnp04742   Taste transduction mnp04750   Inflammatory mediator regulation of TRP channels mnp04911   Insulin secretion mnp04912   GnRH signaling pathway mnp04913   Ovarian steroidogenesis mnp04914   Progesterone-mediated oocyte maturation mnp04915   Estrogen signaling pathway mnp04916   Melanogenesis mnp04918   Thyroid hormone synthesis mnp04921   Oxytocin signaling pathway mnp04923   Regulation of lipolysis in adipocytes mnp04924   Renin secretion mnp04925   Aldosterone synthesis and secretion mnp04926   Relaxin signaling pathway mnp04927   Cortisol synthesis and secretion mnp04928   Parathyroid hormone synthesis, secretion and action mnp04934   Cushing syndrome mnp04935   Growth hormone synthesis, secretion and action mnp04961   Endocrine and other factor-regulated calcium reabsorption mnp04962   Vasopressin-regulated water reabsorption mnp04970   Salivary secretion mnp04971   Gastric acid secretion mnp04972   Pancreatic secretion mnp04976   Bile secretion mnp05032   Morphine addiction mnp05163   Human cytomegalovirus infection mnp05166   Human T-cell leukemia virus 1 infection mnp05200   Pathways in cancer mnp05207   Chemical carcinogenesis - receptor activation mnp05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:mnp00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     132019632 (ADCY6)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     132019632 (ADCY6)    04371 Apelin signaling pathway     132019632 (ADCY6)    04072 Phospholipase D signaling pathway     132019632 (ADCY6)    04024 cAMP signaling pathway     132019632 (ADCY6)    04022 cGMP-PKG signaling pathway     132019632 (ADCY6)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     132019632 (ADCY6)   09144 Cellular community - eukaryotes    04540 Gap junction     132019632 (ADCY6)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     132019632 (ADCY6)    04062 Chemokine signaling pathway     132019632 (ADCY6)   09152 Endocrine system    04911 Insulin secretion     132019632 (ADCY6)    04923 Regulation of lipolysis in adipocytes     132019632 (ADCY6)    04912 GnRH signaling pathway     132019632 (ADCY6)    04913 Ovarian steroidogenesis     132019632 (ADCY6)    04915 Estrogen signaling pathway     132019632 (ADCY6)    04914 Progesterone-mediated oocyte maturation     132019632 (ADCY6)    04921 Oxytocin signaling pathway     132019632 (ADCY6)    04926 Relaxin signaling pathway     132019632 (ADCY6)    04935 Growth hormone synthesis, secretion and action     132019632 (ADCY6)    04918 Thyroid hormone synthesis     132019632 (ADCY6)    04928 Parathyroid hormone synthesis, secretion and action     132019632 (ADCY6)    04916 Melanogenesis     132019632 (ADCY6)    04924 Renin secretion     132019632 (ADCY6)    04925 Aldosterone synthesis and secretion     132019632 (ADCY6)    04927 Cortisol synthesis and secretion     132019632 (ADCY6)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     132019632 (ADCY6)    04270 Vascular smooth muscle contraction     132019632 (ADCY6)   09154 Digestive system    04970 Salivary secretion     132019632 (ADCY6)    04971 Gastric acid secretion     132019632 (ADCY6)    04972 Pancreatic secretion     132019632 (ADCY6)    04976 Bile secretion     132019632 (ADCY6)   09155 Excretory system    04962 Vasopressin-regulated water reabsorption     132019632 (ADCY6)    04961 Endocrine and other factor-regulated calcium reabsorption     132019632 (ADCY6)   09156 Nervous system    04724 Glutamatergic synapse     132019632 (ADCY6)    04727 GABAergic synapse     132019632 (ADCY6)    04725 Cholinergic synapse     132019632 (ADCY6)    04723 Retrograde endocannabinoid signaling     132019632 (ADCY6)   09157 Sensory system    04742 Taste transduction     132019632 (ADCY6)    04750 Inflammatory mediator regulation of TRP channels     132019632 (ADCY6)   09149 Aging    04211 Longevity regulating pathway     132019632 (ADCY6)    04213 Longevity regulating pathway - multiple species     132019632 (ADCY6)   09159 Environmental adaptation    04713 Circadian entrainment     132019632 (ADCY6)    04714 Thermogenesis     132019632 (ADCY6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     132019632 (ADCY6)    05207 Chemical carcinogenesis - receptor activation     132019632 (ADCY6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     132019632 (ADCY6)    05163 Human cytomegalovirus infection     132019632 (ADCY6)   09165 Substance dependence    05032 Morphine addiction     132019632 (ADCY6)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     132019632 (ADCY6)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     132019632 (ADCY6)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     132019632 (ADCY6) Enzymes [BR:mnp01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      132019632 (ADCY6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA TBK1_ULD GBR2_CC Motif Other DBs NCBI-GeneID:  132019632 NCBI-ProteinID:  XP_059258986 LinkDB All DBs Position 6:complement(84051930..84073135) Genome browser AA seq 1166 aa AA seqDB search MSWFSGLLVPKVDERKTAWGERNGQKRPRRGTRTGGFCTPRYMSCLREAQPPSPSPAAPP RCPWQDEAFIRRGGPGKGTELGLRAVALGFEDTEATAAVGVADVVPDGSPRRRWSCWRRL AQVFQSKQFRSAKLERLYQRYFFQMNQSSLTLLMAVLVLLTAVLLAFHAAPAPPQPAYVA LLACAATLFVALMVVCNRHSFRQDSMWVVSYVVLGILAAVQVGGALAADPRSPSVGLWCP VFFVYITYTLLPIRMRAAVFSGLGLSTLHLILAWQLNRGDAFLWKQLGANMLLFLCTNVI GICTHYPAEVSQRQAFQETRGYIQARLHLQHENRQQERLLLSVLPQHVAMEMKEDINTKK EDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCLR IKILGDCYYCVSGLPEARADHAHCCVEMGVDMIEAISLVREVTGVNVNMRVGIHSGRVHC GVLGLRKWQFDVWSNDVTLANHMEAGGRAGRIHITRATLQYLNGDYEVEPGRGGERNAYL KEQHIETFLILGASQKRKEEKAMLAKLQRTRANSMEGLVPRWAPDRAFSRTKDSKAFRQM GIDDSSKDNRGAQDALNPEDEVDEFLGRAIDARSIDQLRKDHVRRFLLTFQREDLEKKYS RKVDPRFGAYVACALLVFCFICFIQLLVFPHSTVMLGIYAGIFLLLLITVLTCAVSSCGS LFPKALRRLSRSIVRSRAHSTVVGIFSVLLVFTSAIANMFTCNHTPIRNCAARMLNVTPA DITTCHLQQLNYSLGLDAPLCEGTAPTCSFPEYFVGNMLLSLLASSVFLHISSIGKLAMV FVLGLIYLVLLLLGPPATIFDNYDLLLGVHGLASSNETFDGPDCPAAGRVALKYMTPVIL LVFALALYLHAQQVESTARLDFLWKLQATGEKEEMEELQAYNRRLLHNILPKDVAAHFLA RERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEIISEE RFRQLEKIKTIGSTYMAASGLNASTYDQAGRSHITALADYAMRLMEQMKHINEHSFNNFQ MKIGLNMGPVVAGVIGARKPQYDIWGNTVNVSSRMDSTGVPDRIQVTTDLYQVLAAKGYQ LECRGVVKVKGKGEMTTYFLNGGPPS NT seq 3501 nt NT seq  +upstreamnt  +downstreamnt atgtcgtggtttagtggcctcctggtccccaaagtggatgaacggaaaacagcctggggt gagcgcaatgggcagaagcgtccgcgccgtgggacccggacaggtggcttctgcacgccc cgctacatgagctgcctccgggaggcccagccccctagtcccagccccgccgctcccccg cggtgcccctggcaggatgaggccttcatccggaggggtggcccgggcaagggcactgag ctggggctgcgggcggtggccctgggctttgaggacacagaggcaacggcagcagtgggg gtggccgatgtggtgcccgacgggagccccaggcgtcggtggtcgtgctggcggcgtctg gcccaggtgttccagtccaagcagttccgctcggccaagctggagcgcctgtaccagcgg tacttcttccagatgaaccagagcagcctgacgctgctgatggccgtgctggtgctgctc acagcggtgctgctggccttccacgcggcgcctgcccctccgcagcctgcatatgtggcc ctgctggcctgcgccgccaccctcttcgtggcactcatggtggtgtgcaaccggcacagc ttccgccaggactccatgtgggtggtgagctacgtggtgctgggcatcctggcagctgtg caggtggggggcgccctggcggctgacccccgcagcccctctgttggcctctggtgcccc gtgttttttgtctacatcacctacacgctcctgcccatccgcatgcgggcggctgtcttc agtggcctgggcctctccaccctgcatctgatcttggcctggcaactcaaccgcggggac gccttcctctggaagcagctgggcgccaacatgctgctgttcctctgcaccaacgtcatt ggcatctgcacacactacccggcggaggtgtctcagcgccaggcctttcaggagacccgt ggttatatccaggcccggctgcacctgcagcacgagaaccggcagcaggaacggctgctg ctgtccgtgttgccccagcatgttgccatggagatgaaagaagatatcaacacaaagaaa gaagacatgatgttccacaagatctacatccagaagcatgacaatgtcagcatcctgttt gcggacattgaaggcttcaccagcctggcatcccagtgcaccgcacaggagctggtcatg accctgaacgagctctttgcccggtttgacaagctggctgcggaaaatcactgcctgagg atcaagatcttaggggactgttactactgtgtgtcggggctgccggaggcccgggcagac catgcccactgctgtgtggagatgggggtggacatgatcgaggccatctcgctggtgcgc gaggtgacaggtgtgaacgtgaacatgcgcgtgggcatccacagcgggcgtgtgcactgt ggtgtcctcggcctgcggaaatggcagttcgacgtgtggtccaacgacgtgacgctggcc aaccacatggaggcggggggccgggccggccgcatccacatcacccgggccacgctgcag tacctgaatggggactatgaggtggagccaggccgtggcggtgagcggaacgcatacctc aaggagcagcacatcgagaccttcctcatcctgggagccagccagaaacggaaagaggag aaggccatgctggccaagctgcagcggacgcgggccaactccatggaagggctggtgcca cgctgggcgcctgaccgcgccttctcccggaccaaggactccaaggctttccgtcagatg ggcattgatgattccagcaaggacaaccggggtgctcaagatgccctgaaccccgaggat gaagtagatgagttcctgggccgcgccatcgatgcccgcagcatcgaccagctacggaag gaccatgtgcgccgcttcctgctcactttccagagagaggatcttgaaaagaagtactcg aggaaggtggacccccgcttcggagcctacgtcgcctgtgcgctgttggtcttctgcttc atctgctttatccagcttctcgtcttcccacactccaccgtgatgcttggcatctatgcc ggtatcttcctgctgttgctgatcactgtgctgacctgtgccgtgtcctcctgtggctct ctcttccccaaggccctgcgccgtctttcccgcagcattgtccgctctcgggcacacagc actgtggttggcatcttttcagtcttgcttgtgttcacctctgccatcgccaacatgttc acctgcaaccacacccccatacgaaactgcgcagcccggatgctaaatgtgacacccgct gacatcaccacctgtcacctgcagcagctcaattactctctgggcctggacgctcccctg tgtgagggcaccgcacccacctgcagcttccctgagtacttcgttgggaacatgctgctg agtctcttggccagctctgtcttcctgcacatcagcagcattggaaagctggccatggtc tttgtcctggggctcatctatttggtgctgcttctgctgggccccccagccaccatcttt gacaactacgacttgctgcttggtgtccatggcttggcttcttccaatgagactttcgat gggccggactgcccagctgccgggagggtggcgctcaagtacatgacccccgtgattctg ctggtgtttgcgctggctctgtatctgcatgcccagcaggtggaatcaactgcccggctg gacttcctttggaaactacaggcaacaggggagaaggaggagatggaggaactgcaggca tacaaccggaggctgctgcataacattctgcccaaggacgtggctgcccacttcctggcc cgggagcgtcggaacgatgagctctactaccagtcgtgtgaatgtgtggccgtcatgttt gcctccattgccaacttttctgagttctatgtggagctggaggcaaacaatgagggtgtc gagtgcctgcggctgctcaatgagatcattgctgactttgatgagatcatcagcgaggag cgcttccggcagctggagaagatcaagacgatcgggagcacctacatggcggcctcagga ctgaacgccagcacgtacgatcaggccggccgctcccacatcactgccctggcagactat gccatgcggctcatggagcagatgaaacacatcaacgagcactccttcaacaatttccag atgaagattgggctgaacatgggcccagttgtggcaggcgtcattggggctcggaagccg cagtatgacatctgggggaacacagtgaatgtctctagccgtatggacagcacgggagtc cctgaccgaatccaggtgaccacggacttgtaccaggttctagctgccaaaggctaccag ctggagtgtcgaggggtggtcaaggtgaagggcaagggggagatgaccacctacttcctc aatgggggcccccccagttag

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