Mustela nigripes (black-footed ferret): 132025677
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Entry
132025677 CDS
T09425
Symbol
IKBKE
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform X1
KO
K07211
inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:
2.7.11.10
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp04620
Toll-like receptor signaling pathway
mnp04621
NOD-like receptor signaling pathway
mnp04622
RIG-I-like receptor signaling pathway
mnp04623
Cytosolic DNA-sensing pathway
mnp04625
C-type lectin receptor signaling pathway
mnp04657
IL-17 signaling pathway
mnp04936
Alcoholic liver disease
mnp05160
Hepatitis C
mnp05161
Hepatitis B
mnp05162
Measles
mnp05164
Influenza A
mnp05165
Human papillomavirus infection
mnp05167
Kaposi sarcoma-associated herpesvirus infection
mnp05168
Herpes simplex virus 1 infection
mnp05169
Epstein-Barr virus infection
mnp05171
Coronavirus disease - COVID-19
mnp05207
Chemical carcinogenesis - receptor activation
mnp05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
132025677 (IKBKE)
04621 NOD-like receptor signaling pathway
132025677 (IKBKE)
04622 RIG-I-like receptor signaling pathway
132025677 (IKBKE)
04623 Cytosolic DNA-sensing pathway
132025677 (IKBKE)
04625 C-type lectin receptor signaling pathway
132025677 (IKBKE)
04657 IL-17 signaling pathway
132025677 (IKBKE)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
132025677 (IKBKE)
09172 Infectious disease: viral
05161 Hepatitis B
132025677 (IKBKE)
05160 Hepatitis C
132025677 (IKBKE)
05171 Coronavirus disease - COVID-19
132025677 (IKBKE)
05164 Influenza A
132025677 (IKBKE)
05162 Measles
132025677 (IKBKE)
05168 Herpes simplex virus 1 infection
132025677 (IKBKE)
05167 Kaposi sarcoma-associated herpesvirus infection
132025677 (IKBKE)
05169 Epstein-Barr virus infection
132025677 (IKBKE)
05165 Human papillomavirus infection
132025677 (IKBKE)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132025677 (IKBKE)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
132025677 (IKBKE)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132025677 (IKBKE)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
132025677 (IKBKE)
Protein kinases [BR:
mnp01001
]
Serine/threonine kinases: Other
IKK family [OT]
132025677 (IKBKE)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TBK1_CCD1
Pkinase
TBK1_ULD
PK_Tyr_Ser-Thr
ABC1
Kinase-like
Pkinase_fungal
RH_dom
TPR_MLP1_2
MIP-T3_C
Motif
Other DBs
NCBI-GeneID:
132025677
NCBI-ProteinID:
XP_059269265
LinkDB
All DBs
Position
10:43557773..43581064
Genome browser
AA seq
719 aa
AA seq
DB search
MQSTVNYLWHTDDLLGQGATASVYKARNKKSGELVAVKVFNTASYLRPREVQVREFEVLR
KLNHQNIVKLFAVEETGGSRQKVLVMEYCSSGSLLSVLESPENAFGLPEEEFLVVLRCVV
AGMNHLRENGIVHRDIKPGNILRLLGEEGQSIYKLTDFGAARELDDDEKFVSVYGTEEYL
HPDMYERAVLRKPQQKTFGVTVDLWSIGVTLYHAATGSLPFIPFGGPRRNKEMMYRITTE
KPAGAIAGTQKQENGPLEWSYTLPVTCRLSLGLQSQLVPILANILEVEQAKCWGFDQFFA
ETSDILQRVVVHVFSLSQAVLHHVYIHAHNTIAIFLEAVYEQTRVAPQHQKFLFEGHFWV
LEPNLSAQHIAHTTASSPLTLLSTASETPMGLAFKDPAQDIPKFFPKVDLQADYTTAKSV
LGAGYQALWLARTLLAGQELMLRGLHWCVETLQATCRRTLEVTRMALLFLSSSLGTERFS
SVAGMTEMQELKKVTELRSRLRALAEALSRCSHSITESQTSLSNLRSELLKNRDQVHADR
SVQQIQFCLDKMNLIYKQFKKSRMRPGLGYNEEQIHKLDKVNFSRLAKRLLLQLFQETCV
QKYQTSLVTHGRWMREVHETRNHLRMVGCSVAAYNTEAQGAQESLSQILDRVSHQLLQDR
TKEVQVSPPLTAPYPSPALTDLVLQMQELCEEMKLLAFDLQDNNRVIEGLSWPPSAPDS
NT seq
2160 nt
NT seq
+upstream
nt +downstream
nt
atgcagagcaccgtcaattacctctggcacacggacgacctgctggggcagggggccact
gccagcgtgtacaaggcccgaaacaagaaatctggggagctggttgccgtgaaggtcttc
aacacggccagctacctgcgaccccgcgaggtgcaggtgagggagttcgaggtcctgcgg
aagctgaaccaccagaacatcgtcaagctctttgcggtggaggagacggggggcagccga
cagaaagtgctggtgatggagtactgctctagcgggagcctgctcagcgtgctcgagagc
cccgagaacgccttcgggctgcccgaggaggagtttctggtggtgctgcgctgtgtggtg
gccggcatgaaccacctgcgggagaatggcattgtccaccgagacatcaagcctggaaac
atcctgcgcctcctaggggaggaggggcagagcatctacaagctgacggacttcggggcc
gcccgggagctggatgatgatgagaagttcgtctctgtctatggcactgaggagtacctg
caccccgacatgtatgagcgggccgtgcttcgcaagccccagcagaagacattcggggtg
actgtggatctctggagtattggggtcaccctgtaccatgcggccaccggcagcctgccc
ttcatccccttcggggggccacggcgcaacaaggagatgatgtaccggattaccacggag
aagccagccggggccatcgcaggcactcagaagcaggagaacgggcccctggagtggagc
tacaccctccccgtcacctgccgactgtccttggggctgcagagccagctggtgcccatc
ctggccaacatcttggaggtggagcaggccaagtgctggggcttcgaccagttcttcgcg
gagaccagcgacatcctgcagcgagtcgtggtgcacgtgttctccctgtcccaggccgtc
ctgcaccacgtctacatccacgcccacaacacgatagccatctttctggaggccgtgtat
gagcagaccagggtggccccccaacaccagaagttcctcttcgagggtcacttctgggtc
ctcgagcccaacctgtcagcacaacacattgcccacacgaccgcaagcagccccctgacc
ctgttaagcacagccagtgagacccccatggggctggccttcaaggaccctgctcaggac
atccccaagttcttccccaaagtggacctgcaggcagattacaccaccgccaagagcgtc
ctgggcgctggctaccaggccctgtggctggcgcggaccctgctggccgggcaggagctc
atgcttcgggggctgcactggtgtgtggagacactccaggctacgtgcaggcggacgctg
gaggtcacgcggatggcgctcctcttcctcagcagcagtctgggcactgagaggttcagc
agtgtggccgggatgactgagatgcaggagctgaagaaggtcacggagctgaggtccagg
ctgcgggctttggcagaggccctctccagatgttcccacagtatcacagagtcccagaca
agcctgagcaacctaaggtctgagctgctgaagaaccgggatcaggtacatgcggacaga
agcgtccagcagattcagttttgtttggacaagatgaacctcatctacaaacagttcaag
aaatccagaatgaggccagggcttggctacaacgaggagcagattcacaagctggataag
gtgaattttagtcgtttagccaaaaggctcctcctgcagctgttccaggagacgtgtgtg
cagaagtatcagacgtccctggtcacgcacggcaggtggatgagggaggtgcacgagacc
aggaaccatttgcgcatggtcggctgttccgtggctgcctataacacggaagcccagggg
gcccaggagagtctcagccagatccttgaccgggtctctcaccagctccttcaggacaga
acaaaggaggttcaggtctccccacccctgacagccccctatcccagccctgcactgaca
gacctggttctccagatgcaggagctctgtgaggagatgaagctgctggcctttgacctt
caggacaacaatcgcgtcattgaagggttaagttggcccccgtcggctcctgactcctga
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