Microtus oregoni (creeping vole): 121435825
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Entry
121435825 CDS
T08307
Symbol
Hsd11b1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg00140
Steroid hormone biosynthesis
morg00980
Metabolism of xenobiotics by cytochrome P450
morg01100
Metabolic pathways
morg05204
Chemical carcinogenesis - DNA adducts
Module
morg_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
121435825 (Hsd11b1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
121435825 (Hsd11b1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
121435825 (Hsd11b1)
Enzymes [BR:
morg01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
121435825 (Hsd11b1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
FMO-like
Pyr_redox_2
2-Hacid_dh_C
Shikimate_DH
Motif
Other DBs
NCBI-GeneID:
121435825
NCBI-ProteinID:
XP_041491239
LinkDB
All DBs
Position
Unknown
AA seq
291 aa
AA seq
DB search
MAFLKKYLLPILVLFLGYYYSTVEEFRPEMLQGKKVIVTGASKGIGREMAYHLSQMGAHV
VLTARSEEGLQKVVSRCLELGAASAHYVAGTMEDLAFAEQFVHKAGKLMGGLDMLILNHI
TYSPLGFFRGDINSVRKAMEVNFFSYVVLSAAALPMLKQSSGSIAVVSSVAGKMAQPLIA
PYSATKFALDGFFSTVRQEYSLAKVNVSITLCVLGLIDTETAMKATSGVFTAEAAPKEEC
ALEIIKGTALRKEEVYYHKSSWVSLLLNNPGRRIMEYLSIRNYNLERFFEN
NT seq
876 nt
NT seq
+upstream
nt +downstream
nt
atggcattcctgaaaaaatacctgctacccattctggtgctcttcttgggctactactat
tctacagtagaagagttcagacccgaaatgctccaaggaaagaaagtgattgtcacgggg
gccagcaaagggatcggaagagaaatggcctatcatctgtcgcaaatgggagcccatgtg
gtactgaccgcgaggtcagaggaaggtctccagaaggtggtgtctcgctgccttgaactc
ggagcagcctctgcccactacgtggctggtactatggaagacttggcatttgcagagcag
tttgtccacaaagcgggaaagctcatgggtggattggacatgctcattctcaaccacatc
acttactcccctctgggtttcttccgtggtgacatcaactccgtgcgcaaagccatggag
gtcaacttcttcagctacgtggtcctgagtgctgcagccttgcccatgctgaagcagagc
agcggcagcattgctgtggtctcctccgtagctgggaaaatggcccagcctttgattgct
ccctactcggcaaccaagtttgctctggatgggtttttttctaccgtcagacaagaatac
tcactagccaaggtcaacgtgtccatcactctctgtgtccttggcctcatagacacagaa
acagctatgaaggcaacctctggcgtgttcacggccgaagccgcccccaaggaggaatgt
gctctggagatcatcaagggaacggctctgcggaaagaagaagtatactaccacaagtcg
agctgggtctctctcctgctaaacaacccaggaaggaggatcatggaatatttgtcaata
aggaattataacttggagagattttttgaaaactag
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