Microtus oregoni (creeping vole): 121446056
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Entry
121446056 CDS
T08307
Symbol
Acacb
Name
(RefSeq) acetyl-CoA carboxylase 2 isoform X1
KO
K01946
acetyl-CoA carboxylase / biotin carboxylase 2 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg00061
Fatty acid biosynthesis
morg00620
Pyruvate metabolism
morg00640
Propanoate metabolism
morg01100
Metabolic pathways
morg04152
AMPK signaling pathway
morg04910
Insulin signaling pathway
morg04920
Adipocytokine signaling pathway
morg04922
Glucagon signaling pathway
morg04931
Insulin resistance
morg04936
Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
121446056 (Acacb)
00640 Propanoate metabolism
121446056 (Acacb)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
121446056 (Acacb)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
121446056 (Acacb)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
121446056 (Acacb)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
121446056 (Acacb)
04922 Glucagon signaling pathway
121446056 (Acacb)
04920 Adipocytokine signaling pathway
121446056 (Acacb)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
121446056 (Acacb)
04931 Insulin resistance
121446056 (Acacb)
Enzymes [BR:
morg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
121446056 (Acacb)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
121446056 (Acacb)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
121446056 (Acacb)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
ATP-grasp_3
Dala_Dala_lig_C
Motif
Other DBs
NCBI-GeneID:
121446056
NCBI-ProteinID:
XP_041504335
LinkDB
All DBs
Position
Unknown
AA seq
2451 aa
AA seq
DB search
MVLLLFLTCLVFSCLTFSWLKFWGTMTDFKPLTSSKVEASLLSSEESDRSAEPLQKHGDC
SNLDTPDQEKPASHRGPRDASCQNSLPPSHQKPPRNPLSSNDTWPSPELQTNGTAAQGSE
VPGTNGLSSPARPPGQQAKPPSREDKKQAHIKRQLMTNFILGSFDDNSSDEDPSAGSFRD
SPRKGSRPSLGTLSLEAAPNSSDPESHTPTMRPSMSGLHLVKRGREHKKLDLHRDFTVAS
PAEFVTRFGGNRVIEKVLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKA
NAEYIKMADQYVPVPGGPNNNNYANVELIIDIAKRIPVQAVWAGWGHASENPKLPELLRK
HEIAFLGPPSEAMWALGDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDSRQQGKCISVPE
DVYERGCVKDVDEGLEAAEKVGFPLMIKASEGGGGKGIRKAERAEDFPMLFRQVQSEIPG
SPIFLMKLAQNARHLEVQVLADQYGNAVSLFGRDCSIQRRHQKIIEEAPATVAAPAVFEF
MEQCAVLLAKTVGYVSAGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQ
IAMGVPLHRLKDIRLLYGESPWGVTPISFESPPSPPIARGHVIAARITSENPDEGFKPSS
GTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSI
RGDFRTTVEYLVNLLETESFQNNDIDTGWLDHLIAERVQAEKPDIMLGVVCGALNVADAM
FRTCMTDFLHSLERGQVLPADSLLNIVDVELIYGGIKYILKVARQSLTVFVLIMNDCHIE
IDAHRLNDGGLLLSYNGSSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRCPSAGKLT
QYTVEDGDHVEAGSSYAEMEVMKMIMTLSVQDSGRVRYVKRPGVVLEAGCVVARLELDDP
SKVHAAQPFTGTLPAQQTLPILGAKLHQVFHSVLENLTNVMSGYCLPEPFFSTKLKEWVQ
KLMMTLRHPSLPLLELQEIMTSVAGRIPAPVEKAVRRVMAQYASNITSVLCQFPSQQIAT
ILDCHAATLQRKAEREVFFMNTQSIVQLVQRYRSGTRGYMKTVVLDLLRKYLNVEHHFQQ
AHYDKCVINLREQFKPDMTQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPTLSDELTSIL
NELTQLSRSEHCKVALRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLQKL
ILSETTIFDVLPTFFYHANKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCFVEFQFM
LPSSHPNRMAMPITVSNPDLLRHSTELFMDSGFSPLCQRMGAMVAFRKFEEFTRNFDDVI
SCFANVPKDTPLFRKACTSLYEDDGKSVREEPIHILNVAIQCAEHLEDDALVPILRTFVQ
SKKHILMDYGLRRITFLIAQEREFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRN
FDLTAVPCANHKMHLYLGAAKVKEGLEVTDHRFFIRAIIRHSDLITKEASFEYLQNEGER
LLLEAMDELEVAFNNTSVRTDCNHIFLNFVPTVIMDPLKIEESVRAMVMRYGSRLWKLRV
LQAEVKINIRQTTTGSAIPIRLFITNESGYYLDISVYKEVTDSRSGNIMFHSFGNKQGSL
HGMLINTAYVTKDLLQAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPEKYPKDILTYTE
LVLDSQGQLVEMNRLPGGNEVGMVAFKMRFKTPEYPDGRDAIVISNDITFQIGSFGIEED
FLYLRASEMARAEGIPKIYLAANSGARMGLAEEIKQIFQVAWVDPEDPHKGFRYLYLTPQ
DYTQISAQNSVHCKHIEDEGESRYVIMDVIGKSANLGVENLRGSGMIAGEASLAYEEIVT
ISMVTCRALGIGAYLVRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMH
NNGVSHVTVPDDFEGVCTILEWLSYIPKDNRSPVPIITPTDPIDREIEFIPSKAPYDPRW
MLAGKPHPTLKSSWQSGFFDHGSFMEIMAPWAQTVVTGRARLGGIPVGVIAVETRTVEVA
VPADPANLDSEAKIIQQAGQVWFPDSAYKTAQAIRDFNHEHLPLIIFANWRGFSGGMKDM
YEQMLKFGAYIVDGLRQYKQPILTYIPPYAELRGGSWVVLDSTINPLCIEMYADKESRGG
VLEPEGTVEIKFRKKDLVKTMRRIDPVCKKLMAQLGTAQLSDKDRKELEGQLKAREDLLF
PIYHQVAVQFADLHDTPGHMLEKGIISDVLEWKTARTFLYWRLRRLLLEAQVKQEILHAS
PDLSHEHTQSMLRRWFVETEGPVKAYQWDSNQVVVQWLEQHWSARDGLRSTIRENINYLK
RDTVLKTIQSLVQENPEVTMDCVAYLSQHLSSAERIQVAQLLSTTESPASP
NT seq
7356 nt
NT seq
+upstream
nt +downstream
nt
atggtcttgcttctctttttaacctgcctggttttctcctgcctgacattttcctggtta
aaattctgggggacaatgacagacttcaagccactcaccagcagtaaggtggaagcgagc
cttctttcaagcgaggaatcagacaggtcagctgagcccctgcaaaaacatggcgactgc
agcaatctggacactccagaccaggagaagccagcctcccacagaggccccagagatgcc
agttgtcagaactccctgcccccctcacaccagaagcctccgaggaatccactgtcttcc
aatgacacctggccctccccagaactccaaaccaatgggacagcagcccaaggctcagaa
gtcccaggtaccaatggtttatcctctcctgccaggcctccaggccagcaagccaaaccc
ccctccagagaggacaagaaacaggcacacatcaagagacagctgatgaccaacttcatc
ctgggctcctttgatgacaactcctctgatgaggaccccagtgctggctccttcagggat
tctccccggaagggcagcaggcccagcctgggcaccctgtctctggaggctgcaccaaac
tcaagtgaccctgagtcccacacacccactatgagacccagcatgtccggactccacctg
gtgaagagaggccgtgaacataagaaactggacctgcacagagatttcactgtagcgtcc
ccagctgagtttgtcacccgctttgggggcaacagggtcatcgagaaggtgctcattgcc
aacaacggcattgctgcggtcaagtgtatgcgctccatccgccgctgggcctatgagatg
ttccggaatgaacgtgccatccggtttgtggtcatggtgacccccgaggaccttaaagcc
aatgcagagtacatcaaaatggcggatcagtatgttcctgtcccgggaggacccaacaac
aacaactatgccaacgtggagctgatcatagacattgctaagagaatccctgtgcaggcc
gtgtgggctggctggggccatgcttcggaaaaccccaaacttccggagctgctacgcaag
cacgagattgctttcctaggtccccccagtgaggctatgtgggccctgggagataagatc
gcctctaccatcgtagcccagacattgcagatcccaaccctgccctggagtggaagtggt
ctcacagtggagtggacggaggacagccggcagcagggcaaatgcatcagtgtcccagaa
gatgtctacgaacgaggctgtgtgaaggatgtggatgaaggcttggaggcagctgaaaag
gttggatttccactgatgatcaaagcctccgaaggcggcggagggaaaggcatccgcaag
gctgagcgagcagaggacttccccatgcttttcagacaggtgcagagtgagatcccgggc
tcacctatctttctcatgaagctggcccagaatgcacggcacctggaggtgcaggtctta
gcagatcagtatggaaatgctgtgtcactgtttggacgtgactgctccatccagaggagg
caccagaagattatcgaggaggcgccagccaccgtagctgctccagctgtgtttgagttc
atggaacagtgtgctgtcctcctggccaagactgtgggctacgtcagtgccgggacggtg
gaatacctgtacagccaggacggcagcttccacttcttggagctaaacccgcgcttgcag
gtggagcatccgtgcactgaaatgattgcagatgtgaacctgcccgctgcgcagttgcag
atcgccatgggtgtgcccctgcaccggctgaaggacatacggcttctgtatggagaatct
ccctggggagtgacccctatttcttttgagagccctccgagtcctcccattgcccgaggt
catgtcattgcagccaggatcaccagtgaaaacccggatgagggttttaagccaagctcc
gggacagtccaggagctgaacttccgcagcaacaagaatgtgtggggctacttcagcgta
gcggctgccggaggcttgcatgagttcgccgattcccagtttgggcactgcttctcctgg
ggcgagaaccgtgaagaggccatttccaacatggtagtggctttaaaggagctgtccatt
cggggtgacttccggaccactgtggaatatcttgtgaaccttctggagaccgagagcttc
cagaacaatgatatcgacacggggtggctggaccatctcatcgctgagcgggtgcaggca
gagaagccggacatcatgctcggggtggtgtgtggggccttgaacgtggcggacgcgatg
ttcagaacctgcatgacggatttcttgcactccctggaaaggggtcaggtcctcccggct
gattcgctgctgaacattgtggatgttgagttgatttatggaggcattaagtacattctc
aaggtggcccggcagtccctgactgtcttcgttctcatcatgaacgactgccacatcgag
attgatgcccaccggctgaacgatggggggctgctcctgtcttacaacggcagcagttac
accacatacatgaaggaagaggtggacagttaccggatcactatcggcaataagacgtgt
gtgtttgaaaaggagaacgaccccacagtcctgagatgcccctcggctgggaagctgaca
cagtacacagtggaggatggagaccacgtagaagctgggagcagctacgctgagatggag
gtgatgaagatgatcatgaccctgagtgtgcaggacagtggcagggtgaggtacgtcaag
cgcccaggggtcgtactggaggccggctgcgtggtggcgaggctggaactcgatgaccct
tcaaaagtgcatgcggcgcagccattcacagggacactgcctgcccagcagaccctgccc
atcctcggggcgaagctgcaccaggtgttccacagcgtcttagaaaatctgaccaacgtc
atgagtggctactgcctgcccgagcctttcttcagcacaaagctgaaggagtgggtccaa
aagctcatgatgacgctccggcacccatccctacctctcctggagctgcaggagatcatg
accagcgtggcaggccgcatcccagcacccgtggagaaggccgtccgcagggtgatggcc
cagtatgccagcaacatcacttcagtgttgtgccagttccccagccaacagatagccacc
atcctggactgccacgccgccacgttgcagcgtaaggcagagcgcgaggtcttcttcatg
aacacacagagcatcgtgcagctggtccagaggtaccgcagcgggacccgtggctacatg
aagactgtggtgctggacctactgaggaagtatctgaatgtggaacatcatttccagcaa
gcccactatgacaagtgtgtcatcaacctaagggagcagttcaagccagacatgacccag
gtgctggactgcatcttctcacacgcacaggtggccaagaagaaccagctggtgatcatg
ctgatagatgaactctgtggcccagaccccaccctgtcagacgagctgacctccatcctc
aatgagctcacacagctgagcaggagcgagcactgcaaggtggccctcagagctaggcag
gtcctgattgcctcccacctcccctcctacgagctgcgacacaaccaggtagaatccatc
ttcctgtctgccatcgacatgtacggccaccagttctgcccggaaaacctccaaaaactg
atactttctgaaacgacgatattcgacgtcctgccaactttcttctatcacgctaacaag
gtcgtctgtatggcgtctctggaggtttacgtgcggagaggctacatcgcctatgagtta
aacagcctacagcaccgggagctcccagatggcacctgctttgtggagttccaattcatg
ctgccgtcttcccaccccaaccggatggccatgcctatcactgtctctaaccctgacctg
ctcagacacagcacggaactcttcatggacagtggcttctccccactgtgccagcgcatg
ggggccatggtcgccttcaggaaatttgaagagttcaccaggaactttgatgacgtcatc
tcctgctttgccaacgtgcctaaagacactcccctcttcaggaaggcctgcacctctctg
tatgaggatgatggcaagagcgttcgagaggagcccatccacatcctgaatgtggccatc
cagtgcgctgagcacctggaggacgacgcgctggtgccaattctccgtacctttgtgcag
tccaagaaacacatcctcatggactacggactccgaaggatcacattccttatcgcccaa
gagagagaatttcccaagttcttcacgttcagagcgagagacgagtttgcagaagaccgg
atttatcgccacttggagcccgccctggctttccagctggagctgagccggatgcggaac
tttgacctgaccgctgtgccctgtgccaaccataagatgcatctttacctgggtgccgcc
aaggtgaaggaagggctggaggtgacggaccacaggttcttcatccgcgccatcatccgg
cactcggatttgatcaccaaggaagcctccttcgagtacctgcagaatgaaggggagcgg
ttgctcctggaagccatggacgagctggaagtggcgttcaacaacaccagcgtgcgcacc
gactgcaaccacatcttcctcaactttgtgcccactgtcatcatggacccgctcaagatt
gaggagtcggtgcgagccatggtcatgcgctacggcagcaggctgtggaagctccgtgtg
ctgcaggcagaggtcaagatcaacatccgccagacgaccacaggcagtgctatccccatc
cgcctgttcatcaccaacgagtctggctactacctggacatcagcgtctacaaagaagtg
accgactccagatccggaaacatcatgtttcactccttcggcaacaagcaaggaagtctg
catggcatgctgatcaacacagcctacgtcaccaaagatctgctccaggccaagcgattc
caggcgcagtccctggggaccacctatgtgtatgacttcccggaaatgttcagacaggct
ctctttaaactgtggggctccccagaaaagtaccccaaagatatcctgacatacacagag
cttgtgttggactcccagggacagctggtggagatgaaccggcttcctggtgggaatgag
gtggggatggtggccttcaagatgaggtttaagaccccggagtatccagacggtcgggac
gccatcgtcatcagcaatgacatcaccttccaaattggctctttcggcatagaggaggac
ttcctgtatctgcgggcatctgagatggcccgggcagagggcatccccaaaatctacttg
gctgccaacagtggggcccgtatgggtctggccgaggagatcaagcagatattccaagta
gcttgggtggacccagaggacccccacaaaggatttagatacctgtacctgacgccccaa
gactacacccagatcagcgcccagaactccgtgcactgcaagcacattgaggatgaaggt
gaatccagatacgtcatcatggatgtcatagggaagagtgccaacctaggcgtggagaac
ctgaggggctcaggcatgatcgcaggagaggcctccctggcttacgaagaaattgttacc
atcagcatggtgacctgccgtgccctcggaattggggcctatttggtgaggcttggccag
cgggtgatccaagtggaaaattcccacatcatcctcactggagccagtgctctcaacaag
gtcctgggaagagaggtctacacgtccaacaaccagctgggaggtgtgcagatcatgcac
aacaacggggtctcccacgtcactgtgccagatgatttcgagggagtctgtaccattctg
gaatggctgtcgtatataccgaaggacaatcgcagcccagtccccatcatcactcctact
gaccccatcgacagggaaattgaattcatcccatccaaagctccctatgaccccaggtgg
atgcttgcagggaagcctcacccaactctgaagagttcctggcagagcggattcttcgac
catggcagtttcatggaaatcatggcaccctgggctcagaccgtggtgaccggacgagca
agattggggggcatccccgtgggggtgattgccgtggagactcggactgtggaggtggct
gtccctgccgaccctgccaacctggattctgaagccaaaatcatccagcaggcaggccag
gtgtggttcccagactctgcctacaagacagcacaggccatcagggatttcaaccacgag
cacctgcccctcatcatctttgccaactggagaggcttctcgggtggcatgaaggacatg
tatgagcagatgctgaagtttggagcctatattgtggacggcctccggcagtacaagcag
ccaattctcacctacatcccgccttatgctgagctccgtgggggctcatgggttgtcctg
gactccaccatcaaccccctgtgcatcgagatgtatgccgacaaagagagcaggggcggt
gttctagagccagagggcactgtggagattaagttccggaagaaagatctggtgaagacc
atgagaaggatagacccagtgtgcaagaagctcatggcacagctggggacagcccagctc
tctgacaaggaccgcaaggagctggagggccagctgaaggcccgagaggacctgctgttc
cccatctaccaccaggtggcagtgcagttcgctgacctgcacgacacgcccggccacatg
ctggagaagggaatcatctcggacgtgctggaatggaagactgcacgcaccttcttatac
tggaggctgcgccggctgctgctggaggctcaggtgaagcaggagattctccacgccagc
cccgacctgagccatgagcacacacagtccatgctacgacgctggtttgtggagactgag
ggccctgtcaaggcctaccagtgggacagcaaccaggtggtggtccagtggctggaacag
cactggtcagccagagatggcttgcgctccaccatccgtgagaacatcaattatctgaag
cgggacactgtcctcaagactatccagagtctggttcaggaaaacccagaggtgaccatg
gactgtgtggcgtacctgagccagcacctcagctcggctgagcggatacaggtggctcag
ctgttgtctaccacggagagcccggcttccccctga
DBGET
integrated database retrieval system
