Microtus oregoni (creeping vole): 121448144 Help Entry 121448144         CDS       T08307                                  Symbol Lck Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism morg  Microtus oregoni (creeping vole) Pathway morg04064   NF-kappa B signaling pathway morg04380   Osteoclast differentiation morg04650   Natural killer cell mediated cytotoxicity morg04658   Th1 and Th2 cell differentiation morg04659   Th17 cell differentiation morg04660   T cell receptor signaling pathway morg05135   Yersinia infection morg05166   Human T-cell leukemia virus 1 infection morg05235   PD-L1 expression and PD-1 checkpoint pathway in cancer morg05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:morg00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     121448144 (Lck)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     121448144 (Lck)    04660 T cell receptor signaling pathway     121448144 (Lck)    04658 Th1 and Th2 cell differentiation     121448144 (Lck)    04659 Th17 cell differentiation     121448144 (Lck)   09158 Development and regeneration    04380 Osteoclast differentiation     121448144 (Lck)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     121448144 (Lck)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     121448144 (Lck)   09171 Infectious disease: bacterial    05135 Yersinia infection     121448144 (Lck)   09163 Immune disease    05340 Primary immunodeficiency     121448144 (Lck)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:morg01001]     121448144 (Lck)   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:morg03036]     121448144 (Lck) Enzymes [BR:morg01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      121448144 (Lck) Protein kinases [BR:morg01001]  Non-receptor tyrosine kinases   SRC family    121448144 (Lck) Chromosome and associated proteins [BR:morg03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     121448144 (Lck) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 Haspin_kinase SH3_3 Kdo SH3_16 Motif Other DBs NCBI-GeneID:  121448144 NCBI-ProteinID:  XP_041507851 LinkDB All DBs Position Unknown AA seq 509 aa AA seqDB search MGCGCSSNPDDDWIENIDVCENCHYPIVPLDSKTTLPIRNDSEVRDPLVIYNGSIPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGEEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDNGGFYISPRITFPGLHELVRHYTNASDGLCTKLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLNINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER PEDRPTFDYLRSVLDDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtggctgcagctcaaaccctgatgatgactggatcgagaacattgacgtgtgt gagaactgccactatcccatagtcccgctggacagcaagaccacgctgcccattcggaat gactctgaggttcgggacccactggtcatctataatggctccatcccaccagcctcccca ctacaagacaacctggttattgccctgcacagctatgagccctctcatgatggagacctg ggctttgagaagggtgaacagctccgaatcctggagcagagcggtgagtggtggaaggct cagtccctgaccactggcgaagagggcttcatccccttcaatttcgtggcaaaagcaaac agcctggagcctgaaccctggttcttcaagaatctgagccgtaaagacgcggagcggcag cttttagcgcccgggaacacgcacggatccttcctgatcagggaaagtgaaagcaccgcg ggatctttttcactgtctgtcagagacttcgaccaaaaccagggagaagtggtgaaacat tacaagatccgtaacctagacaatggcggcttctacatctcccctcggatcacttttcct ggcctacacgagctggtccgccattacaccaatgcctcggacgggctgtgcacaaagtta agccgtccttgccagacccagaagccccagaagccgtggtgggaggatgaatgggaggtt cccagggagacactgaagttggttgagcggctgggagctggccagttcggggaagtgtgg atggggtactacaacgggcatacgaaggtggcagtgaagagcctgaagcaagggagcatg tcccctgatgccttcctggctgaagctaacctcatgaagcagctgcagcaccagcgactg gtccggctttatgcagtggtcacccaggagcccatctacataatcactgaatacatggag aacgggagcctagtagattttctcaagactccctctggcatcaaattgaacatcaacaaa ctcttggacatggcagcccagattgcagagggcatggcattcattgaagagcggaattac atccatcgcgacctgcgggctgctaacatcctggtgtctgacacactgagctgcaagatc gcagactttggcctggcacgcctcattgaggacaatgagtacacagccagggagggggcc aaatttcccattaaatggacagcaccagaagccattaactatgggaccttcaccatcaag tcggatgtgtggtctttcgggatcctactgacagagattgtcacccatggccgaatccct tacccaggaatgaccaaccctgaagtgattcagaatctggagcgagggtaccgaatggtc cgacctgacaactgtccggaggagctgtaccacctcatgatgctgtgctggaaggagcgt cccgaggaccggcccacatttgactaccttcgaagtgttctggatgacttcttcacagcc acagagggccagtaccagccccagccttga

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