Microtus oregoni (creeping vole): 121453608
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Entry
121453608 CDS
T08307
Symbol
Pdha2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg00010
Glycolysis / Gluconeogenesis
morg00020
Citrate cycle (TCA cycle)
morg00620
Pyruvate metabolism
morg00785
Lipoic acid metabolism
morg01100
Metabolic pathways
morg01200
Carbon metabolism
morg01210
2-Oxocarboxylic acid metabolism
morg04066
HIF-1 signaling pathway
morg04922
Glucagon signaling pathway
morg05230
Central carbon metabolism in cancer
morg05415
Diabetic cardiomyopathy
Module
morg_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
121453608 (Pdha2)
00020 Citrate cycle (TCA cycle)
121453608 (Pdha2)
00620 Pyruvate metabolism
121453608 (Pdha2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
121453608 (Pdha2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
121453608 (Pdha2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
121453608 (Pdha2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
121453608 (Pdha2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
121453608 (Pdha2)
Enzymes [BR:
morg01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
121453608 (Pdha2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
121453608
NCBI-ProteinID:
XP_041516425
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MRKMLAAVVSHVFSGATQKPAMRGLLASLNFSNDATCDIKKCDLYRLEEGPPTSTVLTRE
EALKYYRNMQVIRRMELKSDQMYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHIITSYR
AHGLCYTRGLSVKSILAELTGRRGGCAKGKGGSMHMYGKHFYGGNGIVGAQVPLGAGVAF
ACKYLGNGQVCLALYGDGAANQGQVAEAYNISALWKLPCVFICENNLYGMGTAIERAAAS
TDYHKRGNFIPGLRVNGMDILSVREATKFAADHCRSGKGPILMELQTYRYHGHSMSDPGV
SYRSREEVHNMRSKSDPIMLLRERMINNNLSNVEELKEIDADVRKEVEEAAQFAITDPEP
TLDELAHHLYYHNPPFEVRGTNKWIKYMSVS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctggccgctgtggtgtcccacgtgttttcgggagcgacccagaagcca
gccatgagagggctgctggcgtccctgaacttctccaacgacgccacctgcgacattaag
aaatgcgacctgtaccggctggaagagggccctccgacctccaccgtgctcacccgagag
gaggccctcaagtactaccggaacatgcaggtgattcggcgcatggagctgaagtctgac
cagatgtacaagcagaagttcattcgtggtttctgtcacctgtgtgacgggcaagaagcc
tgctgtgtggggctggaagcagggatcaatcccacagatcacattatcacgtcctaccgg
gctcatggcttgtgctacacacgggggctgtcggtcaaatccattctcgccgagctgact
ggacgccgaggaggctgtgccaagggcaaaggaggctcgatgcacatgtacggcaagcac
ttctacggaggcaatggcattgttggggcacaggtacccctgggagccggtgtcgctttt
gcctgtaaatacttgggaaatggtcaggtctgcctggctctgtatggcgatggtgcggct
aaccaggggcaggtggccgaagcttacaatatatcggccttgtggaaattaccttgtgtc
ttcatctgtgagaataacctatacggaatggggacggccattgagagagcagcagccagc
actgattatcacaagagaggcaattttatccctggactgagggtgaatgggatggatatc
ctctctgtccgtgaggcgaccaagtttgcggctgatcactgtagatctggaaaggggccc
attttgatggaactgcagacctaccgttatcatggacacagtatgagtgacccaggggtc
agttaccgttcacgagaagaagttcacaacatgcgaagcaagagtgatcctattatgctt
ctccgagagagaatgataaacaacaacctcagcaacgttgaagagttgaaggaaattgat
gcagatgtgagaaaagaagttgaggaagcagcccagtttgctataactgatccagaacca
actttggacgaattagctcatcacctctactaccacaatccaccatttgaagtacgtggt
acaaataaatggatcaagtatatgtctgtcagttag
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