Microtus oregoni (creeping vole): 121459308 Help Entry 121459308         CDS       T08307                                  Symbol Adcy1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism morg  Microtus oregoni (creeping vole) Pathway morg00230   Purine metabolism morg01100   Metabolic pathways morg01522   Endocrine resistance morg04015   Rap1 signaling pathway morg04020   Calcium signaling pathway morg04022   cGMP-PKG signaling pathway morg04024   cAMP signaling pathway morg04062   Chemokine signaling pathway morg04072   Phospholipase D signaling pathway morg04114   Oocyte meiosis morg04211   Longevity regulating pathway morg04213   Longevity regulating pathway - multiple species morg04261   Adrenergic signaling in cardiomyocytes morg04270   Vascular smooth muscle contraction morg04371   Apelin signaling pathway morg04540   Gap junction morg04611   Platelet activation morg04713   Circadian entrainment morg04714   Thermogenesis morg04720   Long-term potentiation morg04723   Retrograde endocannabinoid signaling morg04724   Glutamatergic synapse morg04725   Cholinergic synapse morg04727   GABAergic synapse morg04750   Inflammatory mediator regulation of TRP channels morg04911   Insulin secretion morg04912   GnRH signaling pathway morg04913   Ovarian steroidogenesis morg04914   Progesterone-mediated oocyte maturation morg04915   Estrogen signaling pathway morg04916   Melanogenesis morg04918   Thyroid hormone synthesis morg04921   Oxytocin signaling pathway morg04923   Regulation of lipolysis in adipocytes morg04925   Aldosterone synthesis and secretion morg04926   Relaxin signaling pathway morg04927   Cortisol synthesis and secretion morg04928   Parathyroid hormone synthesis, secretion and action morg04934   Cushing syndrome morg04935   Growth hormone synthesis, secretion and action morg04970   Salivary secretion morg04971   Gastric acid secretion morg04972   Pancreatic secretion morg04976   Bile secretion morg05032   Morphine addiction morg05142   Chagas disease morg05146   Amoebiasis morg05163   Human cytomegalovirus infection morg05166   Human T-cell leukemia virus 1 infection morg05200   Pathways in cancer morg05207   Chemical carcinogenesis - receptor activation morg05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:morg00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     121459308 (Adcy1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     121459308 (Adcy1)    04371 Apelin signaling pathway     121459308 (Adcy1)    04020 Calcium signaling pathway     121459308 (Adcy1)    04072 Phospholipase D signaling pathway     121459308 (Adcy1)    04024 cAMP signaling pathway     121459308 (Adcy1)    04022 cGMP-PKG signaling pathway     121459308 (Adcy1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     121459308 (Adcy1)   09144 Cellular community - eukaryotes    04540 Gap junction     121459308 (Adcy1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     121459308 (Adcy1)    04062 Chemokine signaling pathway     121459308 (Adcy1)   09152 Endocrine system    04911 Insulin secretion     121459308 (Adcy1)    04923 Regulation of lipolysis in adipocytes     121459308 (Adcy1)    04912 GnRH signaling pathway     121459308 (Adcy1)    04913 Ovarian steroidogenesis     121459308 (Adcy1)    04915 Estrogen signaling pathway     121459308 (Adcy1)    04914 Progesterone-mediated oocyte maturation     121459308 (Adcy1)    04921 Oxytocin signaling pathway     121459308 (Adcy1)    04926 Relaxin signaling pathway     121459308 (Adcy1)    04935 Growth hormone synthesis, secretion and action     121459308 (Adcy1)    04918 Thyroid hormone synthesis     121459308 (Adcy1)    04928 Parathyroid hormone synthesis, secretion and action     121459308 (Adcy1)    04916 Melanogenesis     121459308 (Adcy1)    04925 Aldosterone synthesis and secretion     121459308 (Adcy1)    04927 Cortisol synthesis and secretion     121459308 (Adcy1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     121459308 (Adcy1)    04270 Vascular smooth muscle contraction     121459308 (Adcy1)   09154 Digestive system    04970 Salivary secretion     121459308 (Adcy1)    04971 Gastric acid secretion     121459308 (Adcy1)    04972 Pancreatic secretion     121459308 (Adcy1)    04976 Bile secretion     121459308 (Adcy1)   09156 Nervous system    04724 Glutamatergic synapse     121459308 (Adcy1)    04727 GABAergic synapse     121459308 (Adcy1)    04725 Cholinergic synapse     121459308 (Adcy1)    04720 Long-term potentiation     121459308 (Adcy1)    04723 Retrograde endocannabinoid signaling     121459308 (Adcy1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     121459308 (Adcy1)   09149 Aging    04211 Longevity regulating pathway     121459308 (Adcy1)    04213 Longevity regulating pathway - multiple species     121459308 (Adcy1)   09159 Environmental adaptation    04713 Circadian entrainment     121459308 (Adcy1)    04714 Thermogenesis     121459308 (Adcy1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     121459308 (Adcy1)    05207 Chemical carcinogenesis - receptor activation     121459308 (Adcy1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     121459308 (Adcy1)    05163 Human cytomegalovirus infection     121459308 (Adcy1)   09174 Infectious disease: parasitic    05146 Amoebiasis     121459308 (Adcy1)    05142 Chagas disease     121459308 (Adcy1)   09165 Substance dependence    05032 Morphine addiction     121459308 (Adcy1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     121459308 (Adcy1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     121459308 (Adcy1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     121459308 (Adcy1) Enzymes [BR:morg01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      121459308 (Adcy1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom DUF6688 Motif Other DBs NCBI-GeneID:  121459308 NCBI-ProteinID:  XP_041524816 LinkDB All DBs Position Unknown AA seq 1118 aa AA seqDB search MAGAPRGQGGGGGAGEPGGAERAAGPGGRRGLRACGEEFACPELEALFRGYTLRLEQAAT LKALAVLSLLAGSLALAELLGAPGPAPGLAKGSHPVHCILFLALFVVTNVRSLQVSQLQQ VGQLALFFSLTFALLCCPFALGGPARGSAGGAVGAAVAEHGVWQLLLITFVSYALLPVRS LLVIGFGLVVAASHLLVTAALVPAKRPRLWRTLGANALLFVGVNMYGVFVRILTERSQRK AFLQARSCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLKPPERIFHKIYIQRHDN VSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCRRIKILGDCYYCVSGLT QPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVLCGVLGLRKWQYDVWSN DVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNTFLRTHNIETFFIVPSHR RKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFSNVMTCEDDDKRRALRT ASEKLRNRSSFSTNVVYTTPGTRVNRYISRLLEARQTELEMADLNFFTLKYKHAEREQKY HQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVAVLLLLVFSICFLVACILYLHITRVQ CFPGCLTIQIRTVLCVFIVVLIYSVALGCVVGCLPWAWSSQSNSSLVVLAAGGRRTVLPA LPCESAHHALLCCLVGTLPLAIFLRVSSLPKMILLSGLTTSYILVLELSGYTKVGGGALS GRSYEPIMAILLFSCTLALHARQVDVRLRLDYLWAAQAEEERDDMERVKLDNKRILFNLL PAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFNDFYIELDGNNMGVECLRLLNEII ADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTAGTRAKKSISSHLSTLADFAIDMFDV LDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVNVASRMDSTGVQGRIQVT EEVHRLLKRCSYQFVCRGKVSVKGKGEMLTYFLEGRTEGNSSHGRTFRLERRLCPYGRGG GQPRRPPLCPAAGLPIRPGLPPAPTSQHLPSTAAGKEA NT seq 3357 nt NT seq  +upstreamnt  +downstreamnt atggcgggggcgccgcgcggccaaggcggcggcggaggcgcgggcgagcccgggggcgca gagcgggcggctgggccgggcggacggcgcgggctccgggcgtgtggcgaggagttcgcg tgccccgagctggaggcgctgttccgcggctacacgctgcggctggagcaggcggccacg ctgaaggcgctggcggtgcttagcctgctggcgggctccctggcgctggctgaactgctg ggcgcgccgggtcccgcgcctggcctcgccaaggggtctcaccccgtgcactgcatcctc tttctggcgctgttcgtggtcaccaatgtccgatccctgcaggtgtcccagctgcagcag gtcggtcagctggcgctgttcttcagcctcaccttcgcgctactctgctgccccttcgcg ctgggtggcccggcgaggggttctgcgggaggcgcagtgggagccgcggttgctgagcat ggggtttggcaactccttttgatcaccttcgtatcctatgccttgctgcccgtgcgcagc ctactggtcatcggcttcgggcttgtggtggctgcctctcacttactggtcacagccgcc ttggtccctgccaagcgcccacgtctctggaggacgctcggtgccaatgccctgctcttc gtgggcgtgaacatgtatggcgtcttcgtgcgcatcttgacggagcgctcacagaggaag gcctttctgcaggctcgaagctgcatcgaggaccgactgcggctggaggatgagaacgag aagcaggagcggctgctcatgagcctcttgccccggaatgtcgccatggagatgaaggaa gacttcctgaagccccctgagaggattttccacaagatttacatccagaggcatgacaac gtgagcatcctgtttgcagacatcgtggggttcacaggtctggcatcccagtgcacggcc caggagctggtgaaactgctcaacgaactcttcggcaagttcgacgagttagccacggaa aaccactgtcgccgcatcaagatcctaggggactgctactactgtgtgtcgggactcacc cagcccaagactgaccacgcccattgctgtgtggagatgggacttgacatgatcgatacc atcacatctgtggccgaggctactgaagtagacctgaacatgcgtgtggggctgcacacc ggcagggtgctctgtggtgtcctgggcctacgcaagtggcagtatgatgtgtggtccaat gacgtgaccctagccaatgtcatggaggctgctggcttacctgggaaggttcacatcaca aagacgaccctcgcatgcctgaatggggactacgaggtagagccaggacatggccacgag aggaacaccttcctgagaacccacaacatcgagaccttctttattgtgccgtcccatcgg agaaagatatttccaggcttgattctctccgatataaaaccagccaagaggatgaagttc aagactgtctgctacctgctggtacagctcatgcattgccggaaaatgttcaaagcagag atccccttctccaatgtaatgacctgcgaggatgatgacaagcggagggcattgaggaca gcctcggagaagctcagaaaccgttcgtctttctctaccaacgtggtctacaccactccg ggcacacgtgtcaacaggtacattagccgtcttcttgaagcccgccagacagagctggag atggcagatctgaacttcttcaccctgaagtacaaacacgctgaacgagagcaaaaatac caccagcttcaggatgagtacttcaccagcgccgttgtcctcgccctcatcctggccgcc ttatttgggcttgtctaccttctgataattccacagagtgtggctgtcctgctgctgctg gtgttttctatctgcttcttggtggcctgtatcctgtacctgcacatcacgcgggtccag tgttttccagggtgcctgacgatccagatccgcactgttttgtgtgtattcatagtggtc ttaatctactcagtagccctaggatgtgtggtgggctgcctgccctgggcctggagctcc cagtccaacagctccctagtggtccttgcagctggcggccggcgcactgtgctgcctgcc ctgccctgtgagtctgcgcaccatgccctgctctgctgcctggtgggcaccctcccacta gccatattcctgcgggtgtcctccttgccaaagatgatcctgctgtccgggctgacaaca tcctacatccttgttctggagctcagtggatacaccaaggttgggggtggtgctctctcc gggcgtagctatgagccaatcatggctatcttgctattctcatgcacactggccctgcat gccaggcaagtggatgtcaggctacggctggactacctctgggcagcacaggcggaagag gagcgcgatgacatggagagagtgaagctggacaacaagaggatcctcttcaacctcctg ccggcccacgtggcgcagcattttctcatgtccaatccccggaatatggacctttattac cagtcctactcccaggtgggcgtcatgttcgcctccatccccaacttcaatgacttctat attgagctggacggcaacaatatgggggtcgagtgcctgcggctcctcaacgaaatcatt gccgactttgatgagctcatggacaaggacttttacaaggacctggagaagatcaagacc attgggagcacctatatggccgccgtggggctggcgcccacagcaggaaccagagctaag aagtccatctcttcccacctgagcacactggcagactttgccatcgatatgtttgacgtc ctggatgaaatcaactaccagtcctacaacgactttgttctccgagttggcatcaacgtt ggccctgtggtggctggagtgatcggcgctcggaggccccagtacgacatctgggggaac acagtcaacgtggccagtcggatggacagcactggggtccagggcagaatccaggtgact gaggaagtccaccggttgctgaagaggtgctcataccagtttgtgtgcagaggcaaagtc agcgtcaagggcaagggagagatgctcacgtacttcctagaaggcaggactgaaggaaac agttcccatggcaggacctttcgcctggagcggagattgtgtccttatggaagaggtgga ggccagcccagacggcccccactgtgtcctgcagctggactcccgatcagaccggggctt cccccagcccccactagccagcacctgccgtccacagcagcagggaaggaagcctag

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