Microtus oregoni (creeping vole): 121459335
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Entry
121459335 CDS
T08307
Symbol
Dot1l
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
morg
Microtus oregoni (creeping vole)
Pathway
morg00310
Lysine degradation
morg01100
Metabolic pathways
morg05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
morg00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
121459335 (Dot1l)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
121459335 (Dot1l)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
morg03036
]
121459335 (Dot1l)
Enzymes [BR:
morg01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
121459335 (Dot1l)
Chromosome and associated proteins [BR:
morg03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
121459335 (Dot1l)
HMT complexes
Dot1-containing complex
121459335 (Dot1l)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DOT1
Motif
Other DBs
NCBI-GeneID:
121459335
NCBI-ProteinID:
XP_041524902
LinkDB
All DBs
Position
Unknown
AA seq
1739 aa
AA seq
DB search
MGEKLELRLKSPVGAEPAVYPWPLPVYDKHHDAAHEIIETIRWVCEEIPDLKLAMENYVL
IDYDTKSFESMQRLCDKYNRAIDSIHQLWKGTTQPMKLNTRPSNGLLRHILQQVYNHSVT
DPEKLNNYEPFSPEVYGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCK
HHYGVEKADIPAKYAETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFV
NNFAFGPEVDHQLKERFANMKEAPRLHSRSGRIVSSKPFAPLNFRINSRNLSDIGTIMRV
VELSPLKGSVSWTGKPVSYYLHTIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNA
TTPTKVPESKAAATEAPADSGAEEEKSGVATVKKPSPSKARKKKLNKKGRKMAGRKRGRP
KKMSAANAERKSKKSQSALDLLHSSPPAPPSASPQDAYRAPHSPFYQLPPSTQLHSPNPL
LVAPTPPALQKLLESFKIQYLQFLAYTKTPQYKANLQQLLDQEKEKNTQLLDTAQQLFGH
CQTQKEEIHRLFQQKLDELGVKALTYNDLIQAQKEISAHNQQLREQSEQLEKDNSELRSQ
SLQLLRARCEELRLDWSTLSLENLRKEKQALRSQISEKQRHCLELQISIVELEKSQRQQE
LLQLKSCVPPDDALSLHLRGKGALGRELEADAGRLRLELDCAKISLPHLSSMSPELSMNG
HAAGYELCSTASRPSSKQNTPQYLASPLDQEVVPCTPSHSGRPRLEKLSGLTLPDYTRLS
PAKIVLRRHLSQDHTGVSKPAASELHPRAEHAKESTLPYQSPSLSNSMKLSPQDPLPASP
ATSPLTSEKGSEKGVKERAYSSHGETITSLPVSIPLSTVQPNKLPVSIPLASVVLPSRAE
RARSTPSPGPQPRDSSSTLEKQIGASAHGAGGSAAGSRSLTLAPTGFYTGSVAISGALAN
SPAPLVSGMETAVFDESSGPGSLFATMGSRSTPPQHPPLLPQPRNSGPASPAHQLSASPR
LSVTAQGPLPDTSKGELPSDPAVSDPENEAKRRIVFSIAANSSSKQSPSTRHSPLTSGTR
GDSVQSHGQDSRKRSRRKRASAGTLSLSTGVSPKRRALPAVAGLFSQSSGSPLNLNSMVS
NINQPLEITAISSPESSLKSSPTPYQDHDQPPVLRKERPLGLTNGAHYSPLTSDEEPGSE
DEPSSTRIERKIATISLESKSPPKTLENGGGLVGRKPAPSSEPVNSSKWKSTFSPISDLS
LAKAVDSPLQAGSALSHSPLFSFRPVLEEPAAEAKLPAHPRKSFAGSLTAAEGPSPGANP
PNGLAFSGGLAADLGLHSFNDGASLSHKGPEVASLSFPSQRGKDSTTETNPFLSRRQPEG
LGGLKGEGNAGKESGEAVPLCGSADKVALPHGSRAGKGRDRELDFKGGHNLFISAAAVPP
GGLLGGPGLVTVASSAGSTTPAAQAARPFLSTFTPGPQFTLGPMSLQANLGSVAGSSVLQ
SLFSTVPAAAGLVHVSSAAPRLTNSHTMGSFSSGVTGGTVGGVFTHAVPSASAHPFGAGV
SSGAVCSSATLGLSPLQAAASTSASSFQAAASVETRPPPPPPLLPPQHLGRPPAGPPVLH
APPPPNVTLPPPPALLASNSEPVLLQSLASLPANKAFLPPSSAASLQPANASLSVKLASL
PHKVSRPSFTVHHQPLPRLALAQAAPAAPQANSSGPSAVWVSLGMPPPYAAHLSGVKPR
NT seq
5220 nt
NT seq
+upstream
nt +downstream
nt
atgggcgaaaagctggagctgaggctcaagtcgccagtgggcgccgagcccgctgtctac
ccgtggccgctgccggtctacgacaagcaccacgatgctgctcatgagattatcgagact
atccggtgggtctgtgaggaaatcccagatctcaagctggccatggagaactatgtcctg
atcgactatgacaccaaaagttttgaaagcatgcagaggctgtgtgacaagtacaaccga
gccatcgacagcatccaccagctgtggaagggcaccacgcagcccatgaagctaaatact
cgaccttccaatgggctcctgcggcacatcctgcagcaggtgtacaaccactctgtgact
gaccctgagaagctcaacaactatgagcccttttcccctgaggtgtatggggagacctcc
ttcgacctggtcgcccagatgatcgacgagatcaagatgactgaggatgacctgtttgta
gacctgggcagtggtgtggggcaggttgtccttcaggttgctgcggccaccaactgcaaa
catcactacggagtggagaaagcggacatcccagccaagtacgcggagaccatggaccga
gagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaatacacactggaacga
ggtgacttcctctcagaggagtggagggaacggatcgccaacacgagtgttatatttgtg
aataactttgcctttggtcctgaggtggatcaccagctgaaggagcgattcgcaaacatg
aaggaagctcctaggctgcacagcagaagcggcagaatcgtctcctcaaagccctttgcc
cctctgaacttcaggatcaacagcaggaacttgagtgacatcggcaccattatgcgtgtg
gtggagctgtcacccctgaagggctccgtgtcatggactgggaagcccgtctcctactac
ctgcacactattgaccgcaccatacttgaaaattatttttctagtctgaaaaatccaaaa
ctcagggaggagcaggaagcagctcggcgccggcagcagcgagagaacaagagtaatgca
actacccccaccaaggtcccagagagcaaggcagctgccacggaggcccccgcggactct
ggtgctgaggaagaaaagtcaggtgtggccactgtcaaaaagccatctccctccaaagcc
cggaagaagaaactgaacaagaaagggaggaaaatggctggccggaagcgtggacggccc
aagaaaatgagtgctgcaaacgctgagcgcaagtccaagaagagccaaagcgcactggac
ctcctgcactcctctcctccagccccgccctcagcctcaccccaggatgcgtacagggca
cctcatagcccgttctaccagctacctccgagcacgcagctccactcccccaatccgttg
ctggtggcacccaccccgcctgcattacagaaacttttagagtccttcaagatccagtac
ctgcagttcctggcttacacgaagaccccacagtacaaggccaacctgcagcagcttctg
gaccaagagaaggagaagaacacacagctgctggacaccgcacagcagctcttcggtcat
tgccaaacccaaaaggaggagatccacagactgtttcagcagaaactggatgagttgggc
gtgaaggcgctgacctacaatgacctgattcaggcccagaaggagatctctgcccacaac
cagcagctgcgggagcagtcagagcagctggagaaggacaacagtgagctgcggagccag
agccttcagctgctcagagcccggtgtgaggagctgaggctggactggtccacactgtct
ctggagaacctgcggaaagagaaacaggccctgcggagccagatctcagagaagcagcga
cactgcctggagctgcagatcagcattgtggagctggagaagagccagcgacagcaggag
ctcctgcagttgaagtcctgtgtgccaccagatgatgctctgtccctgcatctgcgtggc
aagggtgccctgggccgcgagctggaggccgatgctgggcggttgcgtcttgagctggac
tgtgccaaaatctccctgccacacctcagcagcatgagccccgagctctccatgaatggc
catgccgctggctacgagctctgcagcacagctagtcggccctcgtccaagcagaacacc
ccccagtacctggcctcccccttggatcaggaggtcgtaccctgcacccccagccacagt
ggcaggcctcggctagaaaagttgtctggcctaactttgccagactacacccggttgtca
cctgccaagattgtgttgaggcggcacctgagccaggaccacactggggttagcaaacca
gctgccagtgagctacatcctcgggcagagcatgccaaggagagcacccttccctaccag
agccccagcttgtccaacagcatgaagctcagcccccaggatccactgcctgcctccccc
gcaacctcgccgctcacctcagagaagggcagtgaaaagggtgtgaaggagcgtgcctac
agcagccatggggagactatcaccagcctgcctgtcagcattccactcagcacagtgcag
cccaacaagctgcccgtcagcatcccactggccagtgtggtgctgcccagccgtgctgag
agggcgaggagcactcccagccctgggccacagccccgagactcctcatccacacttgaa
aagcagattggtgcttccgcccatggtgcagggggcagtgcagcagggagcaggagcctc
acactggcacccacaggtttctacactggttcggtggccatcagtggagccctggccaac
agcccagcgcctctggtatctggaatggaaactgctgtttttgatgagtcctctggccct
ggcagcctctttgccaccatgggatctcgcagcacaccaccacagcacccgcctctgcta
ccacagccccgcaactctggccctgcatctcctgcccaccaactttcggccagtccccgc
ctgagtgtgactgcccaaggtccgctgccggacaccagcaagggggagctgccttctgac
cctgccgtctcagacccggagaatgaagctaagaggaggattgtgttcagcattgcagcc
aattccagctctaagcagtcgccttctaccaggcatagccccttgacctctggaacccgt
ggggattctgtacagagccatgggcaggacagtcgtaaacgcagcagaaggaagcgtgca
tcagcgggaaccctcagccttagcacgggtgtgtcccccaagcgccgggctctgccagct
gtcgctggcctcttctcacagtcctcggggtctcccctcaacctcaactccatggtcagc
aacatcaatcagcccctggaaatcacagccatctcatcccctgagagttccctgaagagt
tccccgaccccctaccaggaccacgatcagcccccggtgctcaggaaggagcggccactg
ggcctgacgaatggggcccattactcaccactgacctcagatgaggagccaggctctgag
gatgagcccagcagtacccgaattgaaagaaaaattgcaacaatctccttagaaagcaaa
tctcctccgaagacgctggaaaatggtggtggtttggtgggaaggaagcctgcaccctcg
agtgaacctgtgaacagcagcaaatggaagtccactttctcacccatctccgacctcagc
ttggccaaggccgtggacagtccattgcaggctggctctgcactgagccacagccccctg
ttctctttccggccggtcctggaggagcctgcagctgaggccaagctccccgcccaccca
aggaaaagctttgccggctctctgactgcagccgagggcccgagccctggcgccaaccct
cccaacggcctggccttcagtgggggccttgctgcagacctcggtttacacagcttcaac
gacggtgcttccctctcccacaagggccctgaggtggccagcctgagcttcccatcacag
cggggcaaggatagtaccacggagactaatcccttcctcagtaggcggcagccggagggc
ctaggtggcctgaagggcgagggcaatgcaggcaaggagtcaggcgaggccgtgcccctg
tgtgggtctgcggacaaagttgcactgcctcatggcagcagggcaggcaaaggccgtgac
cgtgagctggacttcaagggtggccacaacctcttcatctctgctgcagccgtgcctccg
ggtggcctcctcggtggccctggtctagtgactgtggcttcctctgcgggcagtacaaca
cctgctgcccaggctgcccggccctttctgagcaccttcacccctgggccccagttcact
ctgggccccatgtccctgcaggccaacctgggctctgtggccggctcctctgtgctgcag
tccttgtttagcaccgtgcccgccgctgcaggcttggtgcatgtgtcatctgctgcgccc
cgactcaccaactcgcacaccatgggcagcttctcctccggggtgaccggtggaactgtt
ggaggtgtctttacccatgcggtgccttctgcctctgctcacccgtttggagctggtgtc
agtagcggggccgtgtgtagcagtgccacgctgggcctgagcccgctgcaggcggcagcc
agcacctcggcttcttcctttcaggctgcggcttcggtcgagactcggccgccccctcca
cctcccctacttcctcctcagcacctgggccggcctcctgcggggccacctgtcctccat
gcaccccctcctcctaacgtcaccttgcctcctccacctgcgctgctggcttctaactcc
gagccagtgcttctgcagagcctggcctccctcccggctaacaaagctttcttacccccc
tcctctgccgcttctctgcagcctgctaacgcctctctgtctgtcaagctcgcctccctt
ccacacaaggtctcccgcccctccttcacggtgcaccaccagcccctgccccggctggcc
ctggcgcaggctgcgcccgccgccccacaggccaactcctcggggccatctgctgtgtgg
gtttcccttggcatgccgcctccttatgctgcgcacctttcgggggttaagcctcgataa
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integrated database retrieval system
