Mycobacterium paragordonae: C0J29_04585
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Entry
C0J29_04585 CDS
T06847
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
mpag
Mycobacterium paragordonae
Pathway
mpag00860
Porphyrin metabolism
mpag01100
Metabolic pathways
mpag01110
Biosynthesis of secondary metabolites
mpag01120
Microbial metabolism in diverse environments
mpag01240
Biosynthesis of cofactors
Module
mpag_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
mpag_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
mpag00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
C0J29_04585
Enzymes [BR:
mpag01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
C0J29_04585
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
C0J29_04585
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Gene cluster
GFIT
Motif
Pfam:
HEM4
TP_methylase
Motif
Other DBs
NCBI-ProteinID:
AYE94175
UniProt:
A0A386U185
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Position
998844..1000508
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AA seq
554 aa
AA seq
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MTRGRKPTPGRITFVGSGPGDPGLLTTRAATVLANAALVFTDPDVPEAVLALIGKDLPPV
SGPAPAESAPASSDTAASSSSPETVAAVISAGPDVRPALGDPAEVAKTLTAEARSGVDVV
RLVAGDPLSVDAVITEVNAVARAHLHVEIVPGLAASSAVPTYAGLPLGSSHTVADVRGDV
DWEALAAAPGPLILQATASHLADAARTLIDHELSDSTPCVVTAQGTTCQQRSVETTLQGL
TDPAVLGGGTDPAGPLTGPLVVTIGKTVASRAKLNWWESRALYGWTVLVPRTKDQAGEMS
ERLTSYGALPIEVPTIAVEPPRSPAQMERAVKGLVDGRFQWVVFTSTNAVRAVWEKFGEF
GLDARAFSGVKIACVGEATADRVRAFGISPELVPSGEQSSMGLLDEFPPYDSIFDPVNRV
LLPRADIATETLAEGLRERGWEIEDVTAYRTVRAAPPPASTREMIKTGGFDAVCFTSSST
VRNLVGIAGKPHARTIIACIGPKTAETAAEFGLRVDVQPETAAVGPLVDALAEHAARLRA
EGALPPPRKKSRRR
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
atgacgcgagggcgtaagccgacaccgggccgcatcacttttgtgggttctggtccaggt
gaccccggtctactgaccactcgggccgccacggtgctggcgaatgcggccctggtattc
accgaccccgacgtgcccgaggcggtgctggcgctgatcggcaaggatctgccgccggtt
tccggtccggcccccgctgaatctgcgccggccagctccgataccgccgccagttcgtcg
agcccggaaaccgtcgccgcggtgatttcggcaggccccgacgttcgtcccgcgctcggc
gatcccgccgaggtcgctaaaacgctgacggcagaggcccgctcgggcgtcgacgtggtg
cggttggtggccggcgacccgctctcggtggacgcggtgatcaccgaggtgaacgccgtc
gcccgggcgcacctgcatgtcgagatcgtgcccggcctggccgccagcagcgcggtcccg
acctacgccgggttgccgctgggttcctcgcacaccgtcgccgacgtgcgtggtgacgtc
gactgggaggcgctggccgccgcaccggggccgctgatcctgcaggccacggcgtcgcac
ctggcggacgccgcgcgcaccctgatcgaccacgagctgtccgacagcaccccttgcgtg
gtgaccgcgcagggcaccacctgccagcaacggtcggtggagaccacgctgcagggtctg
accgaccccgccgtcctgggcggcggcaccgacccggccggcccgttgactggcccgctg
gtggtcaccatcggcaagacggtggccagccgggcgaagctgaactggtgggagagccgg
gcgctgtacggctggaccgtgttggtgccccgcaccaaggaccaggccggcgagatgagc
gagcggctgacgtcctacggcgcgctgccgatcgaggtgccgaccatcgccgtcgagccg
ccgcgcagccccgcgcagatggaacgcgcggtcaagggtctggtggacggccgtttccag
tgggtggtgttcacctcgaccaacgccgtgcgtgcggtgtgggagaagttcggcgagttc
ggtctggacgcccgggcgttctccggggtgaagatcgcctgcgtcggcgaggcgacggcg
gaccgggtgcgggcgttcgggatcagccccgaactggtgccgtccggcgagcagtcgtcg
atgggtctgctggacgaattcccgccctacgacagcattttcgacccggtgaaccgggtg
ctgctgccacgcgcggacatcgccaccgagacgctggccgagggcctgcgtgaacgtggg
tgggagatcgaggacgtcaccgcctaccggaccgtgcgggccgccccgccgccggcgtcc
acccgggagatgatcaagaccggtggcttcgacgcggtgtgcttcacctccagctcgacc
gtccggaatctggtcggtattgccggaaagccgcacgcgcgcaccatcatcgcctgcatc
ggcccgaagaccgccgagaccgcggccgagttcggcctgcgggtggatgtccagccggag
accgccgcggtgggtccgttggtcgacgcgctggccgaacacgccgcccggttgcgcgcc
gaaggcgcgttgcccccgccgcgcaagaagagccgccggcgatga
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