KEGG   Mustela putorius furo (domestic ferret): 101670064
Entry
101670064         CDS       T07239                                 
Symbol
PTEN
Name
(RefSeq) phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN
  KO
K01110  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67]
Organism
mpuf  Mustela putorius furo (domestic ferret)
Pathway
mpuf00562  Inositol phosphate metabolism
mpuf01100  Metabolic pathways
mpuf01521  EGFR tyrosine kinase inhibitor resistance
mpuf04068  FoxO signaling pathway
mpuf04070  Phosphatidylinositol signaling system
mpuf04071  Sphingolipid signaling pathway
mpuf04115  p53 signaling pathway
mpuf04140  Autophagy - animal
mpuf04150  mTOR signaling pathway
mpuf04151  PI3K-Akt signaling pathway
mpuf04218  Cellular senescence
mpuf04510  Focal adhesion
mpuf04931  Insulin resistance
mpuf05165  Human papillomavirus infection
mpuf05166  Human T-cell leukemia virus 1 infection
mpuf05200  Pathways in cancer
mpuf05206  MicroRNAs in cancer
mpuf05208  Chemical carcinogenesis - reactive oxygen species
mpuf05213  Endometrial cancer
mpuf05214  Glioma
mpuf05215  Prostate cancer
mpuf05218  Melanoma
mpuf05222  Small cell lung cancer
mpuf05224  Breast cancer
mpuf05225  Hepatocellular carcinoma
mpuf05230  Central carbon metabolism in cancer
mpuf05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
mpuf05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mpuf00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    101670064 (PTEN)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    101670064 (PTEN)
   04070 Phosphatidylinositol signaling system
    101670064 (PTEN)
   04071 Sphingolipid signaling pathway
    101670064 (PTEN)
   04151 PI3K-Akt signaling pathway
    101670064 (PTEN)
   04150 mTOR signaling pathway
    101670064 (PTEN)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    101670064 (PTEN)
  09143 Cell growth and death
   04115 p53 signaling pathway
    101670064 (PTEN)
   04218 Cellular senescence
    101670064 (PTEN)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    101670064 (PTEN)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    101670064 (PTEN)
   05206 MicroRNAs in cancer
    101670064 (PTEN)
   05208 Chemical carcinogenesis - reactive oxygen species
    101670064 (PTEN)
   05230 Central carbon metabolism in cancer
    101670064 (PTEN)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    101670064 (PTEN)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    101670064 (PTEN)
   05214 Glioma
    101670064 (PTEN)
   05218 Melanoma
    101670064 (PTEN)
   05215 Prostate cancer
    101670064 (PTEN)
   05213 Endometrial cancer
    101670064 (PTEN)
   05224 Breast cancer
    101670064 (PTEN)
   05222 Small cell lung cancer
    101670064 (PTEN)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101670064 (PTEN)
   05165 Human papillomavirus infection
    101670064 (PTEN)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    101670064 (PTEN)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    101670064 (PTEN)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    101670064 (PTEN)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mpuf01009]
    101670064 (PTEN)
Enzymes [BR:mpuf01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     101670064 (PTEN)
    3.1.3.48  protein-tyrosine-phosphatase
     101670064 (PTEN)
    3.1.3.67  phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase
     101670064 (PTEN)
Protein phosphatases and associated proteins [BR:mpuf01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Dual specificity phosphatases)
   Phosphatase and Tensin homologs (PTEN)
    101670064 (PTEN)
SSDB
Motif
Pfam: PTEN_C2 DUF3256
Other DBs
NCBI-GeneID: 101670064
NCBI-ProteinID: XP_004764525
UniProt: A0A8U0N2A7
LinkDB
Position
Unknown
AA seq 215 aa
MSNLKMEIMLCTSKGPWLWAGAPHVLLPSRSSPLTFFSSNSGPTRWEDKFMYFEFPQPLP
VCGDIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEKTSEEVENGSLCDQGIISICSIER
ADNDKEYLVLTLTKNDLDKANKDKANQYFSPNFKVKLYFTKTVEEPSNPEASSSTSLTPD
VSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV
NT seq 648 nt   +upstreamnt  +downstreamnt
atgtccaatctaaaaatggagataatgttatgtacctccaaagggccctggctctgggcg
ggcgcccctcacgttcttctcccctcacgttcttctcccctcacgttcttctcctccaat
tcaggacccacacgatgggaagacaagttcatgtactttgagttccctcagcctttgcct
gtgtgtggtgacatcaaagtagagttcttccacaagcagaacaagatgctaaaaaaggac
aaaatgtttcacttttgggtaaacacattcttcataccaggaccagagaaaacctcagaa
gaagtagaaaatggaagtctctgtgatcaaggaattattagtatttgcagtatagaacgt
gcagataatgacaaggaatatctagtactcactctaacaaaaaatgatctcgacaaagca
aacaaagacaaggccaaccaatacttttctccaaattttaaggtgaagctgtacttcacg
aaaacagtagaggagccgtcaaatcccgaggctagcagttcaacttctttaacaccagat
gttagtgacaatgaacctgatcattatagatattctgacaccactgactctgatccagag
aatgaaccttttgatgaagatcagcatacacaaattacaaaagtctga

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