Mustela putorius furo (domestic ferret): 101689486
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Entry
101689486 CDS
T07239
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X2
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
mpuf
Mustela putorius furo (domestic ferret)
Pathway
mpuf00562
Inositol phosphate metabolism
mpuf01100
Metabolic pathways
mpuf04014
Ras signaling pathway
mpuf04015
Rap1 signaling pathway
mpuf04020
Calcium signaling pathway
mpuf04024
cAMP signaling pathway
mpuf04070
Phosphatidylinositol signaling system
mpuf04919
Thyroid hormone signaling pathway
mpuf04933
AGE-RAGE signaling pathway in diabetic complications
mpuf05205
Proteoglycans in cancer
Module
mpuf_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
mpuf00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
101689486 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
101689486 (PLCE1)
04015 Rap1 signaling pathway
101689486 (PLCE1)
04020 Calcium signaling pathway
101689486 (PLCE1)
04070 Phosphatidylinositol signaling system
101689486 (PLCE1)
04024 cAMP signaling pathway
101689486 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
101689486 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
101689486 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
101689486 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mpuf04131
]
101689486 (PLCE1)
Enzymes [BR:
mpuf01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
101689486 (PLCE1)
Membrane trafficking [BR:
mpuf04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
101689486 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
101689486 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
GDPD
Motif
Other DBs
NCBI-GeneID:
101689486
NCBI-ProteinID:
XP_004749694
Ensembl:
ENSMPUG00000017136
UniProt:
A0A8U0MPF9
LinkDB
All DBs
Position
Unknown
AA seq
2294 aa
AA seq
DB search
MTSEEMAASVLTPVTQRKVTSTPSAIDESSEKVSDISVLKAHSIRQSGQTSTTAQMNKLN
EEPSGSNLPKILSIAREKIVSDENSNEECWTESTPVSVENLNINQNNVLTKSQCYDMCDS
VMEEDPYLETGIPSSLEREVFPGIQLEIDGPPMDISPLGSQSAVIETGQAHPDGNTAAFH
FHYEVDRRVSDTFCTLSGNLILDDCGNCVPLPDVGGEQKKNYAAYTCKLMELAENCDNKN
GQLQCDHCDTLDDNYLCFEGSCRRASVLCSSDSLCREDLTNSPPAKTFLSHFEDFPDNCE
DVEEDFFKSKKERSTLLVRRFCKNDREIKKSVYTGTRAIMRTLPSGHIGLEAYSYIDQKR
SGLLLPCGRVLEQLSVVAIRQDGSQCLSEAQWYRIYNAVRSREEIENTIESLLHVFTNLP
ASEAAHERISIGPCLKQCVQDTICEYRATLQRTSISQYITGSLLEATTSLGARSGLLSTF
GGSTGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILMEQEQNIY
RRVLPVDYLCFLTRDLGTPECQTSLPCLKASISASILTSQNGEHNALEDLVMRFNEVSSW
VTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMWQFMDQSD
LETMRSLKDAMAQHESSCEYRKVVTRALHIPGCKVVPFCGVFLKELCEVLDGASGLMKLC
PRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQTIRSCSRSLEAEDED
SPSEGNSSRKNSLRDKARWQFIIGDLLDSENDIFEQSKEWDSHGSEEPQKAFDHGTELIP
WYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWIKPTTASPASAKAK
LGVLSNTSEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQNKLGSMFL
SETGVTLLYGLQTTDNRLLHFVAPKHTAKMLFSGLLELTRAVRKMRKFPDQRQQWLRKQY
VSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPSVQRNNTLGISTTKKK
KKILIRGESGEAADDEMATRKAKMQRESRSRSGSDPQDVNEQEESEANAVMSPPNTLPSR
RAHSLTTAGSPNLSAGVSSPIRPVSSPVLSSSNKSLSSAWSSSSWHGRIKGGMKGFQSFM
VSDSNMSFVEFVELFKSFSVRSRKDLKDLFDIYAVPCSRAGSESAPLYTNLTIDENTSDL
QPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLGIFGVGIL
QLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNFASKNDES
QEDIKDLQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDCWDGDDGM
PIIYHGHTLTTKIPFKEVVEAIDRSAFINSDLPIIISIENHCSLPQQRKMAEIFKTVFGE
KLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLASMQAQAY
NGGNANPPPANNEEEEDEEDEYDYDYESLSDDNILEDRPENKSCNDKLQFEYNEEIPKRI
KKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELSDLVIYCQAVKFPGLSTLNASG
SSRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSSCEGMRQAWEESSSPLNPTTSLSA
IIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLRTYPAATRIDSSNPNPLMFWLH
GIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLWDKNCPMYQKFSPLERDLDNME
PAVYSLTIVSGQNVCPNSSTGSPCIEVDVLGMPLDSCHFRTKPIHRNTLNPMWNEQFLFR
VHFEDLIFLRFAVVENNSSAVTAQRIIPLKALKRGYRHLQLRNLHNEVLEISSLFINSRR
MEENSSSSAVPASLMFNTEERKCLQTHKVTVHGVPGPEPFTVFSINGGTKAKQLLQQILT
TEQNTKPIVTDYFLMEEKFFISKEKNECRKQPFQRVIGPEEEIMQILSSWFPEEGYVGRI
VLKTQQENLEERSIIQDDKEVILSSEEESFFVQVHDVSPEQPRTVIKAPRVSTAQDVIQQ
TLCKAKYSYSILSNPNPSDYVLLEEVVKDATKKSSTPKSSQRVLLDQECVFQAQSKWKGA
GKFILKLKEQVQASREDRRKGISFASEFKKFTKSTKQPRGLTSSSLVLASESVQSKEEKP
VGSLPSSDAIDYRQ
NT seq
6885 nt
NT seq
+upstream
nt +downstream
nt
atgacatcagaagaaatggcagcttctgttctcacacctgtaactcagagaaaagtgaca
tccactccatcggctatagatgaaagtagtgaaaaggtctcagacatcagtgttctgaag
gcacatagcatcaggcagagtgggcagacttctaccactgcacagatgaacaagcttaac
gaagaaccttctggaagcaacttgcccaagattctctcaatagcaagggagaaaatagtg
agtgatgagaacagcaatgaagagtgctggacagaaagcacaccagtttctgtggaaaac
cttaatattaaccaaaacaacgtactgacaaagagccagtgttatgacatgtgtgattct
gtcatggaggaagacccatatttggaaactggaatcccatcctcactggaaagagaggtg
ttccctggaattcaactggaaattgatggacctcccatggacattagtcccttaggaagt
cagtcggccgtcatagagactggccaggcacaccctgatggcaacacagcagcatttcac
tttcactatgaagttgacagaagagtgtcagatactttctgtaccctgtcaggcaacttg
attttagatgattgtggaaactgtgtaccactgcctgatgttggtggggagcaaaagaaa
aattatgcggcatatacttgtaaacttatggaattggctgaaaactgtgataataagaat
gggcagctgcaatgtgatcattgtgacaccttggatgacaattacttatgctttgaaggt
tcttgccgaagggccagtgtgctatgttcaagtgacagcctttgcagggaggacttgact
aacagtccccctgccaagacttttctgagccattttgaggacttccctgataactgtgaa
gatgtagaagaagatttttttaagagcaaaaaggagaggtccactttgttagtgaggaga
ttttgtaaaaatgacagggaaataaagaaatctgtgtatactgggacaagggcaatcatg
aggactctgccttctggtcacattgggctggaagcttacagttacatcgatcagaagaga
agtggtcttttattgccctgtgggagagttctggaacagctgtcagtggtggcaattagg
caggatggaagccagtgcctatcagaagcccagtggtatcggatctacaatgcagtgaga
agcagagaagaaatagaaaatacaattgaatctcttctccatgtcttcacaaatctcccg
gcctccgaggcagcccatgaaaggattagcattggtccatgcttaaaacagtgtgtccaa
gacaccatatgtgagtaccgggccaccctccagagaacgtccatatctcagtacatcacg
ggctctctcctagaagcaaccacatctttgggagcaagaagtggcctactcagtactttt
ggaggatccactggacgaatgatgctaaaagaacgccagccaggcacctccatggccaat
tccagtgccctcccttcaagttcagctgggatcagcaaggaactgattgacctccagccc
ctcattcagttcccagaggaagtcgccagcatcctgatggagcaggaacagaacatttac
cgaagggtcttgccagttgactacctttgcttcttgacccgggacttaggcactccggaa
tgccagacatccctgccctgcctcaaagcatccatctcagcttcgattcttacctcccag
aatggagagcacaatgccctggaagatctggtgatgagatttaatgaggtgagctcttgg
gtgacgtggctgatcctcacggcgggctccatggaggagaagcgggaagtcttctcctat
ttggtgcatgtggccaaatgctgctggaacatgggcaactacaatgctgtcatggagttc
ttggctggcctcaggtcaagaaaagttttaaaaatgtggcagtttatggaccagtctgac
ctggagaccatgaggagcctgaaggacgccatggctcagcacgaatcttcctgcgagtac
aggaaggtggtcacgcgggccctgcacatacccggctgtaaggtggttccattctgtggg
gtgtttctgaaggagctctgtgaagtactggacggagcctctggcctcatgaagctttgc
ccgaggtacaattcccaagaagaaactctagagtttgtagccgattacagcggacaagat
aatttcttacaacgagtgggacataatggcttaaagaattcagagaaggagtccactgtc
aacagcatctttcagaccatcagaagctgtagccgaagtctggaggcagaggatgaagac
agccccagcgaaggcaacagctctaggaaaaattccttgagggataaagcacggtggcag
tttataattggagatctgttggattctgaaaatgacatctttgagcagtcgaaagaatgg
gactctcatggatcagaagagccacagaaggcctttgaccatggcacggagctgatccca
tggtacgtgctgtccatccgagctgatgtgcaccagttcctactgcagggggccactgtc
atccactatgaccaggacacacacctgtccgcccgctgcttccttcagcttcagcctgac
aacagcaccttgacctggataaagcccaccactgcctccccagccagtgctaaagcaaaa
cttggtgtgcttagtaacacgtctgagcctggcaaattccccttactgggcaatgctgga
ttaagtggcctggcggagggggtcttggatctgttttcagcaaaggctgtgtacatggga
caccctagcatcgatatacacactgtgtgtgttcagaacaaactgggtagcatgtttctc
tccgagactggtgtgacactgctctatgggctccagaccacagacaacagattattgcac
tttgtggcgcccaagcacacagctaagatgctcttcagcggattgctagaactcacgagg
gccgtgaggaagatgaggaagttcccggaccagagacagcagtggctgcggaaacagtac
gtcagcctctatcaggaggacggacggtatgaaggcccaactttggctcacgctgtggag
ctgttcggtggccggcgatggagtacacgcaaccccagccctgggacatctgcgaagagt
gctgagaagcccagtgtgcagaggaacaacacactgggcataagcaccaccaagaaaaag
aagaaaatccttatacggggtgagagtggagaggcagctgatgacgagatggccacgcgg
aaggccaaaatgcagagggagagtcgcagtcggagtggttcagaccctcaagacgtgaat
gagcaagaagaatccgaggcaaatgccgtcatgagccctcctaacactctgccttccaga
agagcccactccttgaccacggctgggtcccccaacttgtctgctggagtatcatctccc
atcaggccagtgtcttcccctgtgctgtcttcttcaaacaagagcctgtccagtgcttgg
agcagcagcagctggcacgggaggatcaaaggaggaatgaagggttttcagagcttcatg
gtttccgacagtaacatgagtttcgttgaatttgttgagctgttcaaatcattcagcgtg
aggagccgtaaggacctaaaggatctctttgacatctacgccgtgccctgcagccgagcc
ggctccgagtcagcccctctctacaccaacctaaccatcgacgaaaacaccagtgatctt
cagcctgacctagatttactgaccagaaatgtctcggacttggggttgttcattaagagt
aagcagcagctgtcagacaaccagaggcagatatctgatgccattgctgctgcgagtatc
gtgactaatggcactggggtcgagagcacgtctctgggcatctttggggtcggcatactc
cagctcaatgacttccttgtcaactgccagggagagcactgcacttacgatgaaatcctc
agtatcattcagaagttcgagcctagcgttagtatgtgtcatcagggcctactgtcattt
gagggatttgcaaggtttctgatggataaagataattttgcctccaaaaatgacgagtca
caggaagacattaaagacttgcagctgcccctgtcctactattacattgaatcttcacac
aatacctacctcacaggccaccagctcaaaggagagtcctcagtggaactctacagtcag
gtcctcctacaaggctgcaggagtgtagagttggactgctgggatggagatgatgggatg
cccatcatctaccacgggcacacgctgacaaccaagatccccttcaaggaggtggttgaa
gccattgaccgcagtgccttcatcaactctgacctgcccatcatcatatcaattgagaac
cactgctccttgcctcagcaacgaaaaatggcagaaattttcaagactgtgtttggagaa
aaactggtggcaaaattcctgtttgagagcgatttctcagatgatccaatgcttccctca
cctgaccaacttaggaggaaagtacttcttaaaaataagaagctaaaagctcaccagacg
ccagtggatatcttaaagcaaaaggctcatcagttagcatccatgcaagctcaggcttat
aatggggggaatgccaaccccccacctgctaataacgaggaagaggaggatgaagaggat
gaatatgattatgactatgaatctctgtctgatgacaacattctagaagacagacctgaa
aataaatcatgtaatgacaagcttcagtttgagtataatgaagaaatccccaagaggata
aagaaagcagataactctgcctgcaacaaaggaaaggtttatgacatggaattgggagaa
gaattttatcttcctcagaataaaaaggaaagcagacagattgcaccagagctttctgac
cttgtcatctattgccaagcagtaaaatttccaggcctgtcaactctaaatgcatctggc
tctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggcaga
atgagccctggggagacagcatcgtttaacaaagcatctggaaaaagttcctgtgaagga
atgcggcaggcctgggaggaatcttcttcccccctgaacccaaccacatccctcagcgct
atcattagaactcccaaatgttaccatatctcatcgctgaatgaaaatgccgccaaacgt
ctgtgtcgcaggtattctcagaaactgatccagcataccgcctgtcagctgctgaggacc
tacccggctgccacccgcatcgactcctccaaccccaatcccctcatgttctggctccat
gggattcagctcgtggcgctcaactaccagacagatgatctccccttacatttaaatgct
gccatgtttgaggccaacggtggctgtggctatgttctgaaacccccagttctgtgggac
aagaactgtcccatgtatcaaaagttttcacccttggaaagagacctggacaacatggag
cctgccgtctattccttaactatcgtctctggtcaaaacgtgtgtccaaacagcagcacg
gggagcccgtgcatcgaagtcgacgtcctgggcatgcccctggacagctgccacttccgc
acaaagcccatccaccggaacactctgaaccccatgtggaacgaacagtttctcttccgg
gttcactttgaagacctcatatttcttcgttttgcggttgtggaaaacaacagctcggct
gtgactgctcagagaatcatcccactcaaggctttaaaacgaggttatcggcatcttcag
ctgcgaaacctccacaatgaagtcttggaaatctctagtttattcataaacagcagaagg
atggaagaaaactcctccagcagtgctgtgccggcctctttgatgtttaatacagaagaa
agaaaatgtttgcagactcacaaagtcacagtgcatggggtcccgggtccagagcccttt
actgttttctccataaatggtggcaccaaggcaaagcaacttctccaacaaattctgacg
actgaacaaaacaccaaacctattgtcacagactattttttgatggaagaaaaatttttt
atatctaaggaaaagaatgaatgcaggaaacaaccattccaaagagtcattggtccagaa
gaagagatcatgcagattttaagcagctggtttccagaggaaggctatgttggcaggatt
gtcttaaaaacccagcaggaaaacctagaagagagaagcattattcaagatgacaaggag
gtgatcctgagctccgaggaggagagtttctttgtccaagtgcatgatgtttctccagag
caacctcgaacggtcatcaaagcgccccgtgtcagcaccgcacaggatgtcattcagcag
accttatgcaaagccaaatattcctatagcatcctgagcaaccccaacccgagtgactat
gtgcttttggaagaagtggtgaaagatgctaccaagaagtcttctaccccgaagtcctcc
cagagggttcttttggatcaggaatgtgtgtttcaagcccagagcaagtggaaaggtgca
ggaaaattcatccttaagctaaaggagcaggtgcaggcatccagagaagacagaagaaaa
ggcatttcttttgcaagtgaattcaagaagttcaccaagtcaactaaacagccccgagga
ctcacatcatcttctctggtcttggcctcagaaagtgtccaaagcaaggaggagaaacca
gtgggcagcttgccctccagtgatgccatagactaccgacaataa
DBGET
integrated database retrieval system
