Mycobacterium tuberculosis H37Ra: MRA_1197
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Entry
MRA_1197 CDS
T00540
Symbol
rocA
Name
(GenBank) delta-1-pyrroline-5-carboxylate dehydrogenase
KO
K00294
1-pyrroline-5-carboxylate dehydrogenase [EC:
1.2.1.88
]
Organism
mra
Mycobacterium tuberculosis H37Ra
Pathway
mra00250
Alanine, aspartate and glutamate metabolism
mra00330
Arginine and proline metabolism
mra01100
Metabolic pathways
Module
mra_M00970
Proline degradation, proline => glutamate
Brite
KEGG Orthology (KO) [BR:
mra00001
]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
MRA_1197 (rocA)
00330 Arginine and proline metabolism
MRA_1197 (rocA)
Enzymes [BR:
mra01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.88 L-glutamate gamma-semialdehyde dehydrogenase
MRA_1197 (rocA)
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Gene cluster
GFIT
Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-ProteinID:
ABQ72935
UniProt:
A5U1N5
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Position
1330701..1332332
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AA seq
543 aa
AA seq
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MDAITQVPVPANEPVHDYAPKSPERTRLRTELASLADHPIDLPHVIGGRHRMGDGERIDV
VQPHRHAARLGTLTNATHADAAAAVEAAMSAKSDWAALPFDERAAVFLRAADLLAGPWRE
KIAAATMLGQSKSVYQAEIDAVCELIDFWRFNVAFARQILEQQPISGPGEWNRIDYRPLD
GFVYAITPFNFTSIAGNLPTAPALMGNTVIWKPSITQTLAAYLTMQLLEAAGLPPGVINL
VTGDGFAVSDVALADPRLAGIHFTGSTATFGHLWQWVGTNIGRYHSYPRLVGETGGKDFV
VAHASARPDVLRTALIRGAFDYQGQKCSAVSRAFIAHSVWQRMGDELLAKAAELRYGDIT
DLSNYGGALIDQRAFVKNVDAIERAKGAAAVTVAVGGEYDDSEGYFVRPTVLLSDDPTDE
SFVIEYFGPLLSVHVYPDERYEQILDVIDTGSRYALTGAVIADDRQAVLTALDRLRFAAG
NFYVNDKPTGAVVGRQPFGGARGSGTNDKAGSPLNLLRWTSARSIKETFVAATDHIYPHM
AVD
NT seq
1632 nt
NT seq
+upstream
nt +downstream
nt
atggacgcgatcacccaggtgccggttccggccaacgagccggtgcacgactatgcgccg
aaatccccggaacggacccggctgcgcaccgaactggcctccctggccgatcaccccatc
gacctgccgcacgtcatcggcggccgacaccggatgggcgacggcgagcgaatcgacgtc
gtgcagccgcaccggcacgccgccaggctgggcaccctgaccaacgccacccacgccgac
gccgcggccgccgtcgaagccgccatgtctgccaaaagtgactgggcggcactgccgttc
gatgaacgtgccgcggtgttcctgcgcgccgccgatctgttggccgggccgtggcgggaa
aagatcgccgccgcaaccatgctcggccaatccaagtcggtgtaccaggccgagatcgac
gcggtctgcgagctgatcgacttctggcggttcaacgtcgctttcgcccgacagattttg
gagcagcagccgatcagtggcccgggggaatggaaccggatcgactaccgcccgctggac
ggtttcgtctacgcgatcacgccgttcaacttcacctcgatcgccggcaatctgccgacc
gccccggctctgatgggcaacaccgtgatctggaagccgtcgatcacccagacgctggcg
gcctatctgaccatgcaactgctcgaggccgccgggttgccgcccggggtgatcaacctg
gtcactggcgacggattcgcggtttccgatgtggcactggccgatccacggctggccggc
atccacttcaccgggtcgacggctaccttcggccacctatggcagtgggtgggtaccaat
atcggccgctaccatagctatccgcgactggtcggcgagaccgggggcaaggacttcgtg
gtggcgcacgcctcggcccgcccggatgtgctgcgcacggccctgattcgcggagcattc
gattaccagggccagaagtgctcggcggtgtcgcgagcgtttatcgcgcattcggtgtgg
cagcggatgggcgatgagttgctggccaaagccgccgagctgcgctacggtgacatcacc
gacctgtccaactacggtggtgcgctgatcgaccagcgcgccttcgtcaagaacgtcgac
gccatcgaacgggccaaaggcgcggccgcggtcaccgtcgccgtcggcggcgaatacgac
gacagcgaaggctatttcgtgcgccccacggtgttgctctccgacgacccgaccgacgag
tcgtttgtcatcgagtacttcggtccgctgctgtcggtgcatgtctaccccgacgagcgc
tacgagcagatcctcgacgtcatcgacaccggatcccgctacgcgctgaccggcgcggtc
atcgccgacgaccggcaggccgtgctgaccgcgctggatcggctgcggttcgcggcgggg
aacttctatgtcaacgacaagccgacgggggcggtggtggggcgtcagccgttcggcggt
gcacgcggatcgggcaccaacgacaaggccggttcgccgttgaacctgctgcggtggacg
tcggcgcgcagcatcaaggagacgttcgtcgcggccaccgaccacatctacccgcacatg
gcggtcgactga
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