Meiothermus ruber DSM 1279: Mrub_0476
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Entry
Mrub_0476 CDS
T01193
Name
(GenBank) 2-oxo-acid dehydrogenase E1 subunit, homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
mrb
Meiothermus ruber DSM 1279
Pathway
mrb00010
Glycolysis / Gluconeogenesis
mrb00020
Citrate cycle (TCA cycle)
mrb00620
Pyruvate metabolism
mrb00785
Lipoic acid metabolism
mrb01100
Metabolic pathways
mrb01110
Biosynthesis of secondary metabolites
mrb01120
Microbial metabolism in diverse environments
mrb01200
Carbon metabolism
mrb01210
2-Oxocarboxylic acid metabolism
Module
mrb_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
mrb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Mrub_0476
00020 Citrate cycle (TCA cycle)
Mrub_0476
00620 Pyruvate metabolism
Mrub_0476
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Mrub_0476
Enzymes [BR:
mrb01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Mrub_0476
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GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_N
Transketolase_C
HipN
Motif
Other DBs
NCBI-ProteinID:
ADD27253
UniProt:
D3PMS8
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Position
461643..464366
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AA seq
907 aa
AA seq
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MVEDRELIAARAELSAEEQVKLEDLENQEWRESLEYVLRTAGRDRVAQLMEMLENYAYRN
GVVIHDKVNTPYVNTISLEHQPPYPGDLELEQRIANILRWNTIAIVQQANKKSDGIGGHI
ATYASIAELMEMGFNHFFRGHDAPDRDLVFYQGHMSPGVYARSYLEGRLTEDDLGKFRRE
LLGGPGRGLSSYPHPWLMPDYWEFPTVSMGLGPIQAIYQARFMRYLEDRGLKPKTNAKVW
AFLGDGEQDEVETLGALRVAASEELDNLIFVINANLQRLDGPVRGNSKVIQELESVYRGN
GWNVIKVVWGSAWDELFAKDTEGVLLERMEQLVDGESQRYAAYGGKELREKFFNTPALKK
LIEGLSDEDLDRLTLSRGGHDNRKIYAAYKAAVEHRGSPTVIIARTVKGYCLGPTAQAKN
VAHQVKKLTLEDLREARDHLGIPIPDEDLEKTPFYHPGKDSPEVRYMLERRKALGGLIPE
RRVREYRLKTPDLAFFEEFLAGSGGREISTTMAFVRMLTKLVRHPEVGKYIVPIVPDEAR
TFGMEGVISSVGIYSPKGQLYTPVDAGTVTVYRESETGQLLQEGINEAGAMSSFIAAGTA
YAHHGIPTIPFYIYYSMFGLQRVGDLVWAAADQRTKGFLLGATAGRTTLNGEGLQHEDGH
SHVLALPVPNMPAYDPAFAYELAVILQDGMKRMYQDGEDIFYYITLMNENYVQPAMPEPR
EETRQGILKGLYLFKKSELKKPKARVQLLGSGTILNEVIKAAEMLERDYGIAADIWSATS
YKTLYYEALETARTNRLNPSSKPRLSYVAQCLNPTEGPIVAASDYMKALPDLLSGYLNRP
IHSLGTDGFGRSETREALRDFFEVDAKHVVITALSALRGEGKVSASTFTEAIKKLGIDPK
REHPHKR
NT seq
2724 nt
NT seq
+upstream
nt +downstream
nt
atggttgaagaccgcgaactgatcgccgcccgggcagagctatctgctgaggagcaggtc
aagctagaagacctcgagaaccaggagtggcgcgagagcctcgagtacgttctgcgcact
gccgggcgcgaccgggtggcgcagctcatggagatgctcgagaactacgcctaccgcaac
ggggtggtcatccacgacaaggtcaacacgccttacgtaaacaccatctcgctggagcac
cagcccccctacccgggcgacctcgagctcgagcagcgcatcgccaatatcctgcgctgg
aacaccatcgccattgtgcagcaggccaacaaaaaatccgacggtatcggcgggcacatc
gccacctacgccagcatcgccgagctgatggagatgggcttcaaccactttttccgtggg
cacgacgcccccgaccgcgacctggtcttctaccaggggcatatgtcgccgggggtgtat
gcccgcagctacctggagggccgcctgaccgaggacgatctgggcaagttccgccgcgaa
cttttgggcgggccgggccggggtctttccagctacccccacccctggctgatgcccgac
tactgggagttccccaccgttagcatgggtctggggcccatacaggccatctaccaggcc
cgcttcatgcgctacctggaagaccggggcctcaaacccaagaccaacgccaaggtctgg
gcctttttaggcgatggcgaacaggacgaggtcgaaaccctgggggctttgcgggtggcc
gcgagcgaggagctcgacaacctgatcttcgtgatcaacgccaacctgcagcgcctcgac
gggccggtgcgcggcaactccaaggtcatccaggagctcgagagcgtctaccggggcaac
ggctggaacgtgatcaaggtggtctggggtagcgcctgggacgagctgtttgccaaagac
accgaaggcgtgctgctcgagcgcatggagcagctcgtggacggcgagagccagcgctac
gcggcctacggcggtaaggagctgcgcgagaagttcttcaacacccccgccctcaaaaaa
ctgatcgagggcctgagcgacgaagacctcgaccgcctgaccctttcgcgcgggggccac
gacaaccgcaagatctacgccgcctataaagccgctgtggagcaccgcggctcgcccacc
gtcatcatcgcccgcaccgtcaagggctactgcctggggcccaccgctcaggccaagaac
gtggcccaccaggtcaagaaactcaccctggaagacctgcgggaggcgcgggatcacctg
ggcattcccatccccgacgaagacctggagaagacccccttctaccaccccggcaaggat
tcgccggaggtcaggtacatgctcgagcgccgtaaagccctgggcggcctgattcccgag
cggcgggtgcgcgaataccggctcaaaacccccgatctggccttcttcgaggagttcctg
gcaggctccggcgggcgcgaaatctccaccaccatggccttcgtgcgcatgctgactaag
ctggtgcgccaccccgaggtgggcaaatacatcgtgcccatcgtgcccgacgaggcccgt
acctttggcatggagggcgtgatcagctcggtgggcatctactcgcccaagggccagctc
tacaccccggtggacgccggcaccgtgaccgtctaccgtgagtccgagaccggccaactg
ctgcaggagggcatcaacgaggccggggccatgagcagcttcatcgccgctggaactgcc
tacgcccaccacggcattcccaccatccccttttacatctactactcgatgtttggcctc
cagcgggtgggcgacctggtctgggcggcggccgatcagcgcaccaaaggcttcttgctg
ggggctaccgcgggccgcaccaccctgaacggcgagggcctgcagcacgaggacggccac
agccacgtgctggccctgccggtgcccaacatgccggcctacgacccggctttcgcctac
gagctggcggtcatcctgcaggatgggatgaagcgcatgtaccaggacggtgaggacatc
ttctactacatcaccctgatgaacgagaactatgtccagccggccatgcccgagccgcgc
gaggaaacccgccagggcatcctgaagggcctgtatttgttcaagaagagcgagctgaaa
aagcccaaggccagggtgcagctcctgggcagcggcaccatcctgaacgaggtgatcaaa
gcagcggagatgctggagcgggattatggcatcgccgccgacatctggagcgccaccagc
tacaagaccctctactacgaggccctcgagaccgcccgcaccaaccgccttaaccccagc
agcaagcccaggctgtcctatgtggcccagtgcctgaatcccaccgaaggccccatcgtg
gcggcctcggactacatgaaggccctgcccgatctgctctcgggctacctgaaccggccc
atccacagccttggcaccgatggttttgggcgttccgaaacccgcgaggctttgcgcgac
ttcttcgaagtggacgccaaacatgtggtgataacagccctttcggcgttgcgcggcgag
ggtaaggtcagtgccagcacctttaccgaggccatcaagaagcttggcattgaccctaag
cgggagcacccccacaaacgctaa
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