Methylocella silvestris: Msil_0519
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Entry
Msil_0519 CDS
T00802
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
msl
Methylocella silvestris
Pathway
msl00010
Glycolysis / Gluconeogenesis
msl00020
Citrate cycle (TCA cycle)
msl00620
Pyruvate metabolism
msl00785
Lipoic acid metabolism
msl01100
Metabolic pathways
msl01110
Biosynthesis of secondary metabolites
msl01120
Microbial metabolism in diverse environments
msl01200
Carbon metabolism
msl01210
2-Oxocarboxylic acid metabolism
Module
msl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
msl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
Msil_0519
00020 Citrate cycle (TCA cycle)
Msil_0519
00620 Pyruvate metabolism
Msil_0519
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
Msil_0519
Enzymes [BR:
msl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
Msil_0519
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GFIT
Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
ACK49491
UniProt:
B8EJT7
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Position
576716..577750
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AA seq
344 aa
AA seq
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MADASSSVRTESRSRKGTEPPPAPPVFTKEQEFKAYREMLLIRRFEEKAGQLYGMGLIGG
FCHLYIGQEAVVVGVMMAAKPGDQTITSYRDHGHMIACGMDPKGVMAELTGRRGGLSKGK
GGSMHMFSKEKHFYGGHGIVGAQVPLGTGLAFANRYRSNGNVSYTYFGDGAANQGQVYES
FNMAELWKLPVIFIVENNRYAMGTSVKRSSAMSDFSKRGQSFNIPGEQVDGMDVRAVKAA
IERARDWCVGGNGPIILEMQTYRYRGHSMSDPAKYRSKEEVQKMREEHDPIEQVRARLLR
DHNVPEDELKAIDAEVRAIVAEAVDFASHDPEPDPAELWTDILK
NT seq
1035 nt
NT seq
+upstream
nt +downstream
nt
atggccgacgcatcaagctccgtccgcaccgaatcacggtcccggaaagggactgaaccg
ccgccggcgccgcctgtcttcaccaaagagcaggaattcaaggcctatcgcgaaatgctg
ctgatccggcgcttcgaggagaaggccgggcagctctacggcatgggcctcatcggcggt
ttctgccacctctatatcgggcaggaggccgtcgtcgtcggcgtcatgatggcggcgaag
cccggcgatcaaaccatcaccagctaccgcgatcatggccatatgatcgcctgcggcatg
gatcccaagggagtcatggccgaactgaccggacgacggggcggcttgtcgaaaggcaag
ggcggctcgatgcacatgttctccaaggagaagcatttctacggcggccacggcatcgtc
ggcgcgcaggtgccgctcggaacgggcctcgccttcgccaatcgctaccgctccaacggc
aatgtctcctacacctatttcggcgatggcgcggccaatcaagggcaggtctacgaaagc
ttcaatatggcggagctttggaaactgccggttattttcatcgttgaaaacaaccgctac
gccatggggacgtcagtcaagcgctcctccgcgatgagcgacttttccaagcgcggccag
agcttcaatattcccggcgaacaggttgacggcatggatgtccgcgcggtcaaggcggcg
atcgaacgcgcccgcgactggtgcgtcggcggcaacggcccgatcatccttgagatgcag
acctatcgctatcgcggccactcgatgtcggatcccgccaaataccgctccaaggaagaa
gtgcagaagatgcgcgaggagcatgatccgatcgagcaggtcagggcgcggctgctgcgg
gaccacaatgtgcctgaggacgagctcaaggcgatcgacgccgaggttcgcgccattgtc
gccgaagcagtcgacttcgcctcgcatgaccccgagcccgatccggccgagctttggacc
gatattctgaaataa
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