Mycobacterium tuberculosis KZN 1435: TBMG_03130
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Entry
TBMG_03130 CDS
T00940
Name
(GenBank) fatty-acid oxidation protein fadB
KO
K01782
3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase / 3-hydroxybutyryl-CoA epimerase [EC:
1.1.1.35
4.2.1.17
5.1.2.3
]
Organism
mtb
Mycobacterium tuberculosis KZN 1435
Pathway
mtb00071
Fatty acid degradation
mtb00280
Valine, leucine and isoleucine degradation
mtb00310
Lysine degradation
mtb00362
Benzoate degradation
mtb00380
Tryptophan metabolism
mtb00410
beta-Alanine metabolism
mtb00640
Propanoate metabolism
mtb00650
Butanoate metabolism
mtb00907
Pinene, camphor and geraniol degradation
mtb00930
Caprolactam degradation
mtb01100
Metabolic pathways
mtb01110
Biosynthesis of secondary metabolites
mtb01120
Microbial metabolism in diverse environments
mtb01200
Carbon metabolism
mtb01212
Fatty acid metabolism
Module
mtb_M00087
beta-Oxidation
Brite
KEGG Orthology (KO) [BR:
mtb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
TBMG_03130
00650 Butanoate metabolism
TBMG_03130
09103 Lipid metabolism
00071 Fatty acid degradation
TBMG_03130
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
TBMG_03130
00310 Lysine degradation
TBMG_03130
00380 Tryptophan metabolism
TBMG_03130
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
TBMG_03130
09109 Metabolism of terpenoids and polyketides
00907 Pinene, camphor and geraniol degradation
TBMG_03130
09111 Xenobiotics biodegradation and metabolism
00362 Benzoate degradation
TBMG_03130
00930 Caprolactam degradation
TBMG_03130
Enzymes [BR:
mtb01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.35 3-hydroxyacyl-CoA dehydrogenase
TBMG_03130
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.17 enoyl-CoA hydratase
TBMG_03130
5. Isomerases
5.1 Racemases and epimerases
5.1.2 Acting on hydroxy acids and derivatives
5.1.2.3 3-hydroxybutyryl-CoA epimerase
TBMG_03130
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
3HCDH_N
ECH_1
ECH_2
3HCDH
NAD_binding_2
F420_oxidored
DAO
NAD_binding_8
Motif
Other DBs
NCBI-ProteinID:
ACT26224
LinkDB
All DBs
Position
complement(3453585..3455747)
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AA seq
720 aa
AA seq
DB search
MPDNTIQWDKDADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASA
KKTFFAGGDVKTMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEI
ALACHHRIAADVKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAK
AKEIGLVDELVATVEELVPAAKAWIKEELKANPDGAGVQPWDKKGYKMPGGTPSSPGLAA
ILPSFPSNLRKQLKGAPMPAPRAILAAAVEGAQVDFDTASRIESRYFASLVTGQVAKNMM
QAFFFDLQAINAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEA
AAKGKGYSEKLEAKALERGRTTQERSDALLARITPTADAADFKGVDFVIEAVFENQELKH
KVFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEK
TSDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGS
QAGYPAPPLQLSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRSGRLK
GAGFYEYADGKRSGLWPGLRETFKSGSSQPPLQDMIDRMLFAEALETQKCLDEGVLTSTA
DANIGSIMGIGFPPWTGGSAQFIVGYSGPAGTGKAAFVARARELAAAYGDRFLPPESLLS
NT seq
2163 nt
NT seq
+upstream
nt +downstream
nt
atgccagacaacacaatccagtgggacaaggatgccgacggcatcgtcacgctgaccatg
gacgatccctccgggtcaaccaacgtgatgaacgaggcctacatcgagtcgatgggcaag
gccgtcgatcgccttgtcgccgaaaaggattcgatcaccggagtggtagtcgccagcgcg
aagaaaaccttcttcgccggcggcgacgtcaagacgatgatccaggccaggcccgaggac
gccggcgatgtattcaacaccgtcgagaccatcaagcggcagctgcgcaccttggagaca
ttgggtaagccggtcgtcgcggccatcaacggggcggcgttgggcggcggcctggagatc
gcgctggcgtgtcatcaccggatcgccgccgacgtcaagggcagccagctcggtctgccg
gaggtgacgctgggtctgctgccgggtggcggtggggtgacccgcacggtacggatgttc
ggcatccagaacgcgttcgtgagcgtgctggcgcaaggtacccggttcaagccggccaag
gccaaggagatcggtctggtcgacgagctggtggcaacggtcgaggagctggtgcccgcc
gccaaggcttggataaaggaggagctcaaggccaaccccgacggtgccggggtgcagccg
tgggacaagaagggctacaagatgcccggcggcaccccgtcgtcgccgggtctggcggcg
attttgccgtcgttcccgtcgaacctgcgcaagcagctcaagggtgccccgatgccggcg
ccgcgggccatcctggccgccgcggtcgagggggcacaggtcgatttcgacaccgccagc
cgcatcgagagccgctacttcgcgtcgttggtcaccggccaggtcgccaagaacatgatg
caggcgttcttcttcgacctgcaggccatcaatgccggcgggtctcggcccgaaggcatc
ggcaagaccccgatcaagaggatcggtgtgctgggtgcgggcatgatgggcgccggcatc
gcctacgtctctgccaaggccggctatgaggtggtactcaaagatgtcagccttgaggcc
gccgctaaaggcaagggctactccgaaaagctggaggccaaggcgctggagcggggccgc
accacacaggagcgcagcgacgccctgctggcgcgcatcaccccgaccgccgacgccgcc
gatttcaagggcgttgatttcgtgatcgaggcggtttttgaaaaccaggagctcaagcac
aaggtgttcggcgagatcgaagacatcgtcgagcccaacgcgatcctgggatccaacacc
tcgacgctgccgatcaccggtctggcgaccggcgtcaagcggcaggaagactttatcggg
atccacttcttctcgccggtcgacaagatgccgctggtggagatcatcaagggcgagaag
acttctgacgaggccctggcccgggtgttcgactacaccttggccatcggcaagaccccg
atcgtggtcaacgacagccgcggctttttcacctcgcgggtcatcggcacgttcgtcaac
gaggcgctggcgatgctcggtgagggtgtcgagccggcttctatcgagcaggcggggtcg
caggccgggtatccggcgccgccgctgcagctgtccgacgagctcaacttggagctgatg
cacaagatcgccgtcgccacccgtaagggtgttgaggacgccggcggcacgtaccagccg
catccggcggaggccgtggtggagaagatgatcgagctcggccggtccggccggctgaag
ggcgcgggcttctacgagtacgccgacggcaagcgatccgggttgtggcccggcttgcgc
gagacgttcaagtcgggctcgtcgcagccgccgctgcaggacatgatcgaccgcatgctg
ttcgccgaggcgctggaaacccagaagtgcctcgacgagggggtgctgacgtcgacggcc
gacgccaacatcggctcgatcatgggcatcggcttcccgccgtggacaggtggcagtgcc
cagttcatcgtcggctactccggcccggccggtaccggtaaggcggctttcgtggcccgg
gcccgcgagctggcggccgcctacggcgaccgcttcctgccgccggagtcgctgctaagc
tga
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