KEGG   Macaca thibetana thibetana (Pere David's macaque): 126939323
Entry
126939323         CDS       T08579                                 
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
  KO
K11262  acetyl-CoA carboxylase / biotin carboxylase 1 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
mthb  Macaca thibetana thibetana (Pere David's macaque)
Pathway
mthb00061  Fatty acid biosynthesis
mthb00620  Pyruvate metabolism
mthb00640  Propanoate metabolism
mthb01100  Metabolic pathways
mthb01212  Fatty acid metabolism
mthb04152  AMPK signaling pathway
mthb04910  Insulin signaling pathway
mthb04922  Glucagon signaling pathway
mthb04936  Alcoholic liver disease
Module
mthb_M00082  Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:mthb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    126939323
   00640 Propanoate metabolism
    126939323
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    126939323
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    126939323
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    126939323
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    126939323
   04922 Glucagon signaling pathway
    126939323
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    126939323
Enzymes [BR:mthb01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     126939323
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     126939323
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     126939323
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3 MetallophosN
Other DBs
NCBI-GeneID: 126939323
NCBI-ProteinID: XP_050620509
LinkDB
Position
16:31992784..32322504
AA seq 2416 aa
MWWSTLMSILRASSFWRWISTQTIRIIRALRAHFGGIMDEPSPLAKPLELNQHSRFIIGS
VSEDNSEDEISNLVKLDLLEEKEGSLSPASVGSDTLSDLGISSLQDGLALHIRSSMSGLH
LVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIANNGIAAVKCMRSIRRWSYE
MFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPVPGGPNNNNYANVELILDIAKRIPVQ
AVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMWALGDKIASSIVAQTAGIPTLPWSGS
GLRMDWQENDFSKRILNVPQELYEKGYVKDVDDGLQAAEEVGYPVMIKASEGGGGKGIRK
VNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHLEVQILADQYGNAISLFGRDCSVQRR
HQKIIEEAPATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEYLYSQDGSFYFLELNPRLQ
VEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPIDFEDSAHVPCPRG
HVIAARITSENPDEGFKPSSGTVQELNFRSNKNVWGYFSVAAAGGLHEFADSQFGHCFSW
GENREEAISNMVVALKELSIRGDFRTTVEYLIKLLETESFQMNRIDTGWLDRLIAEKVQA
ERPDTMLGVVCGALHVADVSLRNSVSNFLHSLERGQVLPAHTLLNTVDVELIYEGVKYVL
KVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTTYMKEEVDRYRITIGNKTC
VFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTLTAVESGCIHYVK
RPGAALDPGCVLARMQLDNPSKVQQAELHTGSLPRIQSTALRGEKLHRVFHYVLDNLVNV
MNGYCLPDPFFSSKVKDWVERLMKTLRDPSLPLLELQDIMTSVSGRIPPNVEKSIKKEMA
QYASNITSVLCQFPSQQIANILDSHAATLNRKSEREVFFMNTQSIVQLVQRYRSGIRGHM
KAVVMDLLRQYLRVETQFQNGHYDKCVFALREENKSDMNTVLNYIFSHAQVTKKNLLVTM
LIDQLCGRDPTLTDELLNILTELTQLSKTTNAKVALRARQVLIASHLPSYELRHNQVESI
FLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFFYHSNQVVRMAALEVYVRRAYIAYEL
NSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLNRMSFSSNLNHYGMTHVASVSDVLLD
NSFTPPCQRMGGMVSFRTFEDFVRIFDEVMSCFSDSPPQSPTFPEAGHTSLYDEDKVPRD
EPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIRRLTFLVAQKDFRKQVNYE
VDRRFHREFPKFFTFRARDKFEEDRIYRHLEPALAFQLELNRMRNFDLTAIPCANHKMHL
YLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN
TNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMRYGSRLWKLRVLQAELKINIRLTPTG
KAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLL
QSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSPPLPSDMLTYTELVLDDQG
QLVHMNRLPGGNEIGMVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSFGPQEDWLFLRAS
ELARAEGIPRIYVSANSGARIGLAEEIRHMFHVAWVDPEDPYKGYRYLYLTPQDYKRVSA
LNSVHCEHVEDEGESRYKITDIIGKEEGIGPENLRGSGMIAGESSLAYNEIITISLVTCR
AIGIGAYLVRLGQRTIQVENSHLILTGAGALNKVLGREVYTSNNQLGGIQIMHNNGVTHC
TVCDDFEGVFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEFVPTKAPYDPRWMLAGRPH
PTQKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARLGGIPVGVVAVETRTVELSIPADPAN
LDSEAKIIQQAGQVWFPDSAFKTYQAIKDFNREGLPLMVFANWRGFSGGMKDMYDQVLKF
GAYIVDGLRECSQPVLVYIPPQAELRGGSWVVIDSSINPRHMEMYADRESRGSVLEPEGT
VEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSTAERKELENKLKEREEFLIPIYHQVA
VQFADLHDTPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLEDLVKKKIHNANPELTDGQ
IQAMLRRWFVEVEGTVKLGPGQSRGRHGFHHPYDPAHITYSASRSCTDPLHNGLPFHVGR
ASCLSLPLEKRARAAFYNCSHCNEKAQETQHWSQSGILLPPKCFRLRMTSWDVRSQNPSS
PPVTPTPFSIYYPSQA
NT seq 7251 nt   +upstreamnt  +downstreamnt
atgtggtggtctactctgatgtcaatcttgagggctagttctttttggaggtggatatct
actcagacaataagaattataagagctctaagagctcattttggaggaataatggatgaa
ccatctcccttggccaaacctctggagctgaaccagcactctcgattcataattggttct
gtgtctgaagataactcagaggatgagatcagcaacctggtgaagctggacctactggag
gagaaggagggttctttgtcacctgcttctgttggctcagatacactctctgatttgggg
atctctagcctacaggatggcctggccttgcacataaggtccagcatgtctggcttgcac
ctagtaaagcagggccgagacagaaagaaaatagattctcaacgagatttcactgtggct
tctccagcagaatttgttactcgctttgggggaaataaagtgattgagaaggttcttatt
gctaacaatggcattgcagcagtgaaatgcatgcggtctatccgtaggtggtcttatgaa
atgtttcgaaatgaacgtgcaattcgattcgttgtcatggtcacacctgaagaccttaaa
gccaatgcagaatacattaagatggcagatcactacgtgccggtgcctggaggaccaaac
aacaacaactatgcaaatgtggaattaattcttgatattgctaaaaggatcccagtacaa
gcagtgtgggctggctggggtcatgcttctgagaatcccaaactaccggaacttctcttg
aaaaatggcattgccttcatgggtcctccaagccaggccatgtgggctttaggggataag
attgcatcttccatagtggctcaaactgcaggtatcccaactcttccctggagtggcagt
ggtcttcgtatggactggcaggaaaatgatttttcaaaacgtatcttaaatgttccccag
gagctatatgaaaaaggttatgtgaaagatgtggatgacgggctacaggcagctgaggaa
gttggatatccagtaatgatcaaggcctcagaaggaggaggagggaagggaattagaaaa
gtcaacaatgcagatgacttccctaacctcttcagacaggttcaagctgaagtccctgga
tctcccatatttgtgatgagactagccaaacaatctcgtcatctggaggtgcagatctta
gcggaccaatatggcaatgccatctctttgtttggtcgtgattgctctgtacaacgcagg
catcagaagattattgaagaggcaccagctactattgctactccagcagtatttgaacac
atggaacagtgtgcggtgaaacttgccaaaatggtgggttatgtgagtgctgggactgtg
gaatacctgtacagccaggacggcagcttctactttctggaattgaatcctcggctacag
gtagagcacccttgtacagagatggtggctgatgtcaatctccctgcagctcagctccag
attgccatgggtattcctctatatagaatcaaggatatccgtatgatgtacggagtatct
ccctggggtgattctcccattgattttgaagattctgcacatgttccttgcccaaggggc
catgttattgctgctcggatcactagtgaaaatccagatgagggttttaagcccagttca
ggaacagttcaggaactaaatttccgcagcaataagaatgtttggggatacttcagtgtt
gctgctgcggggggacttcatgaatttgctgattctcagtttggtcactgcttttcttgg
ggagaaaacagagaggaggcaatttcaaacatggtggtggctttgaaggagctgtctatt
cggggtgactttcgaactacagttgaatacctgatcaaattgttagagactgaaagcttt
cagatgaacagaattgatactggctggctggacagactgatagcagaaaaagtacaggct
gagcgacctgacaccatgttgggggttgtatgtggggccctccacgtggcagacgtgagc
ctgcggaatagcgtctctaacttccttcactccttagaaaggggtcaagtccttcctgct
catacactgttgaatacagtagatgttgaacttatctatgagggagtcaagtatgtactt
aaggtgactcgacagtcccccaactcctatgtggtgatcatgaatggctcatgtgtagaa
gtagatgtacatcggctgagtgacggtggactgctcttgtcctatgatggcagcagttat
actacgtacatgaaggaggaagtggatagatatcgcatcacaattggcaataaaacctgt
gtgtttgagaaggaaaatgacccatcagtgatgcgctcaccttctgctgggaagttaatc
cagtacattgtagaagatggaggtcatgtgtttgctggccagtgctatgctgagattgag
gtgatgaagatggtaatgaccttaacagctgtggagtctggctgtatccattacgtcaag
cgacctggagcagctcttgaccctggctgtgtactagccagaatgcaactggacaacccc
agcaaggttcagcaggctgagcttcacacaggtagtctgccacggatccagagcacggca
ctcagaggcgagaaactgcatcgagtgttccattatgtcctggataatctggtcaacgta
atgaatggatactgcctgccagatcctttctttagcagcaaggtaaaagactgggtagag
cgattgatgaaaaccctcagagatccctccctgcctctcctagaattgcaagatatcatg
actagcgtgtctggccgcattccccccaatgtggagaagtctatcaagaaggaaatggct
cagtatgctagcaacatcacatcagtcctctgtcagtttcccagtcagcagattgccaac
atcctagatagccatgcagctacattgaaccggaaatctgaacgggaggtcttctttatg
aatactcagagcattgttcagctggtacagaggtaccgaagtggcatccgaggccacatg
aaggctgtggtgatggatctgctccggcagtacctgcgagtagagacacaattccagaat
ggtcactatgacaaatgtgtattcgccctccgggaagagaataaaagtgacatgaacact
gtactgaactacatcttctctcacgctcaagtcaccaagaagaatcttctggtcacaatg
cttatcgatcagttgtgtggccgggaccctactctcactgatgagctgctgaatattctc
acagagctaactcaactcagtaagactaccaatgctaaagtagcacttcgagcacgccag
gttcttattgcctcccatttgccatcatacgagcttcgccataaccaagtagagtctatc
ttcctatcagctattgacatgtatggacatcaattttgcattgagaacctgcagaaactc
atcctatcagaaacatctatttttgatgtcctaccaaacttcttctatcacagcaaccaa
gtagtgaggatggcagctctggaggtgtatgttcgaagggcttatattgcctacgaactt
aacagcgtacaacaccgccagcttaaggacaacacctgtgtggtggaattccagttcatg
ctgcccacatctcatccaaacagagggaacatccctacgctaaacagaatgtccttctcc
tccaacctcaaccactatggcatgacccatgtagctagtgtcagcgatgtgctgttggac
aactcattcactccaccttgtcagcggatgggcggaatggtctcttttcggactttcgaa
gattttgtcaggatctttgatgaagtgatgagctgcttctctgactccccaccccagagt
cccacattccctgaggcaggtcacacgtctctttatgatgaagataaggttcccagggat
gaaccaattcacattcttaatgtggctatcaagactgactgtgatattgaggatgacagg
ctggcagctatgttcagagaatttacccagcaaaataaagctaccctggttgaccatggg
atccggcgccttactttcctggttgcacaaaaggatttcagaaaacaggtcaactatgag
gtggatcggagatttcatagagaattccctaaattttttacattccgagcaagggataag
tttgaggaggatcgtatctatcgtcatctggagcctgctctggctttccagttagagctg
aaccggatgagaaattttgacctcactgccattccatgtgctaatcacaagatgcacctg
tatctcggggcagccaaggtggaagtgggcacagaagtgacagactacaggttctttgtt
cgtgcaatcatcaggcattctgatctggtcaccaaggaagcttcttttgaatatctgcaa
aatgaaggggagcggctactcctggaagccatggatgagttggaagttgcttttaacaat
acaaatgtccgcactgactgtaaccacatcttcctcaactttgtgcccacggttatcatg
gacccatcaaagattgaggaatctgtgcggagcatggtaatgcggtatggaagtcgcctg
tggaaattgcgcgtcctccaggcagaactgaaaatcaacattcgcctgacgccaactgga
aaagcaattcccatccgcctcttcctgacaaacgagtctggctattacttggatatcagc
ctatacaaggaagtgactgactccaggacagcacagatcatgtttcaggcatatggagac
aaacagggaccactgcatggaatgttaatcaatactccttatgtgaccaaagacctgctg
caatcaaagaggttccaggcacaatccttagggacaacatacatatatgatatcccagag
atgtttcggcagtccctgatcaaactctgggagtctatgtccactcaagcatttcttcca
tctccgcctctgccttctgacatgctgacttacaccgaactggtattggatgatcaaggt
cagctggtccacatgaacaggcttccaggaggaaatgagattggcatggtagcttggaaa
atgacctttaaaagtcctgaatatccagaaggccgagatatcattgttattggcaatgac
atcacataccgaattgggtcctttgggcctcaagaggattggttatttctcagagcttct
gaacttgccagggcagaaggtattccacgcatctatgtatcagccaacagtggagcaaga
atcggactggcagaagaaattcgtcatatgtttcatgtggcctgggtagatcctgaggat
ccttacaagggatacaggtatttatatctgacccctcaagattataagagagtcagtgct
ctcaactcggtccattgtgaacacgtggaggatgaaggagaatccaggtacaagataaca
gatattattgggaaagaagagggaattggacctgagaaccttcgaggttctggaatgatt
gctggagaatcctcattggcctataatgagatcattaccatcagcctggtgacgtgccgg
gccattgggattggggcttaccttgtccggctgggacagagaaccatccaggttgagaat
tctcacttaattctaacaggagctggagccctcaacaaagtcctcgggcgggaagtgtac
acctccaataaccagctcgggggcatccagatcatgcacaacaatggggtgacccactgc
actgtgtgtgatgactttgaaggggttttcactgtcctgcactggctgtcttacatgccc
aagagcgtgcacagttcagttcctcttctgaactcaaaggatcctatagacagaatcatc
gagtttgttcccacaaaggccccatatgatcctcgatggatgctagcaggccgtcctcat
ccaacccaaaaaggtcaatggttgagtggcttttttgactatggatctttctcagagatt
atgcagccctgggcacagactgtggtggttggtagagccaggctaggaggaatacctgtg
ggagttgttgctgtagaaacccgaacagtagagctaagtatcccagctgatccagcaaac
ttggattctgaagccaagataatccagcaggctggccaggtttggttcccagattctgcg
tttaagacgtatcaggccatcaaggacttcaaccgggaagggctgcctctgatggtcttt
gccaactggagaggcttctctggtggaatgaaagatatgtacgaccaagtgctgaagttt
ggtgcttacattgtggacggcttgagggagtgctcccagcctgtgctggtttacattcct
ccccaggctgagctgcggggcggctcctgggtagtgattgactcctccatcaatccccgg
cacatggagatgtatgctgaccgagaaagcaggggatctgttctggagccagaagggaca
gtagaaatcaaattccgcagaaaggatctggtgaaaaccatgcgtcgggtggacccagtc
tacatccacttggctgagcgattggggaccccggagctaagcacagctgaacggaaggag
ttggagaacaagttgaaggagcgggaagaattcttaattcccatttaccatcaggtagcc
gtgcagtttgctgacttgcacgacacaccaggccggatgcaggagaagggtgttattagc
gatatcctggattggaagacatcccgtaccttcttctactggcggctgaggcgtctcctg
ctggaggacctggtcaagaagaaaatccacaatgccaaccctgagctgactgacggccag
attcaagccatgttaaggcgctggtttgtggaagtggaaggtacagtgaagcttggtcca
ggccaatccagaggtcgccatggattccatcatccatatgacccagcacatatcacctac
tcagcgagcagaagttgtacggatcctctccacaatggactccccttccacgtaggaaga
gcttcctgcctgtccctgcctctggagaaaagggctagagctgccttttacaactgcagc
cactgtaatgagaaggcacaggagacccagcactggagtcaaagtggcattttacttcct
cccaagtgtttcaggttacgcatgacatcctgggatgtaagatcacagaacccctccagc
ccaccagtcacacccaccccattcagtatttattaccccagccaggcctag

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