Mycobacterium tuberculosis RGTB423: MRGA423_08715
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Entry
MRGA423_08715 CDS
T01994
Name
(GenBank) bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase
KO
K13038
phosphopantothenoylcysteine decarboxylase / phosphopantothenate---cysteine ligase [EC:
4.1.1.36
6.3.2.5
]
Organism
mti
Mycobacterium tuberculosis RGTB423
Pathway
mti00770
Pantothenate and CoA biosynthesis
mti01100
Metabolic pathways
mti01240
Biosynthesis of cofactors
Module
mti_M00120
Coenzyme A biosynthesis, pantothenate => CoA
Brite
KEGG Orthology (KO) [BR:
mti00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
MRGA423_08715
Enzymes [BR:
mti01000
]
4. Lyases
4.1 Carbon-carbon lyases
4.1.1 Carboxy-lyases
4.1.1.36 phosphopantothenoylcysteine decarboxylase
MRGA423_08715
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.5 phosphopantothenate---cysteine ligase (CTP)
MRGA423_08715
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Gene cluster
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Motif
Pfam:
DFP
Flavoprotein
YjeF_N
Motif
Other DBs
NCBI-ProteinID:
AFE12662
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Position
1566536..1567792
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AA seq
418 aa
AA seq
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MVDHKRIPKQVIVGVSGGIAAYKACTVVRQLTEASHRVRVIPTESALRFVGAATFEALSG
EPVCTDVFADVPAVPHVHLGQQADLVVVAPATADLLARAAAGRADDLLTATLLTARCPVL
FAPAMHTEMWLHPATVDNVATLRRRGAVVLEPATGRLTGADSGAGRLPEAEEITTLAQLL
LERHDALPYDLAGRKLLVTAGGTREPIDPVRFIGNRSSGKQGYAVARVAAQRGADVTLIA
GHTAGLVDPAGVEVVHVSSAQQLADAVSKHAPTADVLVMAAAVADFRPAQVATAKIKKGV
EGPPTIELLRNDDVLAGVVRARAHGQLPNMRAIVGFAAETGDANGDVLFHARAKLRRKGC
DLLVVNAVGEGRAFEVDSNDGWLLASDGTESALQHGSKTLMASRIVDAIVTFLAGCSS
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
gtggtggaccataaacggatccccaagcaggtaatagtcggtgtctccgggggcatcgcc
gcctacaaggcgtgcacggttgttcgtcaactcaccgaggccagtcatcgcgtccgagtc
attcccaccgaatccgccctgcgcttcgtcggtgccgcgaccttcgaggcgctctccggt
gagccggtgtgcaccgacgttttcgccgacgttccggcggtcccgcatgttcacctcggc
cagcaggccgatctggtcgtagtggcgccggccaccgccgacctgctggcccgcgcggcg
gccggtcgagccgacgatctgctgaccgcgacgctgctgacggcgcggtgtccggtgctg
ttcgcgccggcgatgcacaccgagatgtggttgcatccggccaccgtcgacaacgtggcc
acgctgcgccgccgcggcgcggtggtgctcgagcccgcgacaggacggcttaccggcgcc
gacagcggggccggccgactgcccgaggcggaggagatcaccaccctcgcccagctgctg
ctggagcggcacgacgccctgccctacgatctcgcggggcgaaagctgctggttaccgcc
ggtggcacacgcgagccgatcgatccggtgcgctttatcggcaaccgcagctccggcaag
cagggctatgcggtggcgcgggtggccgcccagcgcggcgccgacgttactttgatcgct
gggcataccgcagggctcgtcgatcccgccggcgtcgaggtggtgcacgtcagctcggcc
cagcaactcgccgacgcggtgtccaagcacgctccgaccgccgacgtattggtgatggcg
gcggccgtcgccgacttccggcccgcgcaggttgccaccgccaaaatcaagaaaggcgtc
gaaggcccaccgaccatcgagctgctgcgcaacgacgacgtgctggccggggtggtgcgg
gcccgagcccatggacaactgcccaacatgcgggccattgtgggcttcgcagccgagacc
ggcgacgccaatggcgacgtgctctttcatgcccgagctaaactgcgacgcaaaggctgc
gatctgttagtcgtcaatgccgtcggcgaaggcagggcctttgaggtagacagcaacgac
ggctggctactggcgtccgatggtaccgagtcggcattgcagcacggctccaagacactg
atggcgagccgtatcgttgatgcaatcgtcacgttcctggcaggctgtagcagctaa
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